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Mov10l1, Moloney Leukemia Virus 10-Like 1, Homolog (Mouse) Proteins (MOV10L1)

MOV10L1 is similar to a mouse gene that encodes a putative RNA helicase and shows testis-specific expression. Additionally we are shipping MOV10L1 Antibodies (14) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MOV10L1 83456 Q99MV5
MOV10L1 54456 Q9BXT6
Rat MOV10L1 MOV10L1 300141  
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Top MOV10L1 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

MOV10L1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,

More Proteins for Mov10l1, Moloney Leukemia Virus 10-Like 1, Homolog (Mouse) (MOV10L1) Interaction Partners

Mouse (Murine) Mov10l1, Moloney Leukemia Virus 10-Like 1, Homolog (Mouse) (MOV10L1) interaction partners

  1. Mutations in the conserved ATP hydrolysis motif of MOV10L1 block piRNA biogenesis and result in male sterility.

  2. MOV10L1 exhibits 5'-to-3' directional RNA-unwinding activity in vitro and its RNA helicase activity is required for primary piRNA biogenesis in vivo. MOV10L1 selectively binds piRNA precursor transcripts. MOV10L1 is essential for the generation of intermediate piRNA processing fragments. piRNA precursor processing is intimately coupled with elements of local secondary structures such as G quadruplexes.

  3. MOV10L1 is essential for the primary processing of pachytene piRNAs. MOV10L1 acts upstream of PIWI proteins in the piRNA pathway and is a master regulator of the piRNA biogenesis.

  4. Mov10l1 mutant males are sterile owing to complete meiotic arrest. This mutant expresses Piwi proteins but lacks piRNAs, suggesting that MOV10L1 is required for piRNA biogenesis and/or loading to Piwi proteins.

  5. studies reveal a crucial role of MOV10L1 in male fertility and piRNA-directed retrotransposon silencing in male germ cells and suggest that MOV10L1 functions as a key component of a safeguard mechanism for the genetic information in male germ cells

  6. expression in oocytes sensitive to TAF4B level

  7. CHAMP acts as an inhibitor of cell proliferation and cardiomyocyte hypertrophy.

  8. Nkx2.5 (show NKX2-5 Proteins) transactivates the Csm promoter, suggesting that Nkx2.5 (show NKX2-5 Proteins) is essential for embryonic Csm (cardiac-specific isoform of Mov10l1) expression

Human Mov10l1, Moloney Leukemia Virus 10-Like 1, Homolog (Mouse) (MOV10L1) interaction partners

  1. Our results suggest that MOV10L1 gene polymorphisms in the studied infertile males with complete maturation arrest are linked to infertility.

MOV10L1 Protein Profile

Protein Summary

This gene is similar to a mouse gene that encodes a putative RNA helicase and shows testis-specific expression. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with MOV10L1

  • Mov10l1, Moloney leukemia virus 10-like 1, homolog (mouse) (MOV10L1)
  • Mov10l1, Moloney leukemia virus 10-like 1, homolog (mouse) (mov10l1)
  • Moloney leukemia virus 10-like 1 (Mov10l1)
  • Mov10l1, Moloney leukemia virus 10-like 1, homolog (mouse) (Mov10l1)
  • CHAMP protein
  • Csm protein
  • DJ402G11.8 protein

Protein level used designations for MOV10L1

Mov10l1, Moloney leukemia virus 10-like 1, homolog (mouse) , Mov10l1-like protein , MOV10-like 1 , putative helicase Mov10l1-like , MOV10-like protein 1 , cardiac helicase activated by MEF2 protein , cardiac-specific RNA helicase , moloney leukemia virus 10-like protein 1 , putative helicase Mov10l1 , Mov10-like 1 , cardiac helicase activated by MEF2C protein , Moloney leukemia virus 10-like 1 , Mov10l1, Moloney leukemia virus 10-like 1, homolog

GENE ID SPECIES
100056030 Equus caballus
100083059 Ornithorhynchus anatinus
100139822 Bos taurus
100351875 Oryctolagus cuniculus
100519488 Sus scrofa
100539488 Meleagris gallopavo
100565506 Anolis carolinensis
83456 Mus musculus
54456 Homo sapiens
474460 Canis lupus familiaris
300141 Rattus norvegicus
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