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NADPH oxidases (NOXs) catalyze the transfer of electrons from NADPH to molecular oxygen to generate reactive oxygen species (ROS). Additionally we are shipping NADPH Oxidase Organizer 1 Proteins (5) and NADPH Oxidase Organizer 1 Kits (2) and many more products for this protein.
Showing 10 out of 63 products:
Human Polyclonal NOXO1 Primary Antibody for IHC (p), IHC - ABIN268754
Chung, Kim, Kim, Yim, Chock et al.: Dual function of protein kinase C (PKC) in 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced manganese superoxide dismutase (MnSOD) expression: activation of CREB and FOXO3a by PKC-alpha ... in The Journal of biological chemistry 2011
Show all 3 Pubmed References
Human Polyclonal NOXO1 Primary Antibody for IHC, ELISA - ABIN185195
Bánfi, Clark, Steger, Krause: Two novel proteins activate superoxide generation by the NADPH oxidase NOX1. in The Journal of biological chemistry 2003
Show all 2 Pubmed References
Differential Roles of Protein Complexes NOX1 (show NOX1 PLURAL_@4318@)-NOXO1 and NOX2 (show CYBB PLURAL_@4318@)-p47phox (show NCF1 PLURAL_@4318@) in Mediating Endothelial Redox Responses to Oscillatory and Unidirectional Laminar Shear Stress.
Data from pull-down assay between the Noxo1 and Noxa1 (show NOXA1 Antibodies) showed that the SH3 domains (Noxa1 (show NOXA1 Antibodies)) is responsible for interaction with Noxo1 C-terminal tail harboring proline rich region.
TNF-alpha (show TNF Antibodies)/TNFR1 (show TNFRSF1A Antibodies) signaling promotes gastric tumorigenesis through induction of Noxo1 and Gna14 (show GNa14 Antibodies) in tumor cells.
Phosphorylation of Thr341 allows Noxo1 to sufficiently interact with Noxa1 (show NOXA1 Antibodies), an interaction that participates in Nox1 (show NOX1 Antibodies) activation
Phorbol myristate acetate stimulates NOXO1 phosphorylation in a transfected human embryonic kidney (HEK (show EPHA3 Antibodies)) 293 epithelial cell model via protein kinase C (show PKC Antibodies) and identify Ser (show SIGLEC1 Antibodies)-154 as the major phosphorylated site.
The first quantitative characterization of the interactions made between the cytosolic regulators NOXO1 and NOXA1 (show NOXA1 Antibodies) and membrane-bound p22(phox (show CYBA Antibodies)), is presented.
NOXO1 and NOXA1 (show NOXA1 Antibodies) activate Nox1 (show NOX1 Antibodies) without the need for agonist activation, and this is mediated in part by binding of the NOXO1 PX domain to membrane lipids.
NOXO1, p47phox (show NCF1 Antibodies), and p67phox (show NCF2 Antibodies) regulate Nox3 (show NOX3 Antibodies)
These results suggest that the formation of the complex consisting of Nox1 (show NOX1 Antibodies), betaPix (show ARHGEF7 Antibodies), and NoxO1 is likely to be a critical step in EGF (show EGF Antibodies)-induced ROS (show ROS1 Antibodies) generation.
This study shows the expression of alternatively spliced transcripts of the NOXO1 gene and the roles of the protein products in the activation of Nox oxidases.
These findings suggest that Nox activation involves a conformational change leading to disruption of the bis (show BAG3 Antibodies)-SH3-PRR (show PVRL1 Antibodies) interaction in Noxo1.
NoxO1 stimulates alpha-secretase activity probably through reactive oxygen species-mediated oxidation. Deletion of NoxO1 attenuates Notch (show NOTCH1 Antibodies) signaling and thereby promotes a tip-cell phenotype that results in increased angiogenesis.
Genetic susceptibility to alcoholic steatohepatitis was linked to two candidate genes, Noxo1 (and Nlrc4 (show NLRC4 Antibodies)).
role in activating superoxide generation by the NADPH oxidase (show NOX1 Antibodies) NOX1 (show NOX1 Antibodies)
This gene encodes an NADPH oxidase (NOX) organizer, which positively regulates NOX1 and NOX3. The protein contains a PX domain and two SH3 domains. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
NADPH oxidase organizer 1
, NADPH oxidase organizer 1-like
, NADPH oxidase regulatory protein
, Nox organizer 1
, SH3 and PX domain-containing protein 5
, nox-organizing protein 1
, regulatory protein P41NOX
, nox organizer 1
, sorting nexin-28