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Melanoma Cell Adhesion Molecule (MCAM) ELISA Kits

Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Additionally we are shipping MCAM Antibodies (304) and MCAM Proteins (28) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
MCAM 4162 P43121
MCAM 84004 Q8R2Y2
MCAM 78967 Q9EPF2
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Top MCAM ELISA Kits at antibodies-online.com

Showing 9 out of 22 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 1.44 ng/mL 1.56-100 ng/mL 96 Tests Log in to see 9 to 11 Days
$700.00
Details
Mouse 0.251 ng/mL 0.62-40 ng/mL 96 Tests Log in to see 9 to 11 Days
$720.00
Details
Rat 0.39 ng/ml 1.56-100 ng/mL   96 Tests Log in to see 11 to 13 Days
$910.56
Details
Mouse 0.212 ng/mL 0.05-40 ng/mL   96 Tests Log in to see 9 to 11 Days
$909.47
Details
Chicken
  96 Tests Log in to see 8 to 9 Days
$770.00
Details
Monkey
  96 Tests Log in to see 8 to 9 Days
$770.00
Details
Guinea Pig
  96 Tests Log in to see 8 to 9 Days
$770.00
Details
Pig
  96 Tests Log in to see 8 to 9 Days
$770.00
Details
Rabbit
  96 Tests Log in to see 8 to 9 Days
$770.00
Details

Top referenced MCAM ELISA Kits

  1. Human MCAM ELISA Kit for Sandwich ELISA - ABIN414788 : Taylan, Sari, Kozaci, Yildiz, Bilge, Coker, Maltas, Gunay, Akkoc: Evaluation of various endothelial biomarkers in ankylosing spondylitis. in Clinical rheumatology 2012 (PubMed)
    Show all 3 references for ABIN414788

  2. Mouse (Murine) MCAM ELISA Kit for Sandwich ELISA - ABIN425012 : Thomann, Longerich, Bazhin, Mier, Schemmer, Ryschich: Selective targeting of liver cancer with the endothelial marker CD146. in Oncotarget 2014 (PubMed)

More ELISA Kits for MCAM Interaction Partners

Zebrafish Melanoma Cell Adhesion Molecule (MCAM) interaction partners

  1. CD146 regulates convergent extension movement during gastrulation

  2. In addition to the physiological angiogenesis during development, gicerin morphants efficiently blocked the tumor angiogenesis in zebrafish.

  3. CD146 protein expression has a role in vascular development in zebrafish

Human Melanoma Cell Adhesion Molecule (MCAM) interaction partners

  1. CD146 dexpression efines a subpopulation of human mesenchymal stem cells capable of bone formation and in vivo trans-endothelial migration.

  2. Results showed that CD146 promoted metastasis of hepatocellular carcinoma (HCC (show FAM126A ELISA Kits)) cells and predicted poor prognosis of HCC (show FAM126A ELISA Kits) patients. CD146 induced epithelial mesenchymal transition through probably IL-8 (show IL8 ELISA Kits) up-regulation and STAT1 (show STAT1 ELISA Kits) down-regulation.

  3. Data indicate that CD146 antigen is an effective cell surface marker for enriching tumor-propagating cells (TPCs) in primary sarcomas.

  4. MUC18 is an independent prognostic factor for clear cell renal cell carcinoma

  5. CD146 is a novel and useful marker for predicting senescence in human umbilical cord blood-derived Mesenchymal stem cells (hUCB-MSCs), and CD146 can potentially be applied in quality-control assessments of hUCB-MSC (show MSC ELISA Kits)-based therapy.

  6. ZBTB7A (show ZBTB7A ELISA Kits) directly binds to the promoter and transcriptionally represses the expression of MCAM, establishing ZBTB7A (show ZBTB7A ELISA Kits) as a bona fide transcriptional repressor of MCAM

  7. The expression of CD146 and HIF1a (show HIF1A ELISA Kits) was positively correlated with EGFR (show EGFR ELISA Kits) and CD31 (show HBA1 ELISA Kits), respectively in salivary gland adenoid cystic carcinoma.

