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NADPH Oxidase Activator 1 Proteins (NOXA1)

NOXA1 encodes a protein which activates NADPH oxidases, enzymes which catalyze a reaction generating reactive oxygen species. Additionally we are shipping NOXA1 Antibodies (32) and NOXA1 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NOXA1 10811 Q86UR1
NOXA1 241275 Q8CJ00
NOXA1 311793 A7E3N7
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Top NOXA1 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,250.50
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 19 Days
$785.40
Details

NOXA1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for NADPH Oxidase Activator 1 (NOXA1) Interaction Partners

Human NADPH Oxidase Activator 1 (NOXA1) interaction partners

  1. A NOXA1 peptide blocked NOXA1-Nox1 (show NOX1 Proteins) binding. The finding identifies a NOXA1-activating domain and an isoform-specific Nox1 (show NOX1 Proteins) inhibitor.

  2. Phosphorylation of Thr341 allows Noxo1 (show NOXO1 Proteins) to sufficiently interact with Noxa1, an interaction that participates in Nox1 (show NOX1 Proteins) activation

  3. Noxa1 has quite different kinetic properties from p67(phox (show NCF2 Proteins)) and suggest that Noxa1 may function as a moderate activator of Nox2 (show CYBB Proteins).

  4. Tks4 (show SH3PXD2B Proteins) and Tks5 directly bind to NoxA1. The integrity of the N-terminal PRR (show PVRL1 Proteins) of NoxA1 is essential for this direct interaction with the Tks (show PTK6 Proteins) proteins.

  5. The Nox1 (show NOX1 Proteins)-dependent generation of reactive oxygen species is dependent on Src (show SRC Proteins) phosphorylation of NoxA1 and Tks4 (show SH3PXD2B Proteins). Blockage of phosphorylation of NoxA1 and Tks4 (show SH3PXD2B Proteins) decreases Nox1 (show NOX1 Proteins)-dependent ROS (show ROS1 Proteins) generation and blocks SrcYF-induced invadopodia formation.

  6. The first quantitative characterization of the interactions made between the cytosolic regulators NOXO1 (show NOXO1 Proteins) and NOXA1 and membrane-bound p22(phox (show CYBA Proteins)), is presented.

  7. these results demonstrate that phosphorylation of NoxA1 is a part of the feedback mechanism that functions through activation of Rac (show AKT1 Proteins) with a net outcome of negative modulation of Nox1 (show NOX1 Proteins) activity.

  8. NoxA1 is the functional homolog of p67phox (show NCF2 Proteins) in vascular smooth muscle cells (VSMC) that regulates redox signaling and VSMC phenotype.

  9. These studies demonstrate that, in reconstituted NOX1/NOXO1/NOXA1 systems, the NOXA1 SH3 domain is not required for function but, when present, can critically modulate the activity of the enzyme system.

  10. PKA-phosphorylated NoxA1 is a new binding partner of 14-3-3 protein (show YWHAE Proteins); this forms the basis of a novel mechanism regulating the formation of ROS (show ROS1 Proteins) by Nox1 (show NOX1 Proteins) and, potentially, other NoxA1-regulated Nox family members

Mouse (Murine) NADPH Oxidase Activator 1 (NOXA1) interaction partners

  1. The first quantitative characterization of the interactions made between the cytosolic regulators NOXO1 (show NOXO1 Proteins) and NOXA1 and membrane-bound p22(phox (show CYBA Proteins)), is presented.

  2. NoxA1 is the functional homolog of p67phox (show NCF2 Proteins) in vascular smooth muscle cells (VSMC) that regulates redox signaling and VSMC phenotype.

  3. role in activating superoxide generation by the NADPH oxidase (show NOX1 Proteins) NOX1 (show NOX1 Proteins)

NOXA1 Protein Profile

Protein Summary

This gene encodes a protein which activates NADPH oxidases, enzymes which catalyze a reaction generating reactive oxygen species. The encoded protein contains four N-terminal tetratricopeptide domains and a C-terminal Src homology 3 domain. Interaction between the encoded protein and proteins in the oxidase regulatory complex occur via the tetratricopeptide domains. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with NOXA1

  • NADPH oxidase activator 1 (NOXA1)
  • NADPH oxidase activator 1 (Noxa1)
  • NY-CO-31 protein
  • p51NOX protein
  • SDCCAG31 protein

Protein level used designations for NOXA1

NCF2-like protein , Nox activator 1 , antigen NY-CO-31 , inhibitory NADPH oxidase activator 1 , p51-nox , p67phox-like factor , serologically defined colon cancer antigen 31 , predicted NADPH oxidase activator 1

GENE ID SPECIES
10811 Homo sapiens
241275 Mus musculus
311793 Rattus norvegicus
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