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Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Additionally we are shipping Mitochondrially Encoded NADH Dehydrogenase 5 Antibodies (59) and Mitochondrially Encoded NADH Dehydrogenase 5 Proteins (4) and many more products for this protein.
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FASTKD4 (show TBRG4 ELISA Kits) is required to promote expression of ND5. FASTKD4 (show TBRG4 ELISA Kits) may promote processing of ND5-CYB (show CSTB ELISA Kits) precursor or it may stabilize multiple mature RNAs including ND5.
The m.13565C>T mutation in MTND5 causes defects in both mitochondrial oxidative metabolism and mitochondrial calcium sequestration in a MELAS syndrome fibroblasts.
Mitochondrially encoded NADH dehydrogenase subunit, complex I extracts energy from NADH, produced by the oxidation of sugars and fats, and traps the energy in a potential difference or voltage across the mitochondrial inner membrane.
Study demonstrates a link between p53 (show TP53 ELISA Kits) and Bcl-2 (show BCL2 ELISA Kits) proteins as regulators of ROS (show ROS1 ELISA Kits) production and cellular invasiveness, and reveals complex-I, especially ND5, as their functional target in lung tumor cells.
Three mutations were significantly related to the presence of epilepsy. These mutations were found at the 8502, 11994, and 13,231 bp of mtDNA, which resulted in amino acid changes at the MT-ATP-8 (show MT-ATP8 ELISA Kits), MT-ND4 (show MT-ND4 ELISA Kits) and MT-ND5 genes.
Point mutations m.10191T>C in mitochondrial ND3 (show MT-ND3 ELISA Kits) gene, m.13513G>A in ND5 gene and m.14,453G>A in ND6 (show MT-ND6 ELISA Kits) gene were detected in three Chinese children with Leigh synrome dur to complex I deficiency.
Mitochondrial ND5 12338T>C variant is associated with maternally inherited hypertrophic cardiomyopathy in a Chinese pedigree
Mitochondrial DNA mutations in respiratory complex-I in never-smoker lung cancer patients contribute to lung cancer progression in association with EGFR (show EGFR ELISA Kits) gene mutation.
ND4 (show MT-ND4 ELISA Kits) G11696A and ND5 T12338C mutation is likely associated with Leber's hereditary optic neuropathy in two Chinese families
Patients with ND5*13513 G to A mutation may have a characteristic clinical course and ND5 *13513 G to A might be a preferential candidate mutation of Leigh syndrome.
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
NADH dehydrogenase subunit 5