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May function in membrane fusion and regulate organelle biogenesis (By similarity). Additionally we are shipping MREG Proteins (7) and and many more products for this protein.
Showing 10 out of 48 products:
Human Polyclonal MREG Primary Antibody for WB - ABIN527623
Frost, Lopes, Bragin, Reyes-Reveles, Brancato, Cohen, Mitchell, Williams, Boesze-Battaglia: The Contribution of Melanoregulin to Microtubule-Associated Protein 1 Light Chain 3 (LC3) Associated Phagocytosis in Retinal Pigment Epithelium. in Molecular neurobiology 2014
Taken together, MREG regulates thyroid cancer cell invasion and proliferation through PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies)-mTOR (show FRAP1 Antibodies) signaling pathway. MREG may serve as a promising therapeutic strategy for thyroid cancer.
MREG-dependent processing links both autophagic and phagocytic p (show MAP1LC3A Antibodies)rocesses in (show ATG5 Antibodies) LC3-associated phagocytosis. MREG participates in coordinating the (show RPE Antibodies) assoc (show ATG5 Antibodies)iation of p (show MAP1LC3A Antibodies)hagosomes with LC3 for content degradation with the MREG loss leading to phagosome accumulation.
Single membrane POS containing phagosomes recruit endogenous LC3 (show MAP1LC3A Antibodies) in an ATG5 (show ATG5 Antibodies)-dependent manner that is dependent on MREG. In the Mregdsu/dsu RPE (show RPE Antibodies), Atg5 (show ATG5 Antibodies)/12 and LC3 (show MAP1LC3A Antibodies) were increased relative to levels in the Mreg+/+ at all time points relative to light onset.
This study demonistrated that Loss of melanoregulin (MREG) enhances cathepsin-D (show CTSD Antibodies) secretion by the retinal pigment epithelium.
The product of the Mreg(dsu) locus, melanoregulin (MREG), interacts both with members of BLOC-2 (show HPS6 Antibodies) complex and with ocular albinism in regulating melanosome size.
Mreg regulates microtubule-dependent retrograde melanosome transport through the dynein-dynactin (show DCTN1 Antibodies) motor complex.
multiple palmitoylation serves to stably anchor melanoregulin in the melanosome membrane.
Melanoregulin regulates a shedding mechanism that drives melanosome transfer from melanocytes to keratinocytes.
dsu identifies a unique protein involved in pigmentation of the mammalian hair
melanoregulin regulates peripherin-2 (show PRPH2 Antibodies) function
Results suggest that melanoregulin (MREG) is required for lysosome maturation and support a role for MREG in intracellular trafficking.
May function in membrane fusion and regulate organelle biogenesis (By similarity).
, whn-dependent transcript 2-like
, dilute suppressor protein homolog
, whn-dependent transcript 2
, dilute suppressor protein