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anti-Microsomal Triglyceride Transfer Protein (MTTP) Antibodies

MTP encodes the large subunit of the heterodimeric microsomal triglyceride transfer protein. Additionally we are shipping MTTP Kits (24) and MTTP Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MTTP 17777 O08601
MTTP 310900  
MTTP 4547 P55157
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Top anti-MTTP Antibodies at antibodies-online.com

Showing 10 out of 45 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-MTTP Antibody Titration: 0.2-1 ug/mlPositive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry analysis of human hepatocarcinoma (Formalin-fixed, Paraffin-embedded) using MTTP Antibody (C-term), followed by peroxidase-conjugated secondary antibody and DAB staining. This data demonstrates the use of this antibody for IHC. Clinical relevance has not been evaluated. Western blot analysis of MTTP (arrow) in Hela, 293 cell line lysates (35ug/lane) using MTTP Antibody (C-term). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Mouse Mouse Un-conjugated IF, WB Western blot analysis of MTP on a mouse liver lysate. Lane 1: 1:2500, lane 2: 1:5000, lane 3: 1:10,000 dilution of the mouse anti-MTP antibody. 50 μg Log in to see 5 to 6 Days
$205.42
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of MTTP Antibody (C-term) (ABIN653011) in Hela, 293 cell line lysates (35 µg/lane). MTTP (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human hepatocarcinoma with MTTP Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$369.79
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 8 to 10 Days
$449.17
Details
Mouse Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of 293 cell lines, using MTTP antibody. Immunofluorescence analysis of U20S cell using MTTP antibody. Blue: DAPI for nuclear staining. 100 μL Log in to see 9 Days
$302.50
Details
Human Rabbit Un-conjugated WB MTTP antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details

MTTP Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,
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Rat (Rattus)
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Human , ,
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Top referenced anti-MTTP Antibodies

  1. Mouse (Murine) Monoclonal MTTP Primary Antibody for IF, WB - ABIN968716 : Chen, Newberry, Norris, Xie, Luo, Kennedy, Davidson: ApoB100 is required for increased VLDL-triglyceride secretion by microsomal triglyceride transfer protein in ob/ob mice. in Journal of lipid research 2008 (PubMed)
    Show all 6 references for ABIN968716

  2. Human Polyclonal MTTP Primary Antibody for EIA, IHC (p) - ABIN953540 : Dai, Khatun, Hussain: NR2F1 and IRE1beta suppress microsomal triglyceride transfer protein expression and lipoprotein assembly in undifferentiated intestinal epithelial cells. in Arteriosclerosis, thrombosis, and vascular biology 2010 (PubMed)
    Show all 2 references for ABIN953540

  3. Chicken Polyclonal MTTP Primary Antibody for WB - ABIN2781495 : Lundahl, Skoglund-Andersson, Caslake, Bedford, Stewart, Hamsten, Packard, Karpe: Microsomal triglyceride transfer protein -493T variant reduces IDL plus LDL apoB production and the plasma concentration of large LDL particles. in American journal of physiology. Endocrinology and metabolism 2006 (PubMed)

More Antibodies against MTTP Interaction Partners

Fruit Fly (Drosophila melanogaster) Microsomal Triglyceride Transfer Protein (MTTP) interaction partners

  1. promotes assembly and secretion of human apolipoprotein B (show APOB Antibodies)

  2. the phospholipid transfer activity of MTP is sufficient for the assembly and secretion of primordial apoB (show APOB Antibodies) lipoproteins

Zebrafish Microsomal Triglyceride Transfer Protein (MTTP) interaction partners

  1. analysis of developmental expression and nutritional regulation of zebrafish homolog to mammalian microsomal triglyceride transfer protein large subunit

  2. In a genetic study of lipid transport and metabolism, larval levels of microsomal triglyceride transfer protein (Mtp), the protein responsible for packaging triacylglycerol and beta-lipoproteins into lipoprotein particles, are unchanged by feeding.

