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Myosin VIIA and Rab Interacting Protein Proteins (MYRIP)

Rab effector protein involved in melanosome transport. Additionally we are shipping MYRIP Antibodies (44) and MYRIP Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MYRIP 25924 Q8NFW9
MYRIP 245049 Q8K3I4
Rat MYRIP MYRIP 360034 Q7TNY7
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Top MYRIP Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 9 to 11 Days
$229.85
Details

MYRIP Proteins by Origin and Source

Origin Expressed in Conjugate
Human

Mouse (Murine)

More Proteins for Myosin VIIA and Rab Interacting Protein (MYRIP) Interaction Partners

Zebrafish Myosin VIIA and Rab Interacting Protein (MYRIP) interaction partners

  1. indicate that MyRIP functions as a scaffolding protein that links protein kinase A to components of the exocytosis machinery

Human Myosin VIIA and Rab Interacting Protein (MYRIP) interaction partners

  1. The role of MyRIP in Ca(2+)-driven exocytosis requires both MyoVa- and actin-binding potential.

  2. Myrip couples the retention of secretory granules in the cell cortex, their transport to the plasma membrane, and their attachment to the plasma membrane, thus promoting secretion.

  3. A Rab27a (show RAB27A Proteins)/MyRIP/myosin Va (show MYO5A Proteins) complex is involved in linking von-Willebrand factor (Vwf (show VWF Proteins)) to the peripheral actin cytoskeleton of endothelial cells to allow full maturation and prevent premature secretion of vWF (show VWF Proteins).

  4. A new potentially protective effect was identified at rs2679798 in MYRIP.

  5. a molecular complex composed of Rab27A, MyRIP and myosin VIIa bridges retinal melanosomes to the actin cytoskeleton and thereby mediates the local trafficking of these organelles

  6. Slac2c/MyRIP is part of a complex mediating the interaction of secretory granules with cortical actin cytoskeleton

  7. During primate spermiogenesis, dynein, myosin Va, MyRIP and Rab27b that compose microtubule-based and actin-based vesicle transport systems are actually present in the manchette and might possibly be involved in intramanchette transport.

  8. Rab27a (show RAB27A Proteins) and MyRIP regulate the amount and multimeric state of VWF (show VWF Proteins) released from endothelial cells.

  9. Slac2-c/MyRIP contains an N-terminal Slp (show SEPT9 Proteins) homology domain (SHD (show SHD Proteins)) and functions as a linker protein (show LAT Proteins) that interacts with myosin Rab27A/B (show RAB27A Proteins), VIIa/Va, and actin.

Mouse (Murine) Myosin VIIA and Rab Interacting Protein (MYRIP) interaction partners

  1. Exophilin8 transiently clusters insulin granules at the actin-rich cell cortex prior to exocytosis

  2. Slac2-c/MyRIP contains an N-terminal Slp (show SEPT9 Proteins) homology domain (SHD (show SHD Proteins)) and functions as a linker protein (show LAT Proteins) that interacts with myosin Rab27A/B (show RAB27A Proteins), VIIa/Va, and actin.

  3. Slac2-c acts as a functional myosin VIIa receptor and the Rab27A.Slac2-c x myosin VIIa tripartite protein complex regulates the transport of retinal melanosomes in pigment epithelium cells

  4. The present results provide evidence from live retinal pigment epithelium cells that the RAB27A-MYRIP-MYO7A complex functions in melanosome motility.

  5. Results suggest that the Rab27a-Myrip-MyoVIIa complex regulates tethering of melanosomes onto actin filaments, a process that ensures melanosome movement towards the cell periphery.

  6. indicate that MyRIP functions as a scaffolding protein that links protein kinase A to components of the exocytosis machinery

  7. Myrip is a versatile Rab27a-associated myosin-activating protein that mediates cellular activation of MyoVa and MyoVIIa via non-overlapping domains.

MYRIP Protein Profile

Protein Summary

Rab effector protein involved in melanosome transport. Serves as link between melanosome-bound RAB27A and the motor proteins MYO5A and MYO7A. May link RAB27A-containing vesicles to actin filaments. Functions as a protein kinase A-anchoring protein (AKAP). May act as a scaffolding protein that links PKA to components of the exocytosis machinery, thus facilitating exocytosis, including insulin release (By similarity).

Gene names and symbols associated with MYRIP

  • myosin VIIA and Rab interacting protein (MYRIP)
  • si:ch211-106h4.9 (si:ch211-106h4.9)
  • myosin VIIA and Rab interacting protein (myrip)
  • myosin VIIA and Rab interacting protein (LOC100156583)
  • myosin VIIA and Rab interacting protein (Myrip)
  • A230081N12Rik protein
  • LOC100156583 protein
  • MYRIP protein
  • si:dkey-189e1.4 protein
  • Slac2-c protein
  • Slac2c protein

Protein level used designations for MYRIP

myosin VIIA and Rab interacting protein , A kinase-anchoring protein , Ze-AKAP2 , rab effector MyRIP-like , Slp homologue lacking C2 domains , exophilin-8 , myosin-VIIa- and Rab-interacting protein , rab effector MyRIP , slp homolog lacking C2 domains c , synaptotagmin-like protein homologue lacking C2 domains-c , synaptotagmin-like protein lacking C2 domains C , exophilin 8 , slaC2-c

GENE ID SPECIES
428455 Gallus gallus
470796 Pan troglodytes
485603 Canis lupus familiaris
522113 Bos taurus
561671 Danio rerio
567049 Danio rerio
100068066 Equus caballus
100393249 Callithrix jacchus
100473210 Ailuropoda melanoleuca
100490150 Xenopus (Silurana) tropicalis
100543829 Meleagris gallopavo
100567669 Anolis carolinensis
100601114 Nomascus leucogenys
100156583 Sus scrofa
25924 Homo sapiens
245049 Mus musculus
360034 Rattus norvegicus
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