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anti-Myosin Heavy Chain 11, Smooth Muscle (MYH11) Antibodies

The protein encoded by MYH11 is a smooth muscle myosin belonging to the myosin heavy chain family. Additionally we are shipping MYH11 Kits (19) and MYH11 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MYH11 4629 P35749
MYH11 24582  
MYH11 17880  
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Top anti-MYH11 Antibodies at antibodies-online.com

Showing 10 out of 139 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated IF, IHC (p), WB   0.1 mg Log in to see 6 to 8 Days
$313.50
Details
Human Mouse Un-conjugated IHC (p) 0.1 mg Log in to see 10 to 12 Days
$496.65
Details
Cow Rabbit Un-conjugated IHC (fro), IF, WB   0.5 mL Log in to see 6 to 8 Days
$687.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   0.1 mg Log in to see 2 to 6 Days
$359.70
Details
Human Mouse Un-conjugated IHC (fro), IHC (p)   1 mL Log in to see 6 to 8 Days
$764.50
Details
Human Mouse Un-conjugated IHC (fro), IHC (p), WB   100 μg Log in to see 8 to 10 Days
$463.83
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$527.15
Details
Chicken Mouse Un-conjugated IHC (fro), IHC (p), WB   100 μg Log in to see 4 to 6 Days
$200.00
Details
Rat Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$418.00
Details
Mouse Rabbit Un-conjugated IHC, WB 200 μL Log in to see 9 Days
$588.50
Details

MYH11 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-MYH11 Antibodies

  1. Human Monoclonal MYH11 Primary Antibody for IHC (fro), IHC (p) - ABIN1108365 : Werling, Hwang, Yaziji, Gown: Immunohistochemical distinction of invasive from noninvasive breast lesions: a comparative study of p63 versus calponin and smooth muscle myosin heavy chain. in The American journal of surgical pathology 2002 (PubMed)
    Show all 4 references for ABIN1108365

  2. Human Monoclonal MYH11 Primary Antibody for IF, IHC (p) - ABIN1108366 : Deng, Liu, Marlton, Claxton, Lane, Callen, Collins, Siciliano: Smooth muscle myosin heavy chain locus (MYH11) maps to 16p13.13-p13.12 and establishes a new region of conserved synteny between human 16p and mouse 16. in Genomics 1994 (PubMed)
    Show all 2 references for ABIN1108366

  3. Human Polyclonal MYH11 Primary Antibody for IHC, ELISA - ABIN1585256 : Staus, Blaker, Medlin, Taylor, Mack: Formin homology domain-containing protein 1 regulates smooth muscle cell phenotype. in Arteriosclerosis, thrombosis, and vascular biology 2011 (PubMed)
    Show all 2 references for ABIN1585256

  4. Cow (Bovine) Polyclonal MYH11 Primary Antibody for IHC (fro), IF - ABIN318731 : Rosenfeld, Xing, Cheung, Brown, Kar, Sweeney: Structural and kinetic studies of phosphorylation-dependent regulation in smooth muscle myosin. in The Journal of biological chemistry 1998 (PubMed)

More Antibodies against MYH11 Interaction Partners

Human Myosin Heavy Chain 11, Smooth Muscle (MYH11) interaction partners

  1. Deletion mutation in MYH11 gene causing familial Thoracic aortic dissection was identified in two independent Japanese pedigrees.

  2. Data suggest that expression of MYH11, myosin light chain, and MLCK (myosin-light-chain kinase (show MYLK Antibodies)), is up-regulated in uterine myoma as compared to adjacent smooth muscle cells; expression of MYH11 appears to be involved in cell proliferation.

  3. In familial AAA (show APP Antibodies) we found one pathogenic and segregating variant (COL3A1 (show COL3A1 Antibodies) p.Arg491X), one likely pathogenic and segregating (MYH11 p.Arg254Cys), and fifteen VUS.

  4. CBFB (show CBFB Antibodies) contributes to the transcriptional regulation of ribosomal gene expression and provide further understanding of the epigenetic role of CBFB (show CBFB Antibodies)-SMMHC in proliferation and maintenance of the leukemic phenotype.

