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May play a role in the cell adhesion to the extracellular matrix.. Additionally we are shipping MUC15 Antibodies (43) and MUC15 Kits (7) and many more products for this protein.
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Frameshift mutations of MUC15 gene is associated with gastric and colorectal cancers.
Multivariate analysis suggested that MUC15 overexpression was an independent factor for prognosis (hazard risk: 3.216; P=0.009). It was concluded that MUC15 is overexpressed in glioma tissues.
MUC15 inhibits dimerization of EGFR (show EGFR Proteins) and PI3K (show PIK3CA Proteins)-AKT (show AKT1 Proteins) signaling and is associated with aggressive hepatocellular carcinomas in patients.
MUC15 is a strong candidate for eczema.
MUC4 (show MUC4 Proteins) and MUC15 were overexpressed in papillary thyroid carcinoma, and high MUC15 expression was associated with high malignant potential.
MUC15 was expressed most highly in human placenta. MUC15 mRNA & protein increased with gestational age (P < 0.05, 1st versus 3rd trimester). Differential expression of MUC15 in human placentas may play critical role in regulation of trophoblast invasion.
Reflux laryngitis is associated with down-regulation of mucin (show SLC13A2 Proteins) gene expression.
Overexpression of MUC15 activates extracellular signal-regulated kinase 1/2 (show MAPK3 Proteins) and promotes the oncogenic potential of colon cancer cells.
May play a role in the cell adhesion to the extracellular matrix.
mucin 15, cell surface associated
, cell surface associated mucin 15
, component II
, glycoprotein 4
, glycoprotein C