Pig (Porcine) Microsomal Triglyceride Transfer Protein (MTTP) interaction partners

  1. MTTP is regulated by apo A-IV in manner to promote increased packaging of triglyceride into chylomicron core, which may be important in neonatal fat absorption.

  2. There appears to be an interaction between the porcine MTTP genotype and the type of fat source in the pig diet, which would agree with the previous results on the biology of MTTP biology.

Cow (Bovine) Microsomal Triglyceride Transfer Protein (MTTP) interaction partners

  1. Nonesterified fatty acids significantly inhibit the expression of ApoB100 (show APOB Antibodies), ApoE (show APOE Antibodies), MTP, and LDLR (show LDLR Antibodies), thereby decreasing the synthesis and assembly of VLDL and inducing TG accumulation in bovine hepatocytes.

  2. after calving the apolipoprotein B(100 (show APOB Antibodies)) mRNA synthesis was lower, whereas microsomal triglyceride transfer protein (MTP) and apolipoprotein E (show APOE Antibodies) messenger RNA abundance were higher in the liver

  3. measurements of the transfer of phospholipids (PLs (show CTSC Antibodies)) and cholesteryl esters (CEs)to acceptor vesicles by purified MTP showed TAG transfer activity was the most robust, and CE and PL transfer activities were 60-71% and 5-13% of the TAG transfer activity

Mouse (Murine) Microsomal Triglyceride Transfer Protein (MTTP) interaction partners

  1. The results suggest that physiologic hepcidin (show HAMP Antibodies) levels are insufficient to alter Fpn levels within the retinal pigment epithelium and Muller cells, but may limit iron transport into the retina from vascular endothelial cells.

  2. PHARMACOLOGICAL STUDY OF NEW COMPOUNDS ACTING AS REGULATORS OF 18-KDA TRANSLOCATOR PROTEIN (show TSPO Antibodies) LIGANDS

  3. In Angiotensin II treated mice, duodenal divalent metal transporter-1 (show SLC11A2 Antibodies) and ferroportin (show SLC40A1 Antibodies) expression levels were increased and hepatic hepcidin (show HAMP Antibodies) mRNA expression and serum hepcidin (show HAMP Antibodies) concentration were reduced.

  4. Intestine-specific MTP (show LAPTM4A Antibodies) and global ACAT2 (show SOAT2 Antibodies) deficiency lowers acute cholesterol absorption with chylomicrons and HDLs (show CSF1R Antibodies)

  5. Mice infected with Salmonella typhimurium have increased duodenal expression of the iron exporter ferroportin-1 (show SLC40A1 Antibodies), consistent with increased uptake of dietary iron.

  6. Results suggest that reduction in ferroportin (show SLC40A1 Antibodies) levels in Alzheimer's disease brains are likely associated with cerebral ischaemia, inflammation, loss of neurons due to protein misfolding, senile plaque formation and possibly ageing process itself

  7. intestine-specific Mttp deletion is beneficial in young septic mice but harmful in aged mice

  8. identified microsomal triglyceride transfer protein, which we show is also under the transcriptional regulation of C/EBPbeta (show CEBPB Antibodies) and -delta, as a novel player in the presentation of endogenous lipid antigens by adipocytes

  9. effects of reducing either systemic or liver-specific MTP (show LAPTM4A Antibodies) activity on cholesterol metabolism and reverse cholesterol transport

  10. Data show that combined deletion of microsomal triglyceride transfer protein (Mttp) and liver fatty acid binding protein 1 (L-Fabp (show FABP1 Antibodies)) are protected from lithogenic diet (LD)-induced gallstone formation.

Human Microsomal Triglyceride Transfer Protein (MTTP) interaction partners

  1. the N-terminal domain of MTP is important for its lipid transfer activity

  2. These studies indicated that SAP18 (show SAP18 Antibodies) expression enhanced the recruitment of mSin3A in coordination with TRIB1 (show TRIB1 Antibodies) to MTTP regulatory elements and increased MTTP expression.

  3. Results present evidence that MTTP polymorphisms could modulate the lipid homeostasis to determine the serum lipids and increase risk of non-alcoholic fatty liver disease.