  5. we report a novel hypomethylation pattern, specific to CBFB-MYH11 fusion resulting from inv(16) rearrangement in acute myeloid leukemia the expression of which correlated with PBX3 differential methylation

  6. overexpression of MYH11 can lead to increased ER stress and autophagy

  7. MYH11 gene mutation is associated with family history of thoracic aortic aneurysm dissection.

  8. Transcriptional analysis revealed that upon fusion protein knockdown, a small subset of the CBFbeta (show CBFB Antibodies)-MYH11 target genes show increased expression, confirming a role in transcriptional repression

  9. MYH11 mutations are rare and are identified in patients with thoracic aortic aneurysm/dissection.

  10. Incomplete segregation of MYH11 variants with thoracic aortic aneurysms and dissections and patent ductus arteriosus.

Mouse (Murine) Myosin Heavy Chain 11, Smooth Muscle (MYH11) interaction partners

  1. Cbfbeta (show CBFB Antibodies)-SMMHC and Nras (show NRAS Antibodies)(G12D) promote the survival of preleukemic myeloid progenitors primed for leukemia by activation of the MEK (show MDK Antibodies)/ERK (show EPHB2 Antibodies)/Bim (show BCL2L11 Antibodies) axis, and define Nras (show NRAS Antibodies)(LSL-G12D); Cbfb (show CBFB Antibodies)(56M) mice as a valuable genetic model for the study of AML (show RUNX1 Antibodies) therapies.

  2. A rare variant in MYH11, R247C, alters myosin contractile function and smooth muscle cell phenotype, leading to increased proliferation in vitro and in response to vascular injury.

  3. Data show the cooperation between mutated KIT and CBFB (show CBFB Antibodies)-MYH11 during leukemogenesis

  4. Cbfb (show CBFB Antibodies)/Runx1 (show RUNX1 Antibodies) repression-independent activities contribute to leukemogenesis by Cbfb (show CBFB Antibodies)-MYH11

  5. Myh11 complexes with Cbfb (show CBFB Antibodies) and inhibits the cell cycle.

  6. report the identification of genes that specifically cooperate with CBFB (show CBFB Antibodies)-MYH11 in leukemogenesis

  7. Force dilatation pressure was decreased in smooth muscle B mysoin null mesenteric vessels. (Myosin B))

  8. provides a mechanistic basis for the myeloid-lineage bias of CBFbeta (show CBFB Antibodies)-SMMHC-associated leukemia

  9. Runx2 (show RUNX2 Antibodies) is expressed in the stem cell compartment, interferes with differentiation and represses CBF (show CEBPZ Antibodies) targets in the myeloid compartment, and modulates the leukemogenic function of Cbfbeta (show CBFB Antibodies)-SMMHC in mouse leukemia.

MYH11 Antigen Profile

Protein Summary

The protein encoded by this gene is a smooth muscle myosin belonging to the myosin heavy chain family. The gene product is a subunit of a hexameric protein that consists of two heavy chain subunits and two pairs of non-identical light chain subunits. It functions as a major contractile protein, converting chemical energy into mechanical energy through the hydrolysis of ATP. The gene encoding a human ortholog of rat NUDE1 is transcribed from the reverse strand of this gene, and its 3' end overlaps with that of the latter. The pericentric inversion of chromosome 16

Gene names and symbols associated with MYH11

  • myosin, heavy chain 11, smooth muscle (MYH11) antibody
  • myosin, heavy chain 11, smooth muscle (Myh11) antibody
  • myosin, heavy polypeptide 11, smooth muscle (Myh11) antibody
  • AAT4 antibody
  • AV071570 antibody
  • FAA4 antibody
  • myosin antibody
  • SM1 antibody
  • SM2 antibody
  • SMHC antibody
  • smMHC antibody

Protein level used designations for MYH11

myosin heavy chain 11 , myosin heavy chain, smooth muscle isoform , myosin, heavy polypeptide 11, smooth muscle , myosin-11 , myosin heavy chain SMA , SMMHC , myosin heavy chain 21 , smooth muscle myosin heavy chain , MHC , gizzard smooth muscle , heavy polypeptide 11 , myosin heavy chain, gizzard smooth muscle , smooth muscle , myosin heavy chain 11, smooth muscle

GENE ID SPECIES
4629 Homo sapiens
530050 Bos taurus
24582 Rattus norvegicus
396211 Gallus gallus
100009145 Oryctolagus cuniculus
17880 Mus musculus
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