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MBD3L2 encodes a protein that is related to methyl-CpG-binding proteins but lacks the methyl-CpG binding domain. Additionally we are shipping Methyl-CpG Binding Domain Protein 3-Like 2 Proteins (2) and many more products for this protein.
Showing 10 out of 22 products:
Human Polyclonal MBD3L2 Primary Antibody for EIA, WB - ABIN953334
Jin, Jiang, Rauch, Li, Pfeifer: MBD3L2 interacts with MBD3 and components of the NuRD complex and can oppose MBD2-MeCP1-mediated methylation silencing. in The Journal of biological chemistry 2005
Show all 2 references for ABIN953334
MBD3L2 is more effective than MBD3 (show MBD3 Antibodies) in promoting Tet2 (show TET2 Antibodies) enzymatic activity through strengthening the binding affinity between Tet2 (show TET2 Antibodies) and the methylated DNA target.
These factors lead to a binding affinity hierarchy of p66alpha (show GATAD2A Antibodies) for the different MBD2 (show DPEP2 Antibodies) homologues (MBD2 (show DPEP2 Antibodies) approximately MBD3 (show MBD3 Antibodies) > MBD3L1 (show MBD3L1 Antibodies) approximately MBD3L2).
MBD3L2 interacts with MBD3 (show MBD3 Antibodies) and components of the NuRD complex and can oppose MBD2 (show DPEP2 Antibodies)-MeCP1-mediated methylation silencing
This gene encodes a protein that is related to methyl-CpG-binding proteins but lacks the methyl-CpG binding domain. The protein has been found in germ cell tumors and some somatic tissues.
MBD3-like protein 2
, methyl-CpG-binding domain protein 3-like 2