  4. Findings from meta-analysis indicate that the MTP -493G/T polymorphism may contribute to the development of non-alcoholic fatty liver disease. Thus, the MTP -493G/T polymorphism may be a biomarker for the early detection of the disease.

  5. Homozygous MTTP mutations may lead to hepatic steatosis and fibrosis despite metabolic differences in congenital hypocholesterolemia.

  6. MTTP SNPs (GG, GT, TT) and alleles (G, T) in the chronic hepatitis C (genotype 4) patients versus the uninfected controls were 70%, 21%, 9% & 80.5%, 19.5% versus 10%, 87.5%, 2.5% & 53.8%, 46.3%, respectively (p=0.0001).

  7. The MTP-493G/T polymorphism modulates postprandial apoB48 and apoB100 (show APOB Antibodies) of triglyceride-rich lipoproteins in familial combined hyperlipidemia

  8. Case Reports: novel mutation in MTTP gene responsible for abetalipoproteinemia in Tunisian families.

  9. Report of two new mutations of MTTP, a nonsense mutation c.2313T > A leading to a truncated protein (p.Y771X) and a splice mutation IVS 9 + 2T > G, in abetalipoproteinemia

  10. MTTP genetic polymorphisms influence the susceptibility to developing NAFLD in the Han Chinese population.

MTTP Antigen Profile

Protein Summary

MTP encodes the large subunit of the heterodimeric microsomal triglyceride transfer protein. Protein disulfide isomerase (PDI) completes the heterodimeric microsomal triglyceride transfer protein, which has been shown to play a central role in lipoprotein assembly. Mutations in MTP can cause abetalipoproteinemia.

Gene names and symbols associated with MTTP

  • Microsomal triacylglycerol transfer protein (Mtp) antibody
  • microsomal triglyceride transfer protein (mtp) antibody
  • microsomal triglyceride transfer protein (MTTP) antibody
  • microsomal triglyceride transfer protein (Mttp) antibody
  • mitochondrially encoded tRNA proline (MT-TP) antibody
  • solute carrier family 40 (iron-regulated transporter), member 1 (Slc40a1) antibody
  • 1810043K16Rik antibody
  • ABL antibody
  • CG9342 antibody
  • CT3751 antibody
  • Dmel\\CG9342 antibody
  • dMTP antibody
  • Dusg antibody
  • Fpn1 antibody
  • IREG1 antibody
  • MTP antibody
  • MTP1 antibody
  • MTTP antibody
  • Ol5 antibody
  • Pcm antibody
  • Slc11a3 antibody
  • Slc39a1 antibody
  • wu:fd36b01 antibody
  • zgc:111876 antibody

Protein level used designations for MTTP

microsomal triacylglycerol transfer protein , CG9342-PA , Mtp-PA , microsomal triglyceride transfer protein , microsomal triglyceride transfer protein large subunit , stalactite , stl , microsomal triglyceride transfer protein (large polypeptide, 88kDa) , microsomal triglyceride transfer protein B , microsomal triglyceride transfer protein, large subunit , SLC11A3 iron transporter , duodenal-specific , ferroportin 1 , ferroportin-1 , iron-regulated transporter 1 , metal transporter protein 1 , metal transporting protein 1 , polycythaemia , solute carrier family 11 (proton-coupled divalent metal ion transporters), member 3 , solute carrier family 39 (iron-regulated transporter), member 1 , solute carrier family 40 member 1

GENE ID SPECIES
35362 Drosophila melanogaster
406207 Danio rerio
471397 Pan troglodytes
422709 Gallus gallus
487873 Canis lupus familiaris
397381 Sus scrofa
280868 Bos taurus
17777 Mus musculus
310900 Rattus norvegicus
4547 Homo sapiens
100734244 Cavia porcellus
100341961 Oryctolagus cuniculus
101110939 Ovis aries
101836921 Mesocricetus auratus
4571 Homo sapiens
53945 Mus musculus
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