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The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, several of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. Additionally we are shipping and Microsomal Glutathione S-Transferase 2 Kits (1) and many more products for this protein.
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Human Monoclonal MGST2 Primary Antibody for IP, ELISA - ABIN517924
Yang, Lou: Sodium nitroprusside decreased leukotriene C4 generation by inhibiting leukotriene C4 synthase expression and activity in hepatic ischemia-reperfusion injured rats. in Biochemical pharmacology 2007
Show all 2 references for ABIN517924
Human Polyclonal MGST2 Primary Antibody for ICC, IF - ABIN4334184
Dvash, Har-Tal, Barak, Meir, Rubinstein: Leukotriene C4 is the major trigger of stress-induced oxidative DNA damage. in Nature communications 2015
Chicken Polyclonal MGST2 Primary Antibody for IHC, WB - ABIN2773859
Sjöström, Jakobsson, Heimburger, Palmblad, Haeggström: Human umbilical vein endothelial cells generate leukotriene C4 via microsomal glutathione S-transferase type 2 and express the CysLT(1) receptor. in European journal of biochemistry / FEBS 2001
Trimeric microsomal protein MGST2 displays one third of the sites reactivity.
characterized the substrate specificity and catalytic properties of purified MGST2 by steady-state and pre-steady-state kinetic experiments
A large Chinese sample of psoriasis did not provide any supporting evidence for MGST2 to be the psoriasis susceptibility gene within the PSORS9 locus.
The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, several of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. This gene encodes a protein which catalyzes the conjugation of leukotriene A4 and reduced glutathione to produce leukotriene C4. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
microsomal glutathione S-transferase 2
, microsomal GST-2
, microsomal GST-II