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MTMR7 encodes a member of the myotubularin family of tyrosine/dual-specificity phosphatases. Additionally we are shipping MTMR7 Antibodies (11) and many more products for this protein.
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The MTMR7 gene is linked to variant Creutzfeldt-Jakob risk in a genome-wide study.
MTMR7 forms a complex with MTMR9 (show MTMR9 Proteins) and dephosphorylates phosphatidylinositol 3-phosphate and Ins (show INS Proteins)(1,3)P2 in neuronal cells.
This gene encodes a member of the myotubularin family of tyrosine/dual-specificity phosphatases. The encoded protein is characterized by four distinct domains that are conserved among all members of the myotubularin family: the glucosyltransferase, Rab-like GTPase activator and myotubularins domain, the Rac-induced recruitment domain, the protein tyrosine phosphatases and dual-specificity phosphatases domain and the suppressor of variegation 3-9, enhancer-of-zeste, and trithorax interaction domain. This protein dephosphorylates the target substrates phosphatidylinositol 3-phosphate and inositol 1,3-bisphosphate. A pseudogene of this gene is found on chromosome 5.
myotubularin related protein 7
, myotubularin-related protein 7
, Myotubularin-related protein 7
, myotubularin-related protein 7-like