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involved in the O-acetylation of GD3 ganglioside sialic acid [RGD, Feb 2006].. Additionally we are shipping MFGE8 Kits (38) and MFGE8 Proteins (30) and many more products for this protein.
Showing 10 out of 149 products:
Mouse (Murine) Monoclonal MFGE8 Primary Antibody for IHC (fro), WB - ABIN1449223
Kranich, Krautler, Heinen, Polymenidou, Bridel, Schildknecht, Huber, Kosco-Vilbois, Zinkernagel, Miele, Aguzzi: Follicular dendritic cells control engulfment of apoptotic bodies by secreting Mfge8. in The Journal of experimental medicine 2008
Show all 5 references for ABIN1449223
Mouse (Murine) Monoclonal MFGE8 Primary Antibody for FACS, IP - ABIN1449192
Fens, Mastrobattista, de Graaff, Flesch, Ultee, Rasmussen, Molema, Storm, Schiffelers: Angiogenic endothelium shows lactadherin-dependent phagocytosis of aged erythrocytes and apoptotic cells. in Blood 2008
Show all 4 references for ABIN1449192
Human Polyclonal MFGE8 Primary Antibody for FACS, WB - ABIN656815
Yamaguchi, Fujimoto, Nakamura, Ohmura, Mimori, Matsuda, Nagata: Aberrant splicing of the milk fat globule-EGF factor 8 (MFG-E8) gene in human systemic lupus erythematosus. in European journal of immunology 2010
Show all 2 references for ABIN656815
Human Monoclonal MFGE8 Primary Antibody for EIA, IHC (fro) - ABIN112407
Bártková, Rejthar, Bártek, Kovarík: Differentiation patterns of testicular germ-cell tumours as revealed by a panel of monoclonal antibodies. in Tumour biology 1987
Show all 2 references for ABIN112407
Human Monoclonal MFGE8 Primary Antibody for FACS, WB - ABIN4899815
Jinushi, Nakazaki, Carrasco, Draganov, Souders, Johnson, Mihm, Dranoff: Milk fat globule EGF-8 promotes melanoma progression through coordinated Akt and twist signaling in the tumor microenvironment. in Cancer research 2008
an efficient purification method for production of non-aggregated, full-length MFG-E8.
Reduced serum milk fat globule-epidermal growth factor (show EGF Antibodies) 8 (MFG-E8) concentrations are associated with an increased risk of microvascular complications in patients with type 2 diabetes.
MFG-E8 is a protective factor in the pathogenesis of rheumatoid arthritis and subsequent bone loss.
After myocardial infarction, Mfge8 (and Mertk (show MERTK Antibodies))-expressing macrophages synergistically engage the clearance of injured cardiomyocytes.
MFG-E8 promotes cutaneous wound healing by enhancing angiogenesis.
Lactadherin may decrease inflammation by inhibiting secretory phospholipase A2 (show YWHAZ Antibodies) activity on pre-apoptotic leukemia cells.
MFG-E8 had a negative association with hs-CRP (show CRP Antibodies) and a positive association with LDL-c. The serum level of MFG-E8 was negatively associated with the severity of coronary artery stenosis and the risk of clinical events.
medin adopts a predominantly beta-sheet conformation with some unstructured elements.
MFG-E8 could be used as a biomarker for diagnosis and monitoring of disease activity in certain systemic lupus erythematosus patients
Exogenously added MFG-E8 inhibits receptor activ (show TNFSF11 Antibodies)ator NF-kappaB ligand-induced osteoclastogenesis of human osteoclast precursors.
The vesicular environment provides optimal conditions for presentation and recognition of phosphatidylserine by lactadherin in a simple binding mechanism.
lactophorin C-terminal fragment (LP16) and bovine milk fat globule membrane protein PAS6/7 strongly inhibited the replication of human rotavirus replication
Lactadherin inhibits enzyme complexes of blood coagulation by competing for phospholipid-binding sites.
The number of lactadherin binding sites increased proportionally to the phosphatidylserine content over a range 0-2% and less rapidly for higher phosphatidylserine content
The crystal structure of the bovine lactadherin C2 domain (residues 1 to 158) at 2.4 A, was determined.
angiogenic endothelial cells have phagocytic properties for lactadherin-opsonized large particles and apoptotic cells
Milk fat globule-epidermal growth factor (show EGF Antibodies)-factor VIII downregulates interleukin-17 (show IL17A Antibodies) expression in sepsis by modulating STAT3 (show STAT3 Antibodies) activation.
Data indicate that Sp1 (show SP1 Antibodies) and AP-1 (show JUN Antibodies)-related factors are involved in the regulation of MFG-E8 gene transcription by targeting their binding sites in the 5'-flanking region under physiological and inflammatory states.
MFG-E8 promotes tumor growth regardless of the presence or absence of colonic inflammation, whereas colon tumor development is initiated by MFG-E8 under inflammatory conditions.
The MFG-E8 in breast milk may mask the phosphatidylserine exposed on the surface of mik fat globules(MFGs) with time after secretion and thereby suppress the membrane fusion among MFGs resulting in the enlargement of MFGs in the breast milk.
data indicate that MFG-E8 controls steady-state and pathological bone turnover and may therefore represent a new target gene in the treatment of bone diseases
MFG-8 is expressed in fetal hematopoietic stem cells populations, and MFG-E8 may have a role in embryonic hematopoiesis.
increased TGFbeta1 (show TGFB1 Antibodies) expression in models of neurodegeneration might be involved in clearance of apoptotic cells via regulation of Milk fat globule-epidermal growth factor (show EGF Antibodies)-factor 8 expression
MFG-E8 may inhibit the formation of pressure ulcers induced by cutaneous I/R injury by regulating angiogenesis and inflammation
The evidence suggests that lactadherin and the other F4-binding milk proteins, together with other defense components of milk, could play a role in protection of neonatal piglets against ETEC induced diarrhea.
involved in the O-acetylation of GD3 ganglioside sialic acid
milk fat globule-EGF factor 8 protein
, sperm-membrane associated protein P47
, O-acetyl disialoganglioside synthase
, breast epithelial antigen BA46
, sperm associated antigen 10
, sperm surface protein hP47
, PAS-6/PAS-7 glycoprotein
, components 15/16
, sperm surface protein SP47
, EGF/factor VIII
, milk fat globule glycoprotein
, O-acetyl GD3 ganglioside synthase
, O-acetyltransferase Milk fat glolbule membrane protein
, O-acetyltransferase milk fat globule membrane protein
, milk fat globule EGF factor 8 protein
, pP47 protein