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Membrane Protein, Palmitoylated 3 (MAGUK P55 Subfamily Member 3) Proteins (MPP3)

MPP3 product is a member of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs). Additionally we are shipping Membrane Protein, Palmitoylated 3 (MAGUK P55 Subfamily Member 3) Antibodies (75) and Membrane Protein, Palmitoylated 3 (MAGUK P55 Subfamily Member 3) Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MPP3 53310 P70175
MPP3 58948 Q62936
MPP3 4356 Q13368
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Top Membrane Protein, Palmitoylated 3 (MAGUK P55 Subfamily Member 3) Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,681.33
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 19 Days
$785.40
Details

MPP3 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Rat (Rattus)

Human , ,
,

More Proteins for Membrane Protein, Palmitoylated 3 (MAGUK P55 Subfamily Member 3) (MPP3) Interaction Partners

Mouse (Murine) Membrane Protein, Palmitoylated 3 (MAGUK P55 Subfamily Member 3) (MPP3) interaction partners

  1. The data of this studysuggested that MPP3 is required for maintaining proper levels of PALS1 (show MPP5 Proteins) at the subapical region, and indicate that the MPP3 gene is a candidate modulator of the Crumbs complex.

  2. our current study identified a functional interplay between PSD-95 (show DLG4 Proteins) and synapse-associated protein 102 (SAP102 (show DLG3 Proteins)) to regulate synaptic AMPA (show GRIA3 Proteins) receptors

  3. This study show that MPP3 is required for maintenance of the apical protein complex and adherens junctions and for stratification and proper migration of neurons during the development of the cortex.

  4. SAP102 (show DLG3 Proteins) has a fundamental role in trafficking the NMDA receptor complex to the synaptic sites.

  5. The Dlg3 (show DLG3 Proteins) have functions in complex cognitive processes.

  6. Synapse associated protein 102 (SAP102 (show DLG3 Proteins)) binds the C-terminal part of the scaffolding protein neurobeachin.

  7. Dlg3 (show DLG3 Proteins) exerts a distinct function by recruiting the ubiquitin ligases Nedd4 and Nedd4-2 (show NEDD4L Proteins) through its PPxY motifs. These interactions are required for Dlg3 (show DLG3 Proteins) monoubiquitination, apical membrane recruitment, and tight junction consolidation.

  8. Membrane-associated guanylate kinase (show GUK1 Proteins) homolog SAP102 (show DLG3 Proteins) is a central organizers of the postsynaptic density at excitatory synapses on pyramidal neurons.

  9. This indicates that, overall, interaction of 5-HT(2C) receptors with PDZ proteins inhibits receptor desensitization in cortical neurons.

  10. SAP102 (show DLG3 Proteins) interacts with the PDZ-binding domain of Sec8 (show EXOC4 Proteins), a member of the exocyst complex. nteractions between the two proteins are involved in the delivery of N-methyl-D-aspartate receptors to the cell surface in heterologous cells and neurons.

Human Membrane Protein, Palmitoylated 3 (MAGUK P55 Subfamily Member 3) (MPP3) interaction partners

  1. a central role of CADM1 (show CADM1 Proteins) in stabilizing the complex with 4.1B (show EPB41L3 Proteins) and MPP3

  2. MPP3 and Dlg (show DLG4 Proteins), membrane-associated guanylate kinase (show GUK1 Proteins) homologs (MAGuK) proteins, connect CADM1 (show CADM1 Proteins) with p85 of PI3K (show PIK3CA Proteins) by forming a multi-protein complex at the periphery of cells.

  3. MPP3 plays an important role in hepatocellular carcinoma metastasis by promoting cell migration and invasion via up-regulating MMP1 (show MMP1 Proteins)

  4. Data suggested that epigenetic inactivation of MPP3 frequently occurred during the development of colorectal cancer and might also be a potential biomarker for molecular classification of colorectal cancer patients.

  5. TSLC1 (show CADM1 Proteins) strongly inhibits the growth of HepG2 cells in vitro and induces apoptosis.

  6. MPP3, a human homologue of a Drosophila tumor suppressor gene (Discs large (show DLG4 Proteins)), associates with TSCL1, a tumor suppressor gene.

  7. These data implicate a role for MPP3 in photoreceptor polarity and, by association with MPP5 (show MPP5 Proteins), pinpoint MPP3 as a functional candidate gene for inherited retinopathies.

Membrane Protein, Palmitoylated 3 (MAGUK P55 Subfamily Member 3) (MPP3) Protein Profile

Protein Summary

This gene product is a member of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs). MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. This protein contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction. Alternatively spliced transcript variants have been identified. One transcript variant is experimentally supported, but it doesn't encode a protein.

Gene names and symbols associated with MPP3

  • discs, large homolog 3 (Drosophila) (Dlg3)
  • membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) (MPP3)
  • membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) (Mpp3)
  • 6430514B01 protein
  • CSG18 protein
  • Dlg3 protein
  • Dlgh3 protein
  • Dusp3 protein
  • mKIAA1232 protein
  • SAP102 protein

Protein level used designations for MPP3

SAP-102 , discs large homolog 3 , disks large homolog 3 , synapse-associated protein 102 , PSD-95/SAP90-related protein 1 , SAP102 , MAGUK p55 subfamily member 3 , discs, large homolog 3 , membrane protein palmitoylated 3 , Mpp3 membrane protein, palmitoylated 3 , protein Dlgh3

GENE ID SPECIES
53310 Mus musculus
58948 Rattus norvegicus
4356 Homo sapiens
419985 Gallus gallus
490947 Canis lupus familiaris
508710 Bos taurus
13384 Mus musculus
114202 Rattus norvegicus
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