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MEX3C encodes a member of a family of proteins with two K homology (KH) RNA-binding domains and a C-terminal RING-finger domain. Additionally we are shipping MEX3C Antibodies (40) and many more products for this protein.
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associates with cytoplasmic deadenylation complexes and ubiquitinates CNOT7 (show CNOT7 Proteins)
The RNA-binding E3 ubiquitin ligase MEX-3C links ubiquitination with MHC-I mRNA degradation
In combination sibling-pair linkage analysis and case-control association studies of chromosome 18, RKHD2 is found to contribute to the genetic susceptibility of essential hypertension.
Data indicate that Mex3c mutation significantly increases physical activity.
MEX3C is required for cytokine production after infection with RNA viruses that are detected by RIG-I (show DDX58 Proteins).
Mex3c mutation caused leanness in both heterozygous and homozygous transgenic mice, as well as a more beneficial blood glucose and lipid profile in homozygous transgenic mice, in both sexes; data show Mex3c is involved in energy balance regulation
data suggest that MEX3C plays an important role in enhancing the translation of Igf1 (show IGF1 Proteins) mRNA directly or indirectly and promoting postnatal growth
This gene encodes a member of a family of proteins with two K homology (KH) RNA-binding domains and a C-terminal RING-finger domain. The protein interacts with mRNA via the KH domains, and the protein shuttles between the nucleus and cytoplasm. Polymorphisms in this gene may contribute to hypertension.
RNA-binding protein MEX3C
, ring finger and KH domain containing 2
, mex-3 homolog C (C. elegans)
, mex-3 homolog C
, RING finger and KH domain-containing protein 2
, RING finger protein 194
, RNA-binding E3 ubiquitin-protein ligase MEX3C