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anti-Naked Cuticle Homolog 1 (Drosophila) (NKD1) Antibodies

In the mouse, Nkd is a Dishevelled (see DVL1; MIM 601365)-binding protein that functions as a negative regulator of the Wnt (see WNT1; MIM 164820)-beta-catenin (see MIM 116806)-Tcf (see MIM 602272) signaling pathway.. Additionally we are shipping Naked Cuticle Homolog 1 (Drosophila) Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NKD1 93960 Q99MH6
NKD1 85407 Q969G9
NKD1 364952  
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Top anti-Naked Cuticle Homolog 1 (Drosophila) Antibodies at antibodies-online.com

Showing 10 out of 28 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-NKD1 Antibody Titration: 0.2-1 ug/mlPositive Control: 721_B cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Mouse Rabbit Un-conjugated WB NKD1 Antibody (N-term) (ABIN657536) western blot analysis in mouse lung,heart,bladder tissue lysates (35 µg/lane). This demonstrates the NKD1 antibody detected the NKD1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC, WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Alkaline Phosphatase (AP) ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated WB NKD1 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Rabbit Un-conjugated IHC, WB NKD1 antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml to stain Alveolar cells (arrows) in Human Lung. Magnification is at 400X NKD1 antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml. Magnification is at 400X 50 μg Log in to see 3 to 4 Days
$473.93
Details

NKD1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)


Human ,


, , , , ,
Rat (Rattus)


Top referenced anti-Naked Cuticle Homolog 1 (Drosophila) Antibodies

  1. Chicken Polyclonal NKD1 Primary Antibody for IHC, WB - ABIN2776729 : Yan, Wiesmann, Rohan, Chan, Jefferson, Guo, Sakamoto, Caothien, Fuller, Reinhard, Garcia, Randazzo, Escobedo, Fantl, Williams: Elevated expression of axin2 and hnkd mRNA provides evidence that Wnt/beta -catenin signaling is activated in human colon tumors. in Proceedings of the National Academy of Sciences of the United States of America 2001 (PubMed)

More Antibodies against Naked Cuticle Homolog 1 (Drosophila) Interaction Partners

Mouse (Murine) Naked Cuticle Homolog 1 (Drosophila) (NKD1) interaction partners

  1. deletion of the EF-hand from Nkd1 reduces the number of the elongating spermatids at haploid stage

  2. Viable mice were obtained with compound mutations in the Wnt (show WNT2 Antibodies)/Dvl (show DVL1 Antibodies) pathway antagonists nkd1 and nkd2 (show NKD2 Antibodies).

Human Naked Cuticle Homolog 1 (Drosophila) (NKD1) interaction partners

  1. Suggest that NKD1 plays an important role in invasion in human breast cancer and it appears to be a potential prognostic marker for patients with breast cancer.

  2. Reduced NKD1 protein expression correlates with a poor prognosis in NSCLC

  3. Mutations in the human naked cuticle homolog NKD1 found in colorectal cancer alter Wnt (show WNT2 Antibodies)/Dvl (show DVL2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling

Zebrafish Naked Cuticle Homolog 1 (Drosophila) (NKD1) interaction partners

  1. Nkd1 activity is specifically dependent on Wnt (show WNT2 Antibodies) ligand activation of the receptor. Nkd1 is recruited to the Wnt (show WNT2 Antibodies) signalosome with Dvl2 (show DVL2 Antibodies), where it becomes activated to move into the cytoplasm to interact with beta-catenin (show CTNNB1 Antibodies), inhibiting its nuclear accumulation.

  2. Nkd1 functions as a passive antagonist of Wnt (show WNT2 Antibodies) signaling, functioning only when homeostatic levels of Wnt (show WNT2 Antibodies) signaling have been breached or when Wnt (show WNT2 Antibodies) signaling becomes destabilized.

  3. Data demonstrate that Nkd1 binds to beta-catenin (show CTNNB1 Antibodies) and prevents its nuclear accumulation. Nkd1 function is dependent on its interaction with the cell membrane.

  4. Nkd1 knockdown in the dorsal forerunner cells causes beta-catenin (show CTNNB1 Antibodies) nuclear localization/transcriptional activation & changes in DFC migration, Kupffer's vesicle formation, ciliogenesis, left-right patterning, & asymmetric charon expression.

  5. data indicate that zebrafish Nkd1 and Nkd2 (show NKD2 Antibodies) function to limit both canonical and non-canonical Wnt (show WNT2 Antibodies) signaling

Naked Cuticle Homolog 1 (Drosophila) (NKD1) Antigen Profile

Protein Summary

In the mouse, Nkd is a Dishevelled (see DVL1\; MIM 601365)-binding protein that functions as a negative regulator of the Wnt (see WNT1\; MIM 164820)-beta-catenin (see MIM 116806)-Tcf (see MIM 602272) signaling pathway.

Gene names and symbols associated with NKD1

  • naked cuticle homolog 1 (Drosophila) (NKD1) antibody
  • naked cuticle 1 homolog (Drosophila) (Nkd1) antibody
  • naked cuticle homolog 1 (Drosophila) (Nkd1) antibody
  • naked cuticle homolog 1 (Drosophila) (nkd1) antibody
  • 2810434J10Rik antibody
  • 9030215G15Rik antibody
  • Naked1 antibody
  • Nkd antibody

Protein level used designations for NKD1

naked cuticle homolog 1 (Drosophila) , mNkd , mNkd1 , naked-1 , protein naked cuticle homolog 1 , Dvl-binding protein , naked cuticle-1 , naked cuticle 1 homolog , naked 1

GENE ID SPECIES
487288 Canis lupus familiaris
93960 Mus musculus
415729 Gallus gallus
85407 Homo sapiens
618586 Bos taurus
364952 Rattus norvegicus
751108 Danio rerio
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