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Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Additionally we are shipping Mitochondrial Ribosomal Protein L19 Antibodies (47) and Mitochondrial Ribosomal Protein L19 Kits (8) and many more products for this protein.
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MRPL19 was initially implicated in dyslexia through family-based studies.
study failed to show any association of MRPL19 SNPs with developmental dyslexia in an Indian population.
Study refined the 2p12 candidate region in two populations and report evidence supporting MRPL19 and C2ORF3 as candidate susceptibility genes for dyslexia.
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein.
39S ribosomal protein L19, mitochondrial
, ribosomal protein, mitochondrial, L15
, 39S ribosomal protein L15, mitochondrial