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anti-NDC80 Kinetochore Complex Component Homolog (S. Cerevisiae) (NDC80) Antibodies

NDC80 encodes a component of the NDC80 kinetochore complex. Additionally we are shipping NDC80 Kinetochore Complex Component Homolog (S. Cerevisiae) Proteins (5) and NDC80 Kinetochore Complex Component Homolog (S. Cerevisiae) Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NDC80 67052 Q9D0F1
NDC80 10403 O14777
NDC80    
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Top anti-NDC80 Kinetochore Complex Component Homolog (S. Cerevisiae) Antibodies at antibodies-online.com

Showing 10 out of 77 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Mouse Un-conjugated WB KNTC2 monoclonal antibody (M01), clone 1A10 Western Blot analysis of K... 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Dog Mouse Un-conjugated IF, WB Western blot analysis of HEC on a Jurkat lysate. Lane 1: 1:250, lane 2... Immunoflourescence staining of BC3H1, a murine skeletal muscle cell li... 50 μg Log in to see 5 to 6 Days
$205.42
Details
Human Goat Un-conjugated ELISA, WB ABIN184821 staining (0.5µg/ml) of Hela lysate (RIPA buffer, 35µg total... 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Mouse Un-conjugated IF, WB Western blot analysis of HEC on a Jurkat lysate. Lane 1: 1:250, lane 2... Immunoflourescence staining of BC3H1, a murine skeletal muscle cell li... 150 μg Log in to see 5 to 6 Days
$398.54
Details
Human Rabbit Un-conjugated IF, ELISA, WB Western blot analysis of extracts from Jurkat cells, using KNTC2 Antib... Immunofluorescence analysis of HuvEc cells, using KNTC2 Antibody. The ... 100 μg Log in to see 2 to 3 Days
$275.00
Details
Human Mouse Un-conjugated ELISA, WB KNTC2 monoclonal antibody (M01), clone 1A10 Western Blot analysis of K... Detection limit for recombinant GST tagged KNTC2 is approximately 0.1n... 100 μg Log in to see 9 Days
$430.00
Details
Human Goat Un-conjugated EIA, IHC (p), WB Human Adrenal (formalin-fixed, paraffin-embedded) stained with NDC80at... Human Liver (formalin-fixed, paraffin-embedded) stained with NDC80at 5... 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Goat Un-conjugated IHC (p), ELISA, WB Human Liver (formalin-fixed, paraffin-embedded) stained with NDC80 ant... Human Adrenal (formalin-fixed, paraffin-embedded) stained with NDC80 a... 50 μg Log in to see 8 to 10 Days
$451.00
Details

NDC80 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine) , , , ,

Human , , , ,
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Rat (Rattus) , , , ,

Top referenced anti-NDC80 Kinetochore Complex Component Homolog (S. Cerevisiae) Antibodies

  1. Human Monoclonal NDC80 Primary Antibody for WB - ABIN394739 : Olson, Wang, Pankratz, Fredericksen, Vachon, Vierkant, Cerhan, Couch: Centrosome-related genes, genetic variation, and risk of breast cancer. in Breast cancer research and treatment 2010 (PubMed)
    Show all 5 references for ABIN394739

  2. Human Monoclonal NDC80 Primary Antibody for ELISA, WB - ABIN564521 : Scott, Nogueira, Heffernan, van Doorn, Dhakal, Hanna, Min, Jaskelioff, Xiao, Wu, Cameron, Perry, Zeid, Feinberg, Kim, Vande Woude, Granter, Bosenberg, Chu, DePinho, Rimm, Chin: Proinvasion metastasis drivers in early-stage melanoma are oncogenes. in Cancer cell 2011 (PubMed)

  3. Human Polyclonal NDC80 Primary Antibody for WB - ABIN374264 : Chen, Riley, Chen, Lee: HEC, a novel nuclear protein rich in leucine heptad repeats specifically involved in mitosis. in Molecular and cellular biology 1997 (PubMed)

More Antibodies against NDC80 Kinetochore Complex Component Homolog (S. Cerevisiae) Interaction Partners

Fruit Fly (Drosophila melanogaster) NDC80 Kinetochore Complex Component Homolog (S. Cerevisiae) (NDC80) interaction partners

  1. kinetochores movement depends on SPC105R, can occur in the absence of NDC80, and is antagonized by plus-end directed forces from the CENP-E (show CENPE Antibodies) motor.

Mouse (Murine) NDC80 Kinetochore Complex Component Homolog (S. Cerevisiae) (NDC80) interaction partners

  1. Hec1-dependent cyclin B2 (show CCNB2 Antibodies) stabilization during early metaphase is important for early-stage spindle assembly.

  2. Disruption of Ndc80 function by either siRNA injection or antibody injection resulted in severe chromosome misalignment, spindle disruption, and precocious polar body extrusion.

