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Natriuretic Peptide A Proteins (NPPA)

The protein encoded by NPPA belongs to the natriuretic peptide family. Additionally we are shipping Natriuretic Peptide A Antibodies (122) and Natriuretic Peptide A Kits (39) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NPPA 24602 P01161
NPPA 4878 P01160
Mouse NPPA NPPA 230899 P05125
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Top Natriuretic Peptide A Proteins at antibodies-online.com

Showing 2 out of 2 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Rat GST tag 100 μg Log in to see 11 to 13 Days
$704.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
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NPPA Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus)

Human

More Proteins for Natriuretic Peptide A (NPPA) Interaction Partners

Rainbow Trout (Oncorhynchus mykiss) Natriuretic Peptide A (NPPA) interaction partners

  1. Expression of atrial natriuretic peptide, C-type natriuretic peptide-1, and the guanylyl cyclase-linked (GC) natriuretic peptide receptor-A (show NPR1 Proteins) and -B-type receptors was determined by PCR from the mRNA of head kidney leucocytes

Pig (Porcine) Natriuretic Peptide A (NPPA) interaction partners

  1. Atrial natriuretic peptide and vasopressin (show AVP Proteins)-presence in the ciliary body of eye in the pig (sus domesticus).

  2. ANP and BNP gene expression differs considerably between cardiac chambers in the first 72 hours of life in healthy piglets, resembling the transition from fetal to neonate circulation. The cardiac gene expression does not explain plasma concentrations.

  3. Up-regulation of ANP and a reduction in a ratio of sarcoplasmic reticulum calcium ATPase 2a and phospholamban (show PLN Proteins) in failing myocardium are observed in a porcine model of tachycardia.

  4. Arial natriuretic factor (ANF (show HESX1 Proteins)) and N-terminal proANF may be better suited than brain natriuretic peptide (show BNP Proteins) as markers of cardiac preload during the development and treatment of acute heart failure.

  5. Stimulation of prepubertal granulosa cells with FSH (show BRD2 Proteins) resulted in a moderate expression of ANP. When FSH (show BRD2 Proteins) treatment was followed by LH, the pronounced expression of ANP was observed in all cells.

Horse (Equine) Natriuretic Peptide A (NPPA) interaction partners

  1. ANP in plasma is increased in horses with heart disease associated with altered left-sided chamber dimensions and/or function.

  2. Cardiac ANP was increased in horses with mitral regurgitation (MR) and cardiac troponin levels were low in healthy and MR affected horses.

Human Natriuretic Peptide A (NPPA) interaction partners

  1. C2238/alphaANP downregulates ApoE (show APOE Proteins) in vascular smooth muscle cells through type C natriuretic peptide receptor-dependent activation of Egr-1 (show EGR1 Proteins) and the consequent upregulation of miR199a.

  2. ANP levels rose steeply after paroxysmal supraventricular tachycardia and then reduced at 30 min after the termination.

  3. Age-related elevation of plasma ANP levels preceded the development of CKD in the general population of Japan, raising a possibility for ANP being involved in the development of CKD.

  4. Circulating atrial natriuretic peptide genetic association study identifies a novel gene cluster associated with stroke in whites.

  5. In this review, we discuss the role of ANP in cardiovascular biology and disease.

  6. Our results suggest that the down-regulation of ANP gene expression at mRNA and protein levels and up-regulated CYP11B2 (show CYP11B2 Proteins) protein expression levels may be correlated with the essential hypertension

  7. Three NPPA-NPPB polymorphisms (rs632793, rs198388 and rs198389) were associated with reduced risk of left ventricular dysfunction in CAD patients with hyperlipidemia.

  8. plasma mid-regional pro-atrial natriuretic peptide helps predict pre-eclampsia

  9. ANP is present in chondrocytes in all the three zones of the articular cartilage, sugesting that ANP may play a role in cartilage metabolism.

  10. ANP prevents cancer metastasis by inhibiting the adhesion of tumor cells to inflamed endothelial cells

Cow (Bovine) Natriuretic Peptide A (NPPA) interaction partners

  1. ANP acts as an anti-permeability factor by inhibiting the signaling functions of vascular permeability factor (show VEGFA Proteins) and by preserving the endothelial cell tight junctions functional morphology

Rabbit Natriuretic Peptide A (NPPA) interaction partners

  1. These studies support the therapeutic potential of dual inhibition of NEP (show MME Proteins) and ACE (show ACE Proteins) in the prevention of increased arterial ECP (show ECP Proteins) and atherogenesis which may be linked to the ANP/cGMP system.

