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The protein encoded by NXT1 is located in the nuclear envelope. Additionally we are shipping NXT1 Antibodies (41) and many more products for this protein.
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in Drosophila primary spermatocytes, the transcription factor used to activate expression of a transcript, rather than the RNA sequence itself or the core transcription machinery, determines whether this expression requires Nxt1
Here, the authors identify cellular nuclear transport factor 2 (NTF2 (show NUTF2 Proteins))-like export protein 1 (NXT1) as a novel binding partner of nucleoprotein (NP) that stimulates NP-mediated nuclear export via the CRM1 (show XPO1 Proteins)-dependent pathway.
Complementary structural, biochemical and cellular techniques indicated that the formation of a symmetric RNA binding platform generated by dimerization of NXF1 (show NXF1 Proteins):NXT1 facilitates the recognition of CTE-RNA and promotes its nuclear export
regulation of tumor necrosis factor-alpha (show TNF Proteins) mRNA nucleocytoplasmic transport by ERK (show EPHB2 Proteins) map kinases requires TAP-NxT1 binding and the AU-rich element
The protein encoded by this gene is located in the nuclear envelope. It has protein similarity to nuclear transport factor 2. This protein functions as a nuclear export factor in both RAN (Ras-related nuclear protein)- and CRM1 (required for chromosome region maintenance)-dependent pathways. It is found to stimulate the export of U1 snRNA in RAN- and CRM1-dependent pathways and the export of tRNA and mRNA in a CRM1-independent pathway. The encoded protein heterodimerizes with Tap protein and may regulate the ability of Tap protein to mediate nuclear mRNA export. The use of alternate polyadenylation sites has been found for this gene.
, NTF2-related export protein 1
, NTX2-like export factor1
, NUTF-like export factor 1
, protein p15