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anti-Nardilysin (N-Arginine Dibasic Convertase) (NRD1) Antibodies

NRD1 encodes a zinc-dependent endopeptidase that cleaves peptide substrates at the N-terminus of arginine residues in dibasic moieties and is a member of the peptidase M16 family. Additionally we are shipping NRD1 Proteins (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NRD1 4898 O43847
NRD1 25499 P47245
NRD1 230598 Q8BHG1
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Top anti-NRD1 Antibodies at antibodies-online.com

Showing 10 out of 31 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-NRD1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: HepG2 cell lysate WB Suggested Anti-NRD1  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500  Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB NRD1 Antibody (Center) (ABIN657969) western blot analysis in NCI-H460 cell line lysates (35 µg/lane). This demonstrates the NRD1 antibody detected the NRD1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Alkaline Phosphatase (AP) ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Rat Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 8 to 10 Days
$449.17
Details
Rat Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 8 to 10 Days
$449.17
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated WB NRD1 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (37 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details

NRD1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,
,

, , , , ,
Rat (Rattus) ,


Mouse (Murine)


Top referenced anti-NRD1 Antibodies

  1. Human Polyclonal NRD1 Primary Antibody for WB - ABIN657969 : Bernstein, Stricker, Dobrowolny, Trübner, Bogerts, Reiser: Histochemical evidence for wide expression of the metalloendopeptidase nardilysin in human brain neurons. in Neuroscience 2007 (PubMed)
    Show all 2 references for ABIN657969

  2. Human Polyclonal NRD1 Primary Antibody for WB - ABIN2787813 : Hiraoka, Yoshida, Ohno, Matsuoka, Kita, Nishi: Ectodomain shedding of TNF-alpha is enhanced by nardilysin via activation of ADAM proteases. in Biochemical and biophysical research communications 2008 (PubMed)

More Antibodies against NRD1 Interaction Partners

Human Nardilysin (N-Arginine Dibasic Convertase) (NRD1) interaction partners

  1. MRNA expression of NRD1 was upregulated in 56% of ESCC tissue samples.

  2. This study demonistrated that alcohol-dependent reduction of nardilysin in cell culture and nervous tissue points to an implication of the enzyme in the pathophysiology of alcoholism.

  3. possible roles of nardilysin in Alzheimer disease, Down syndrome, schizophrenia, mood disorders, alcohol abuse, heroin addiction and cancer; show that nardilysin is a Janus-faced enzyme with regard to brain pathology-- probably neuropathogenic in some diseases, but neuroprotective in others [review]

  4. SH-SY5Y cells, stably transfected with green fluorescent protein-tagged-p42 (show EPB42 Antibodies)(IP4) show enhanced NRD (show PRDM1 Antibodies) protein expression already at an earlier time point after retinoic acid stimulation.

  5. NRD1 interacts with p53 (show TP53 Antibodies) mutant R273H

  6. These results demonstrate that gastric cancer cell growth is maintained by autonomous TNF-alpha (show TNF Antibodies)-NF-kappaB (show NFKB1 Antibodies) and IL-6 (show IL6 Antibodies)-STAT3 (show STAT3 Antibodies) signalling, and that NRDc and ADAM proteases turn on these signalling cascades by stimulating ectodomain shedding of TNF-alpha (show TNF Antibodies).

  7. Identification and characterization of nardilysin as a novel dimethyl H3K4-binding protein involved in transcriptional regulation.

  8. Several flanking SNPs of the top hits in the meta-analysis demonstrated borderline associations with alcohol dependence in the family sample for KIAA0040, NRD1 and THSD7B, respectively.

  9. Tubulin (show TUBB Antibodies) potentiates the interaction of the metalloendopeptidase (show THOP1 Antibodies) nardilysin with the neuronal scaffold protein (show HOMER1 Antibodies) p42IP4 (show ADAP1 Antibodies)/centaurin-alpha1 (ADAP1 (show ADAP1 Antibodies)).

  10. nardilysin (NRDc) is potently inhibited by heparin-binding epidermal growth factor-like growth factor (HB-EGF (show HBEGF Antibodies))

Mouse (Murine) Nardilysin (N-Arginine Dibasic Convertase) (NRD1) interaction partners

  1. deletion of nardilysin prevents the development of diet-induced steatohepatitis and liver fibrogenesis

  2. Identification and characterization of nardilysin as a novel dimethyl H3K4-binding protein involved in transcriptional regulation.

  3. The use of proteolysis to study the structure of nardilysin.

  4. Studies extend the range of potential substrates for nardilysin and further substantiate that nardilysin is a true peptidase.

  5. miniglucagon-generating endopeptidase is composed of NRDc and aminopeptidase B (show RNPEP Antibodies) acting sequentially

  6. role for nardilysin in oocyte meiosis through its dynamic translocation from cytosol to nucleus, and then to the spindle apparatus

  7. NRDc regulates axonal maturation and myelination in the nervous system, in part, through the modulation of NRG1 (show NRG1 Antibodies) shedding

  8. The acidic stretch of nardilysin, expressed as a fusion protein with glutathione S-transferase (show GSTa2 Antibodies) and compared to the native enzyme with respect to spermine binding, functions as an autonomous domain.

NRD1 Antigen Profile

Protein Summary

This gene encodes a zinc-dependent endopeptidase that cleaves peptide substrates at the N-terminus of arginine residues in dibasic moieties and is a member of the peptidase M16 family. This protein interacts with heparin-binding EGF-like growth factor and plays a role in cell migration and proliferation. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with NRD1

  • nardilysin (N-arginine dibasic convertase) (NRD1) antibody
  • nardilysin (N-arginine dibasic convertase) (nrd1) antibody
  • nardilysin (CpipJ_CPIJ002524) antibody
  • nardilysin (Tsp_03755) antibody
  • nardilysin 1 (Nrd1) antibody
  • nardilysin, N-arginine dibasic convertase, NRD convertase 1 (Nrd1) antibody
  • 2600011I06Rik antibody
  • AI875733 antibody
  • DKFZp459N143 antibody
  • hNRD1 antibody
  • hNRD2 antibody
  • Nardilysin antibody
  • NRD-C antibody
  • NRD1 antibody
  • NRDC antibody
  • si:dkey-171o17.4 antibody

Protein level used designations for NRD1

nardilysin , nardilysin (N-arginine dibasic convertase) , NRD convertase , N-arginine dibasic convertase , NRD-C , N-arginine dibasic convertase 1 , nardilysin 1 (N-arginine dibasic convertase) , nardilysin, N-arginine dibasic convertase 1 , nardilysin, N-arginine dibasic convertase, NRD convertase 1

GENE ID SPECIES
424635 Gallus gallus
456852 Pan troglodytes
475354 Canis lupus familiaris
552055 Apis mellifera
557565 Danio rerio
6033791 Culex quinquefasciatus
10910482 Trichinella spiralis
100173985 Pongo abelii
100452780 Pongo abelii
100514906 Sus scrofa
4898 Homo sapiens
25499 Rattus norvegicus
230598 Mus musculus
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