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NIMA (Never in Mitosis Gene A)-Related Kinase 2 (NEK2) ELISA Kits

NEK2 encodes a serine/threonine-protein kinase that is involved in mitotic regulation. Additionally we are shipping NEK2 Antibodies (136) and NEK2 Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse NEK2 NEK2 18005 O35942
Anti-Rat NEK2 NEK2 114482  
Anti-Human NEK2 NEK2 4751 P51955
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More ELISA Kits for NEK2 Interaction Partners

Mouse (Murine) NIMA (Never in Mitosis Gene A)-Related Kinase 2 (NEK2) interaction partners

  1. Cep85 is a bona fide Nek2A-binding partner that surrounds the proximal ends of centrioles where it cooperates with PP1gamma (also known as PPP1CC (show PPP1CC ELISA Kits)) to antagonize Nek2A

  2. The results suggest that overexpression of NEK2 has the potential to serve as a biomarker for PCa (show ENPP1 ELISA Kits) prognosis.

  3. Nek2 transgenic mice develop spontaneous germinal centers and exhibit an enhanced T cell dependent immune response our data demonstrates a novel role for Nek2 in regulating B cell development and the immune response

  4. these data indicate that Nek2 has a pivotal role in breast cancer growth at primary and secondary sites, and thus may be an attractive and novel therapeutic target for this disease.

  5. CIP2A strongly interacts with NEK2 during G2/M phase, thereby enhancing NEK2 kinase activity to facilitate centrosome separation in a PP1- and PP2A-independent manner.

  6. Nek2 and its substrate, centrobin/Nip2, are required for proper meiotic spindle formation of the mouse oocytes

  7. Data show that NEK2 was identified as a tumor-associated antigen.

  8. Nek2 may be a mitotic regulator that is involved in diverse cell cycle events.

  9. Tcp10 promoter-directed expression of the Nek2 gene in mouse meiotic spermatocytes.

  10. The MAPK (show MAPK1 ELISA Kits) pathway triggers activation of Nek2 during chromosome condensation in mouse spermatocytes.

Human NIMA (Never in Mitosis Gene A)-Related Kinase 2 (NEK2) interaction partners

  1. Hepatocellular carcinoma patients with high NEK2 expression had significantly poor recurrence-free survival (p=0.042) and early recurrence after hepatectomy.

  2. Cep85 is a bona fide Nek2A-binding partner that surrounds the proximal ends of centrioles where it cooperates with PP1gamma (also known as PPP1CC (show PPP1CC ELISA Kits)) to antagonize Nek2A

  3. Kif24 (show KIF24 ELISA Kits) is a physiological substrate of Nek2, which regulates cilia disassembly through a concerted mechanism involving Kif24 (show KIF24 ELISA Kits)-mediated microtubule depolymerization.

  4. The results suggest that overexpression of NEK2 has the potential to serve as a biomarker for PCa (show FLVCR1 ELISA Kits) prognosis.

  5. Nek2A is degraded in mitosis regardless of enforced spindle checkpoint activation

  6. we highlight recent findings on the aberrant expression and functional significance of NEK2A in human cancers and emphasize their significance for therapeutic potentials.

  7. Findings are consistent with the hypothesis that NEK2 contributes to ALDH1A1 (show ALDH1A1 ELISA Kits)-dependent drug resistance in myeloma

  8. Nek2 was demonstrated to phosphorylate Cep68 in vivo and this phosphorylation appears to promote Cep68 degradation in mitosis.

  9. Nek2 plays a central role in proteasome-mediated cell cycle regulation and in conferring resistance to bortezomib in cancer cells.

  10. High expression of Nek2 could serve as an independent predictor of poor prognosis in pancreatic ductal adenocarcinoma.

NEK2 Antigen Profile

Antigen Summary

This gene encodes a serine/threonine-protein kinase that is involved in mitotic regulation. This protein is localized to the centrosome, and undetectable during G1 phase, but accumulates progressively throughout the S phase, reaching maximal levels in late G2 phase. Alternatively spliced transcript variants encoding different isoforms with distinct C-termini have been noted for this gene.

Gene names and symbols associated with NEK2

  • NIMA (never in mitosis gene a)-related kinase 2 (NEK2) antibody
  • NIMA (never in mitosis gene a)-related expressed kinase 2 (Nek2) antibody
  • NIMA-related kinase 2 (NEK2) antibody
  • serine/threonine-protein kinase Nek2 (NEK2) antibody
  • AA617254 antibody
  • ATNEK2 antibody
  • C77054 antibody
  • HsPK21 antibody
  • NEK2A antibody
  • NIMA-RELATED KINASE2 antibody
  • NIMA-related kinase 2 antibody
  • NLK1 antibody
  • T9J14.24 antibody
  • T9J14_24 antibody

Protein level used designations for NEK2

NIMA (never in mitosis gene a)-related kinase 2 , NIMA - related expressed kinase 2 , NIMA-related expressed kinase 2 , NIMA-related kinase 2 , Nek2 kinase , never in mitosis A-related kinase 2 , nimA-related protein kinase 2 , serine/threonine-protein kinase Nek2 , serine/threonine protein kinase Nek2 , nimA-like protein kinase 1

GENE ID SPECIES
100540058 Meleagris gallopavo
18005 Mus musculus
114482 Rattus norvegicus
480021 Canis lupus familiaris
397258 Sus scrofa
523998 Bos taurus
4751 Homo sapiens
819641 Arabidopsis thaliana
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