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Mesoderm Specific Transcript (MEST) ELISA Kits

MEST encodes a member of the alpha/beta hydrolase superfamily. Additionally we are shipping MEST Antibodies (24) and MEST Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
MEST 17294 Q07646
MEST 58827 Q6P5P5
MEST 4232 Q5EB52
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Top MEST ELISA Kits at

Showing 4 out of 5 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Mouse 7.81 pg/ml 31.25-2000 pg/mL 96 Tests Log in to see 11 to 13 Days
96 Tests Log in to see 11 to 13 Days
96 Tests Log in to see 11 to 13 Days
96 Tests Log in to see 11 to 13 Days

More ELISA Kits for MEST Interaction Partners

Mouse (Murine) Mesoderm Specific Transcript (MEST) interaction partners

  1. Although both Mest and miR (show MLXIP ELISA Kits)-335 are highly expressed during muscle development and regeneration, only Mest+/- (maternal/paternal) mice show retardation of body growth.

  2. The paternally expressed imprinted gene Mest was only detected in haploid androgenetic blastocysts and was significantly lower in this group relative to the controls, indicating that the gene maintains expression patterns specific to its parental origin.

  3. analysis of modifications of H3 histone (show HIST1H3B ELISA Kits) in H19 (show NCKAP1 ELISA Kits) and MEST imprinted genes in blastocysts produced in vitro from non-vitrified and vitrified two-cell embryos

  4. Results suggest that at least one allele of Mest expression is required in the somatic tissues of adult individuals and that under certain conditions (such as in the presence of a Mest insertional mutation or in an altered genetic background), somatically acquired alterations of allelic expression at the Mest locus may occur.

  5. The data showed that Mest expression was regulated through cAMP-dependent protein kinase A pathways during differentiation of preadipocytes into adipocytes in vitro, supporting the critical role of Mest in proliferation and differentiation of adipocytes.

  6. The identification of new imprinted RNA products at the Mest locus, longer variants of the RNA, called MestXL, transcribed >10 kb into the downstream antisense gene Copg2 (show COPG2 ELISA Kits).

  7. Mest/Peg1 is a novel down-regulator of Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) signalling during adipogenic differentiation.

  8. Mest/Peg1 gene is imprinted, with preferential expression from the paternal allele.

  9. These data suggest that mechanisms independent of the CpG methylation status of the Mest promoter must underlie the control of its expression during adipose tissue expansion.

  10. MEST, a gene with a putative mesenchymal cell-derived protein, conceivably plays a role in mammalian metanephric development

Human Mesoderm Specific Transcript (MEST) interaction partners

  1. altered DNA methylation (show HELLS ELISA Kits) at imprinted domains including IGF2/H19 (show NCKAP1 ELISA Kits) and PEG1/MEST may mediate the association between human papillomavirus infection and invasive cervical cancer

  2. The expression levels of miR (show MLXIP ELISA Kits)-335 significantly correlated with those of MEST, supporting the notion that the intronic miR (show MLXIP ELISA Kits)-335 is co-expressed with its host gene

  3. DNA methylation (show HELLS ELISA Kits) level at the H19 (show NCKAP1 ELISA Kits) and MEST differentially methylated regions (DMRs)is reduced in placentas from pregnancies conceived by IVF (show SCN5A ELISA Kits)/ICSI when compared with placentas from spontaneous conception.

  4. Paternal methylation aberrations at imprinting control regions of DLK1 (show DLK1 ELISA Kits)-GTL2, MEST (PEG1), and ZAC (PLAGL1 (show PLAGL1 ELISA Kits)) and global methylation levels are not associated with idiopathic recurrent spontaneous miscarriages.

  5. Data indicate that ARMCX2 (show ARMCX2 ELISA Kits), COL1A1 (show COL1A1 ELISA Kits), MDK (show MDK ELISA Kits), MEST and MLH1 (show MLH1 ELISA Kits) genes acquired methylation in drug-resistant ovarian cancer-sustaining (side population) cells.

  6. MEST showed tissue-specific imprinting, being paternally expressed in skeletal muscle, fat, pituitary gland, heart, kidney, lung, stomach and uterus, and maternally expressed in spleen and liver.

  7. In cortices, the MEST promoter was hemimethylated, as expected for a differentially methylated imprinting control region, whereas the COPG2 and TSGA14 promoters were completely demethylated, typical for transcriptionally active non-imprinted genes.

  8. Regardless of conception method, the PEG1 methylation percentage in chorionic villus from spontaneous abortions is significantly higher than in villus from induced abortions and multifetal reduction.

  9. data demonstrated that tumorigenesis of leiomyoma is associated with overexpression of isoform 1 of PEG1/MEST gene, but not with loss of imprinting of the gene

  10. MEST gene is imprinted in an isoform-specific manner in adult lymphocytes.

MEST Antigen Profile

Antigen Summary

This gene encodes a member of the alpha/beta hydrolase superfamily. It is imprinted, exhibiting preferential expression from the paternal allele in fetal tissues, and isoform-specific imprinting in lymphocytes. The loss of imprinting of this gene has been linked to certain types of cancer and may be due to promotor switching. The encoded protein may play a role in development. Alternatively spliced transcript variants encoding multiple isoforms have been identified for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3 and 4, and the long arm of chromosomes 6 and 15.

Gene names and symbols associated with MEST

  • mesoderm specific transcript (Mest) antibody
  • mesoderm specific transcript (MEST) antibody
  • mesoderm specific transcript homolog (mouse) (MEST) antibody
  • AA408879 antibody
  • AI256745 antibody
  • PEG1 antibody

Protein level used designations for MEST

mesoderm-specific transcript protein , paternally-expressed gene 1 protein , mesoderm specific transcript homolog , mesoderm-specific transcript homolog protein

17294 Mus musculus
58827 Rattus norvegicus
4232 Homo sapiens
607717 Canis lupus familiaris
404180 Bos taurus
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