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N-Terminal EF-Hand Calcium Binding Protein 3 Proteins (NECAB3)

The protein encoded by NECAB3 interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. Additionally we are shipping NECAB3 Antibodies (25) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat NECAB3 NECAB3 311562  
NECAB3 63941 Q96P71
NECAB3 56846 Q9D6J4
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Top NECAB3 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,977.33
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

NECAB3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3) Interaction Partners

Human N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3) interaction partners

  1. hXB51 isoforms regulate Abeta (show APP Proteins) generation differently, either enhancing it by modifying the association of X11L (show APBA2 Proteins) with APP (show APP Proteins) or suppressing it in an X11L (show APBA2 Proteins)-independent manner

  2. xb51 may be required for maturation and maintenance of xb51-expressing neurons in the forebrain

Mouse (Murine) N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3) interaction partners

  1. The genes for the three Necab's, including Necab-3, were expressed in specific, non-overlapping areas of the hippocampus.

  2. Physical interactions of Nek2 (show NEK2 Proteins) with NIP1 (show DUOXA1 Proteins) were confirmed. In fact, Nek2 (show NEK2 Proteins) can phosphorylate NIP1 (show DUOXA1 Proteins) in vivo. Immunostaining experiments revealed that NIP1 (show DUOXA1 Proteins) is a Golgi protein (show GOLPH3 Proteins).

  3. xb51 may be required for maturation and maintenance of xb51-expressing neurons in the forebrain

NECAB3 Protein Profile

Protein Summary

The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with NECAB3

  • N-terminal EF-hand calcium binding protein 3 (Necab3)
  • N-terminal EF-hand calcium binding protein 3 (NECAB3)
  • N-terminal EF-hand calcium binding protein 3 (LOC100348638)
  • 2900010M17Rik protein
  • AI853434 protein
  • APBA2BP protein
  • dJ63M2.4 protein
  • dJ63M2.5 protein
  • EFCBP3 protein
  • NECAB3 protein
  • Nip1 protein
  • STIP3 protein
  • SYTIP2 protein
  • XB51 protein

Protein level used designations for NECAB3

amyloid beta (A4) precursor protein-binding, family A, member 1 binding protein , amyloid beta (A4) precursor protein-binding, family A, member 2 binding protein , N-terminal EF-hand calcium-binding protein 3 , N-terminal EF-hand calcium binding protein 3 , EF-hand calcium binding protein 3 , Nek2-interacting protein 1 , X11L-binding protein 51 , amyloid beta A4 protein-binding family A member 2-binding protein , neuronal calcium-binding protein 3 , neuronal calcium-binding protein NECAB3 , synaptotagmin interacting protein 2 , synaptotagmin interacting protein STIP3 , amyloid beta (A4) precursor protein-binding family A member 1 binding protein , mXB51

GENE ID SPECIES
311562 Rattus norvegicus
419154 Gallus gallus
458183 Pan troglodytes
608658 Canis lupus familiaris
100348638 Oryctolagus cuniculus
63941 Homo sapiens
56846 Mus musculus
514695 Bos taurus
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