anti-NFU1 Iron-Sulfur Cluster Scaffold Homolog (S. Cerevisiae) (NFU1) Antibodies

NFU1 encodes a protein that is localized to mitochondria and plays a critical role in iron-sulfur cluster biogenesis. Additionally we are shipping NFU1 Iron-Sulfur Cluster Scaffold Homolog (S. Cerevisiae) Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NFU1 27247 Q9UMS0
NFU1 56748 Q9QZ23
NFU1    
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Top anti-NFU1 Iron-Sulfur Cluster Scaffold Homolog (S. Cerevisiae) Antibodies at antibodies-online.com

Showing 2 out of 5 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of various cell lines, using NFU1 antibody. Immunohistochemistry of paraffin-embedded rat lung using NFU1 antibody at dilution of 1:200 (40x lens). 100 μL Log in to see 16 Days
$334.02
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p) Immunohistochemistry-Paraffin: NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae) Antibody [NBP2-48647] - Staining of human vulva/anal skin shows strong cytoplasmic positivity in epidermal cells. Immunocytochemistry/Immunofluorescence: NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae) Antibody [NBP2-48647] - Analysis of human cell line U-2 OS shows positivity in cytoplasm & nucleus but excluded from the nucleoli. 0.1 mL Log in to see 10 to 13 Days
$491.63
Details

NFU1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human ,


Mouse (Murine)


Rat (Rattus)


More Antibodies against NFU1 Iron-Sulfur Cluster Scaffold Homolog (S. Cerevisiae) Interaction Partners

Human NFU1 Iron-Sulfur Cluster Scaffold Homolog (S. Cerevisiae) (NFU1) interaction partners

  1. report the results of an investigation on the effect of these substitutions on both cluster coordination and NFU1 structure and function

  2. Gly189Arg substitution on NFU1 is associated with multiple mitochondrial dysfunctions syndrome 1.

  3. a direct role for human Nfu in the process of [2Fe-2S] cluster trafficking and delivery

  4. Analysis of protein stability and oligomeric state demonstrates that the Gly208Cys mutant increases the propensity to dimerize and perturbs the secondary structure composition. These changes appear to underlie the severely decreased ability of mutant NFU1 to accept an Fe/S cluster from physiologically relevant sources.

  5. Study used NMR spectroscopy and small-angle X-ray scattering data to determine the 3D structure of human mitochondrial NFU1 in its apo (show C9orf3 Antibodies)- and iron-sulfur cluster-containing holo-form. Apo (show C9orf3 Antibodies)- NFU1 is monomeric, whereas holo-NFU1 consists of a trimer of three [4Fe-4S] cluster-linked dimers.

  6. a leaky splicing regulation due to a splice site mutation (c.545+5G>A) that produces small amounts of wild type NFU1 mRNA that might result in enough protein to partially lipoylate and restore the activity of lipoic acid-dependent enzymes and the assembly and activity of complex I.

  7. A new NFU1 mutation is reported in a patient presenting with a milder phenotype characterized by a later onset, a slowly progressive spastic paraparesis with relapsing-remitting episodes, mild cognitive impairment and a long survival.

  8. This study provides new insights into the molecular bases of NFU1 disease.

  9. A fatal mitochondrial disease is associated with defective NFU1 function in the maturation of a subset of mitochondrial Fe-S proteins

  10. Mutations in iron-sulfur cluster scaffold genes NFU1 and BOLA3 (show BOLA3 Antibodies) cause a fatal deficiency of multiple respiratory chain and 2-oxoacid dehydrogenase enzymes [case report]

NFU1 Iron-Sulfur Cluster Scaffold Homolog (S. Cerevisiae) (NFU1) Antigen Profile

Protein Summary

This gene encodes a protein that is localized to mitochondria and plays a critical role in iron-sulfur cluster biogenesis. The encoded protein assembles and transfers 4Fe-4S clusters to target apoproteins including succinate dehydrogenase and lipoic acid synthase. Mutations in this gene are a cause of multiple mitochondrial dysfunctions syndrome-1, and pseudogenes of this gene are located on the short arms of chromosomes 1 and 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with NFU1

  • NFU1 iron-sulfur cluster scaffold (NFU1) antibody
  • NFU1 iron-sulfur cluster scaffold (Nfu1) antibody
  • 0610006G17Rik antibody
  • CGI-33 antibody
  • HIRIP antibody
  • Hirip5 antibody
  • MMDS1 antibody
  • Nfu antibody
  • NifU antibody
  • NIFUC antibody

Protein level used designations for NFU1

HIRA-interacting protein 5 , NFU1 iron-sulfur cluster scaffold homolog, mitochondrial , NifU-like C-terminal domain containing , iron-sulfur cluster scaffold protein , histone cell cycle regulation defective interacting protein 5 , mHIRIP5

GENE ID SPECIES
27247 Homo sapiens
56748 Mus musculus
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