  2. Diabetes may modify the vascular actions of ANP in isolated rabbit carotid arteries and the mechanisms involved in these actions; ANP induces relaxation of precontracted carotid arteries, which is lower in diabetic than in control rabbits.

  3. The study suggests that Beta1-adrenergic receptor activation decreases atrial natriuretic peptide release via cAMP- and Ca(2 (show CA2 Proteins)+)-dependent mechanisms.

Mouse (Murine) Natriuretic Peptide A (NPPA) interaction partners

  1. Data (including data from studies in knockout mice) suggest expression of ANP/BNP/GC-A (show GUCA1A Proteins) (atrial natriuretic peptide, brain natriuretic peptide (show BNP Proteins), and guanylyl cyclase-A (show NPR1 Proteins)) is important in embryonic neovascularization and organogenesis.

  2. Goalpha plays a role in ANF sorting during intracellular vectorial transport and with the presence of a mechanism that preserves the molar relationship between cellular ANF and BNP.

  3. ANP prevents cancer metastasis by inhibiting the adhesion of tumor cells to inflamed endothelial cells

  4. Expression of NPPA splice variants is differentially regulated in the developing mouse heart.

  5. NPPA acts on the NPR1 receptor, is expressed in mouse dorsal root and trigeminal ganglia, and the spinal cord.

  6. Natriuretic peptides buffer renin (show REN Proteins)-dependent hypertension.

  7. Data indicate that the identified stress-responsive enhancer of Nppa and Nppb (show BNP Proteins), the most common markers of heart failure, is a 650-bp fragment within 50 kb of the Nppa and Nppb (show BNP Proteins) loci.

  8. Absence of maternal atrial natriuretic peptide leads to gestational hypertension and adaptive changes fetal cardiac growth and blood pressure regulation.

  9. This study investigated a novel mechanism of vascular barrier protection by ANP via modulation of GEF-H1 (show ARHGEF2 Proteins) function.

  10. Data indicate that NRG-1beta up-regulated the gene expressions of Nkx2.5, GATA4, alpha-actin, MLC-2v, and ANF in a time-dependent regulation of ErbB/ERK1/2 pathways.

Natriuretic Peptide A (NPPA) Protein Profile

Protein Summary

The protein encoded by this gene belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is processed to release a peptide from the N-terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C-terminus with natriuretic-diuretic activity. Mutations in this gene have been associated with atrial fibrillation familial type 6.

Gene names and symbols associated with Natriuretic Peptide A Proteins (NPPA)

  • atrial natriuretic peptide (anp)
  • atrial natriuretic peptide (nppa)
  • natriuretic peptide A (NPPA)
  • natriuretic peptide A (Nppa)
  • natriuretic peptide B (NPPB)
  • natriuretic peptide type A (Nppa)
  • Anf protein
  • ANP protein
  • ATFB6 protein
  • CDD-ANF protein
  • NPPA protein
  • PND protein
  • RATANF protein

Protein level used designations for Natriuretic Peptide A Proteins (NPPA)

atrial natriuretic peptide , ANF , atrial natriuretic factor , natriuretic peptides A , prepronatriodilatin , natriuretic peptide precursor A , ANP , prohormone for atrial natriuretic polypeptide (ANP) , Natriuretic peptide precursor A (pronatriodilatin, also Anf, Pnd) , natriuretic peptide precursor type A , atriopeptin , cardionatrin , Atrial natriuretic factor , Atrial natriuretic peptide , Prepronatriodilatin , natriuretic peptide type A , Natriuretic peptides A

GENE ID SPECIES
100135815 Oncorhynchus mykiss
445903 Takifugu rubripes
608289 Canis lupus familiaris
397496 Sus scrofa
100034201 Equus caballus
24602 Rattus norvegicus
4878 Homo sapiens
281355 Bos taurus
100009087 Oryctolagus cuniculus
100294648 Ovis aries
100135578 Cavia porcellus
101100575 Felis catus
395765 Gallus gallus
230899 Mus musculus
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