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NADH Dehydrogenase (Ubiquinone) Fe-S Protein 1, 75kDa (NADH-Coenzyme Q Reductase) (NDUFS1) ELISA Kits

The protein encoded by NDUFS1 belongs to the complex I 75 kDa subunit family. Additionally we are shipping NDUFS1 Antibodies (71) and NDUFS1 Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse NDUFS1 NDUFS1 227197 Q91VD9
Anti-Rat NDUFS1 NDUFS1 301458 Q66HF1
NDUFS1 4719 P28331
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Top NDUFS1 ELISA Kits at antibodies-online.com

Showing 1 out of 2 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.115 ng/mL 0.31-20 ng/mL 96 Tests Log in to see 9 to 11 Days
$736.84
Details

More ELISA Kits for NDUFS1 Interaction Partners

Mouse (Murine) NADH Dehydrogenase (Ubiquinone) Fe-S Protein 1, 75kDa (NADH-Coenzyme Q Reductase) (NDUFS1) interaction partners

  1. lysosomal membrane permeability induced by TNFalpha (show TNF ELISA Kits) plus cycloheximide, the release of lysosomal cathepsins and reactive oxygen species formation require the caspase-3 (show CASP3 ELISA Kits)-mediated cleavage of the p75 (show NGFR ELISA Kits) NDUFS1 subunit of respiratory complex I.

Human NADH Dehydrogenase (Ubiquinone) Fe-S Protein 1, 75kDa (NADH-Coenzyme Q Reductase) (NDUFS1) interaction partners

  1. Results found nominal significant associations of 2 SNPs in the NDUFS1 gene and 4 SNPs in the NDUFS2 (show NDUFS2 ELISA Kits) gene with early onset schizophrenia (EOS (show IKZF4 ELISA Kits)), but none of these associations survived the Bonferroni correction.

  2. Loss of FOXRED1 (show FOXRED1 ELISA Kits), coupled with protein, choline and/or folate-deficient diets results in the depletion of glutathione, the dysregulation of nitric oxide metabolism and the peroxynitrite-mediated inactivation of complex I.

  3. NDUFS1 may confer susceptibility to schizophrenia in male subjects, acting as a causative factor for the severity of negative symptoms in schizophrenia.

  4. The presented clinical courses of NDUFV1 (show NDUFV1 ELISA Kits) and NDUFS1 mutation-based complex I deficiencies are characterized by leukoencephalopathy or early death and expand the already heterogeneous phenotypic spectrum.

  5. Some mutations in NDUFS1 cause a milder phenotype with a more benign course despite the initial decompensation phase. Homozygosity for the c.755A > G missense mutation may correlate with the milder clinical picture in the patient.

  6. homozygous c.1783A>G (p.Thr595Ala) mutation in NDUFS1 in two inbred siblings with isolated complex I deficiency associated to a progressive cavitating leukoencephalopathy

  7. report 3 patients with low residual complex I activity who displayed novel mutations in the NDUFS1 gene. One mutation introduces a premature stop codon, 3 mutations cause a substitution of amino acids and another mutation a deletion of one amino acid.

  8. A patient with Leigh syndrome had a mutation in the NDUFS1 protein of Complex I of the Respiratory Chain. Identifying nuclear mutations will help us understand how molecular defects can lead to complex I deficiency.

  9. mutations in the NDUFS1 and NDUFS4 (show NDUFS4 ELISA Kits) genes of complex I cause dysfunction in cellular oxidative metabolism

Cow (Bovine) NADH Dehydrogenase (Ubiquinone) Fe-S Protein 1, 75kDa (NADH-Coenzyme Q Reductase) (NDUFS1) interaction partners

  1. Data show that during NADH-ubiquinone oxidoreductase (Complex (show NDUFA2 ELISA Kits) I) catalytic electron transfer from NADH to DBQ, the superoxide generation site was mostly shifted to the SQ.

  2. Data suggest that Q(Nf) plays a role in a "direct" redox-driven proton pump, while Q(Ns) triggers an "indirect" conformation-driven proton pump in NADH-ubiquinone oxidoreductase (complex (show NDUFA2 ELISA Kits) I).

  3. Bovine heart NADH-ubiquinone oxidoreductase contains one molecule of ubiquinone with ten isoprene units as one of the cofactors

NDUFS1 Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This protein is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. Mutations in this gene are associated with complex I deficiency. Several transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with NDUFS1

  • NADH dehydrogenase (ubiquinone) Fe-S protein 1 (Ndufs1) antibody
  • NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) (NDUFS1) antibody
  • 5830412M15Rik antibody
  • 9930026A05Rik antibody
  • CI-75k antibody
  • CI-75Kd antibody
  • PRO1304 antibody

Protein level used designations for NDUFS1

CI-75kD , NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial , complex I-75kD , NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa , complex I 75kDa subunit , complex I, mitochondrial respiratory chain, 75-kD subunit , mitochondrial NADH-ubiquinone oxidoreductase 75 kDa subunit

GENE ID SPECIES
227197 Mus musculus
301458 Rattus norvegicus
4719 Homo sapiens
478880 Canis lupus familiaris
288380 Bos taurus
100516402 Sus scrofa
459896 Pan troglodytes
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