  8. a model that CD166 (show ALCAM ELISA Kits) regulates MCAM through a signaling flow from activation of PI3K (show PIK3CA ELISA Kits)/AKT (show AKT1 ELISA Kits) and c-Raf (show RAF1 ELISA Kits)/MEK (show MAP2K1 ELISA Kits)/ERK (show EPHB2 ELISA Kits) signaling to the inhibition of potential MCAM ubiquitin E3 ligases, betaTrCP (show BTRC ELISA Kits) and Smurf1 (show SMURF1 ELISA Kits)

  9. Combined EpCAM (show EPCAM ELISA Kits)/MCAM CellSearch enrichment thus increased the CTC detection rate.

  10. Results identified MCAM as a novel YAP (show YAP1 ELISA Kits) target in hepatocellular carcinoma (HCC (show FAM126A ELISA Kits)) but not in breast and colon cancer cells. MCAM serum levels were specifically elevated in HCC (show FAM126A ELISA Kits) suggesting it as a specific diagnostic tool for HCC (show FAM126A ELISA Kits).

Mouse (Murine) Melanoma Cell Adhesion Molecule (MCAM) interaction partners

  1. Data show that CD146 was significantly higher expressed on tumor endothelium than on the liver.

  2. Conditional knockout of the cd146 gene in the murine endothelium or disruption of netrin-CD146 interaction by a specific anti-CD146 antibody blocks or reduces netrin-1 (show NTN1 ELISA Kits)-induced angiogenesis.

  3. MCAM is expressed by encephalitogenic CD8 (show CD8A ELISA Kits)+ T lymphocytes in experimental autoimmune encephalomyelitis. Blocking or depleting MCAM in vivo reduces chronic neurological deficits in active, transfer, and spontaneous progressive EAE models.

  4. Study demonstrate for the fi rst (show SLC22A12 ELISA Kits) time that host CD146 contributes to hematogenous melanoma cell metastasis through a novel mechanism involving the VEGF (show VEGFA ELISA Kits)/FAK (show PTK2 ELISA Kits)/Ve-cadherin (show CDH5 ELISA Kits) network.

  5. Suggest endothelial CD146 as a target for specific drug delivery in hepatocellular carcinoma.

  6. CD146 plays a dual role on endothelium, facilitating leukocyte extravasations and angiogenesis, thus promoting inflammation.

  7. CD146 deletion in the nervous system impairs appetite, locomotor activity and spatial learning in mice.

  8. Identified a novel negative regulator of angiogenesis, microRNA 329 (miR (show MLXIP ELISA Kits)-329), that directly targeted CD146 and inhibited CD146-mediated angiogenesis in vitro and in vivo.

  9. Alterations in CD146 are involved in the basic etiology of COPD (show ARCN1 ELISA Kits)/pulmonary emphysema.

  10. MUC18 exerts a proinflammatory function during lung bacterial infection.

Pig (Porcine) Melanoma Cell Adhesion Molecule (MCAM) interaction partners

  1. expression of FLK1 (show KDR ELISA Kits), CD146 and microvessel density of angiogenesis at the first week of reperfused acute myocardial infarction.

MCAM Antigen Profile

Antigen Summary

Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.

Gene names and symbols associated with MCAM

  • melanoma cell adhesion molecule (MCAM) antibody
  • melanoma cell adhesion molecule b (mcamb) antibody
  • similar to melanoma cell adhesion molecule (LOC566921) antibody
  • melanoma cell adhesion molecule (Mcam) antibody
  • 1-gicerin antibody
  • AV025631 antibody
  • CD146 antibody
  • CD149 antibody
  • gicerin antibody
  • id:ibd3512 antibody
  • MCAM antibody
  • Muc18 antibody
  • s-endo antibody
  • s-gicerin antibody

Protein level used designations for MCAM

cell surface glycoprotein MUC18 , melanoma adhesion molecule , cell adhesion molecule , similar to melanoma cell adhesion molecule , melanoma cell adhesion molecule , cell surface glycoprotein MUC18-like , Gicerin , S-endo 1 endothelial-associated antigen , cell surface glycoprotein P1H12 , melanoma-associated antigen A32 , melanoma-associated antigen MUC18 , HEMCAM , gicerin , l-gicerin protein , l-gicerin

GENE ID SPECIES
281301 Bos taurus
338313 Danio rerio
566921 Danio rerio
744688 Pan troglodytes
100071414 Equus caballus
100454353 Pongo abelii
100470323 Ailuropoda melanoleuca
4162 Homo sapiens
448832 Gallus gallus
84004 Mus musculus
489368 Canis lupus familiaris
78967 Rattus norvegicus
733617 Sus scrofa
100718224 Cavia porcellus
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