anti-NEK7 (NEK7) Antibodies

NIMA-related kinases share high amino acid sequence identity with the gene product of the Aspergillus nidulans 'never in mitosis A' gene, which controls initiation of mitosis.[supplied by OMIM, Jul 2002].. Additionally we are shipping NEK7 Proteins (15) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NEK7 59125 Q9ES74
NEK7 140609 Q8TDX7
NEK7 360850 D3ZBE5
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Top anti-NEK7 Antibodies at antibodies-online.com

Showing 10 out of 106 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-NEK7 Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-Nek7 Antibody Titration: 1.0 ug/ml Positive Control: Rat Liver 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Goat Un-conjugated EIA, WB AP22436PU-N NEK7 antibody staining of HeLa lysate at 0.05 µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of NEK7 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the an Western blot analysis of NEK7 expression in HepG2 (A), Jurkat (B), mouse heart (C) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Goat Un-conjugated ELISA, WB Western Blot: NEK7 Antibody [NBP1-68866] - Analysis of Mouse Lung (A), Mouse Testis (B), Rat Lung (C) and Rat Testis (D) lysates (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Western Blot: NEK7 Antibody [NBP1-68866] - NBP1-68866 (0.1ug/ml) staining of Human Lung lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 7 to 9 Days
$485.88
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from HepG2/Jurkat/COLO cells, using NEK7 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using NEK7 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$481.25
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using NEK7, antibody at 1:200 dilution. WB Image Sample(30 μg of whole cell lysate) A:HeLa S3, 12% SDS PAGE antibody diluted at 1:500 100 μL Log in to see 1 to 2 Days
$358.60
Details
Bat Goat Un-conjugated IHC (p), ELISA, WB 50 μg Log in to see 7 to 9 Days
$451.00
Details

NEK7 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-NEK7 Antibodies

  1. Human Polyclonal NEK7 Primary Antibody for ELISA, WB - ABIN4234492 : Olson, Wang, Pankratz, Fredericksen, Vachon, Vierkant, Cerhan, Couch: Centrosome-related genes, genetic variation, and risk of breast cancer. in Breast cancer research and treatment 2010 (PubMed)

More Antibodies against NEK7 Interaction Partners

Mouse (Murine) NEK7 interaction partners

  1. NEK7 serves as a cellular switch that enforces mutual exclusivity of the inflammasome response and cell division.

  2. murine macrophages deficient in Nek7 displayed a largely blunted Nlrp3 (show NLRP3 Antibodies) inflammasome response.

  3. NEK7 is an essential protein that acts downstream of potassium efflux to mediate NLRP3 (show NLRP3 Antibodies) inflammasome assembly and activation

  4. results confirm Nek7 as a regulator of cell division, and reveal it as an essential component for mammalian growth and survival

  5. During early embryogenesis nek7 is expressed in the site of decidual reaction. Later in embryogenesis, nek7 is highly expressed in the dorsal thalamus.

Human NEK7 interaction partners

  1. Results demonstrate that NEK7 is involved in the timely regulation of G1 progression, S-phase entry, and procentriole formation.

  2. Signaling cascade of the NIMA-related kinases (Neks) Nek6 (show NEK6 Antibodies), Nek7, and Nek9 (show NEK9 Antibodies) is required for the localization and function of two kinesins essential for cytokinesis, Mklp2 (show KIF20A Antibodies) and Kif14 (show KIF14 Antibodies) to properly coordinate cytokinesis.

  3. TRF1 (show TERF1 Antibodies) phosphorylation by Nek7 favors the binding of shelterin protein TIN2 (show TINF2 Antibodies) and disfavors E3 ligase Fbx4 (show FBXO4 Antibodies) interaction, thus preventing TRF1 (show TERF1 Antibodies) ubiquitination and proteasome degradation to maintain telomere integrity.

  4. Studies indicate that NIMA related kinase 7 (NEK7) targets at NLRP3 (show NLRP3 Antibodies) protein and involves in the activation of NLRP3 (show NLRP3 Antibodies) inflammasome.

  5. Study highlights for the first time the possible role of Nek7 in HCC (show FAM126A Antibodies) progression. Nek7 would be a useful biomarker that early predicts HCC (show FAM126A Antibodies) patients at higher risk of poor prognosis.

  6. NEK7 serves as a cellular switch that enforces mutual exclusivity of the inflammasome response and cell division.

  7. The C-terminal domain of Nek9 (show NEK9 Antibodies) activates Nek7 through promoting back-to-back dimerization.

  8. Results show that NEK7 was directly regulated by WHSC1 (show WHSC1 Antibodies) through H3K36me2 and its knockdown significantly reduced cell-cycle progression, indicating that NEK7 is a key player in the molecular pathway regulated by WHSC1 (show WHSC1 Antibodies).

  9. RGS2 (show RGS2 Antibodies) or Nek7 depletion or even overexpression of wild-type or kinase-dead Nek7, reduced gamma-tubulin (show TUBG1 Antibodies) from the mitotic spindle poles.

  10. Nek7 increased Ser (show SIGLEC1 Antibodies)/Thr (show TRH Antibodies) phosphorylation of Anks3 primarily within ankyrin domain.Interaction with Anks3 led to cytoplasmic retention and nuclear exclusion of Nek7.

NEK7 Antigen Profile

Protein Summary

NIMA-related kinases share high amino acid sequence identity with the gene product of the Aspergillus nidulans 'never in mitosis A' gene, which controls initiation of mitosis.

Gene names and symbols associated with anti-NEK7 (NEK7) Antibodies

  • NIMA (never in mitosis gene a)-related expressed kinase 7 (Nek7) antibody
  • NIMA-related kinase 7 (nek7) antibody
  • NIMA related kinase 7 (NEK7) antibody
  • NIMA-related kinase 7 S homeolog (nek7.S) antibody
  • NIMA-related kinase 7 (Nek7) antibody
  • 2810460C19Rik antibody
  • AtNek7 antibody
  • AU020186 antibody
  • NIMA-related kinase 7 antibody
  • wu:fj68f02 antibody
  • zgc:92175 antibody
  • zgc:100962 antibody

Protein level used designations for anti-NEK7 (NEK7) Antibodies

NIMA-related expressed kinase 7 , NIMA-related kinase 7 , never in mitosis A-related kinase 7 , nimA-related protein kinase 7 , serine/threonine-protein kinase Nek7 , NIMA (never in mitosis gene a)-related kinase 7 , NIMA-family kinase Nek7 , NIMA (never in mitosis gene a)-related expressed kinase 7

GENE ID SPECIES
59125 Mus musculus
445223 Danio rerio
424350 Gallus gallus
480008 Canis lupus familiaris
100521742 Sus scrofa
140609 Homo sapiens
414882 Xenopus laevis
781355 Bos taurus
360850 Rattus norvegicus
820397 Arabidopsis thaliana
Selected quality suppliers for anti-NEK7 (NEK7) Antibodies
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