  3. overexpression of Hec1 results in mitotic checkpoint (show BUB3 Antibodies) hyperactivation that leads to aneuploidy sufficient to generate tumors

Human NDC80 Kinetochore Complex Component Homolog (S. Cerevisiae) (NDC80) interaction partners

  1. Independent molecular binding events to microtubules (MTs (show TIMM8A Antibodies)) by individual NDC80 complexes, rather than their structured oligomers, regulate the dynamics and stability of kinetochore-MT attachments in dividing cells.

  2. The Ndc80 complex binds straight microtubules by recognizing the dimeric interface of tubulin (show TUBB Antibodies).

  3. Overproduction of Ndc80 in cancer cells may unfavourably absorb protein interactors through the internal loop domain and lead to a change in the equilibrium of microtubule-associated proteins. [Review]

  4. N-terminus-modified Hec1 suppresses tumour growth by interfering with kinetochore-microtubule dynamics

  5. Mechanisms of mitosis-specific assembly of the checkpoint platform Knl1 (show CASC5 Antibodies)/MIS12 (show MIS12 Antibodies)/NDC80 at human kinetochores.

  6. Certain clinical subtypes of breast cancer more likely to respond to Hec1-targeted therapy were identified and these subtypes are the ones associated with poor prognosis.

  7. Hec1 is critical in maintaining the in vitro and in vivo growth of gastric cancer cells; elevated Hec1 levels may occur at the early stage of gastric tumorigenesis

  8. Growth inhibition following knockdown of NDC80, CDK1 (show CDK1 Antibodies) and PLK1 (show PLK1 Antibodies).

  9. Hec1 expression was highest in paclitaxel-resistant A2780/Taxol cells.

  10. these findings demonstrated that three buried glutamic acid-lysine pairs, in concert with hydrophobic interactions of core residues, provide the major specificity and stability requirements for Hec1-Nuf2 dimerization

Xenopus laevis NDC80 Kinetochore Complex Component Homolog (S. Cerevisiae) (NDC80) interaction partners

  1. mature attachment via the Ndc80 complex is essential for metaphase alignment and anaphase A

NDC80 Kinetochore Complex Component Homolog (S. Cerevisiae) (NDC80) Antigen Profile

Protein Summary

This gene encodes a component of the NDC80 kinetochore complex. The encoded protein consists of an N-terminal microtubule binding domain and a C-terminal coiled-coiled domain that interacts with other components of the complex. This protein functions to organize and stabilize microtubule-kinetochore interactions and is required for proper chromosome segregation.

Gene names and symbols associated with NDC80

  • NDC80 kinetochore complex component (NDC80) antibody
  • CG9938 gene product from transcript CG9938-RA (Ndc80) antibody
  • NDC80 homolog, kinetochore complex component (S. cerevisiae) (NDC80) antibody
  • NDC80 kinetochore complex component homolog (S. cerevisiae) (NDC80) antibody
  • spindle pole body protein Ndc80 (ndc80) antibody
  • kinetochore protein Ndc80 (ndc80) antibody
  • Kinetochore protein NDC80 homolog (ndc80) antibody
  • NDC80 homolog, kinetochore complex component (S. cerevisiae) (Ndc80) antibody
  • NDC80 homolog, kinetochore complex component (S. cerevisiae) (ndc80) antibody
  • NDC80 kinetochore complex component (ndc80) antibody
  • 2610020P18Rik antibody
  • AV139730 antibody
  • CG9938 antibody
  • Dmel\\CG9938 antibody
  • dmNdc80 antibody
  • dNdc80 antibody
  • HEC antibody
  • HEC1 antibody
  • HsHec1 antibody
  • hsNDC80 antibody
  • kntc2 antibody
  • kntc2l antibody
  • ndc10 antibody
  • NDC80 antibody
  • TID3 antibody
  • wu:fb52e02 antibody
  • zgc:111801 antibody

Protein level used designations for NDC80

kinetochore associated 2 , CG9938-PA , Hec1 , Ndc80-PA , NDC80 homolog, kinetochore complex component (S. cerevisiae) , NDC80 homolog, kinetochore complex component , kinetochore protein NDC80 homolog , kinetochore protein Ndc80 , Kinetochore protein NDC80 homolog , highly expressed in cancer, rich in leucine heptad repeats , kinetochore protein Hec1 , kinetochore-associated protein 2 , HEC (highly expressed in cancer) , NDC80 kinetochore complex component homolog , highly expressed in cancer protein , retinoblastoma-associated protein HEC , kinetochore spindle checkpoint protein Ndc80 , xNdc80

GENE ID SPECIES
100226934 Taeniopygia guttata
32316 Drosophila melanogaster
455320 Pan troglodytes
480190 Canis lupus familiaris
538789 Bos taurus
2540097 Schizosaccharomyces pombe 972h-
8624354 Dictyostelium discoideum AX4
100051228 Equus caballus
100073682 Ornithorhynchus anatinus
100380518 Salmo salar
100454766 Pongo abelii
100465936 Ailuropoda melanoleuca
100583588 Nomascus leucogenys
67052 Mus musculus
445386 Danio rerio
10403 Homo sapiens
398429 Xenopus laevis
395134 Gallus gallus
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