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This protein is expressed by in vitro differentiated macrophages but not freshly isolated monocytes. Additionally we are shipping MMD Kits (6) and and many more products for this protein.
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high PAQR11 levels were correlated with epithelial-to-mesenchymal transition (EMT (show ITK Proteins)) and shorter survival in human cancers, and PAQR11 was found to be essential for tumor cell migration and metastasis in EMT (show ITK Proteins)-driven lung adenocarcinoma models.
Together, our results highlight the significance of miR-140-5p/MMD axis in lung cancer, and miR-140-5p/MMD axis could serve as new molecular targets for the therapy against lung cancer.
this study uncovers a new paradigm of spatial regulation of Ras signaling in the Golgi apparatus by PAQR10 (show MMD2 Proteins) and PAQR11.
These results suggested that MMD modulates TNF-alpha (show TNF Proteins) and NO production in macrophages, and this process might involves Erk (show EPHB2 Proteins) or Akt (show AKT1 Proteins).
This protein is expressed by in vitro differentiated macrophages but not freshly isolated monocytes. Although sequence analysis identifies seven potential transmembrane domains, this protein has little homology to G-protein receptors and it has not been positively identified as a receptor. A suggested alternative function is that of an ion channel protein in maturing macrophages.
monocyte to macrophage differentiation-associated
, macrophage maturation-associated
, monocyte to macrophage differentiation factor
, monocyte to macrophage differentiation protein
, progestin and adipoQ receptor family member 11
, progestin and adipoQ receptor family member XI
, macrophage/microglia activation-associated factor