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NES encodes a member of the intermediate filament protein family and is expressed primarily in nerve cells. Additionally we are shipping Nestin Antibodies (332) and Nestin Proteins (7) and many more products for this protein.
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The authors found that high/positive SOX2 (show SOX2 ELISA Kits) alterations, either DNA amplification or protein expression, were favorable for overall survival (OS) in non-small cell lung cancer. On the contrary, high/positive Nestin protein expression was poor for OS.
Study clarified the relationship between Nestin overexpression and poor prognosis in recurrent human hepatocellular carcinoma (HCC (show FAM126A ELISA Kits)) patients receiving FOLFOX regimen, and its association with chemoresistance and epithelial-mesenchymal transition in HCC (show FAM126A ELISA Kits) cell lines.
Results show that the positive rates and expression levels of nestin, tyrosine hydroxylase (TH (show TH ELISA Kits)), GFAP (show GFAP ELISA Kits) and IL-17 (show IL17A ELISA Kits) were significantly decreased while Foxp3 (show FOXP3 ELISA Kits) and the ratio of Foxp3 (show FOXP3 ELISA Kits)/IL-17 (show IL17A ELISA Kits) were statistically elevated in BM of AML (show RUNX1 ELISA Kits) patients.
Nestin may have an important role in GIST malignancy by regulating mitochondrial dynamics and altering intracellular ROS (show ROS1 ELISA Kits) levels. The findings provide new clues to reveal mechanisms by which nestin mediates the proliferation and invasion of GISTs.
he present study reveals that nestin expression is a prognostic indicator of a poorer survival probability in NSCLC patients receiving adjuvant platinum-based chemotherapy , although its prognostic significance still requires confirmation with larger patient populations
Data suggest that negative feedback mediated by GLI3 (show GLI3 ELISA Kits) (GLI (show GLI1 ELISA Kits)-Kruppel family member) acts to finely tune SHH (sonic hedgehog (show SHH ELISA Kits)) signaling. During medulloblastoma (MB) formation, nerve tissue cells appear to express nestin which hyperactivates SHH (show SHH ELISA Kits) signaling by abolishing negative feedback by GLI3 (show GLI3 ELISA Kits). Restoration of intrinsic negative feedback by repressing nestin expression represents a promising approach to treat MB. [REVIEW]
the induction of P-gp (show ABCB4 ELISA Kits) expression is causally associated with the expression of nestin in leukemia cells
SRY (sex determining region Y)-box 10 (show SOX10 ELISA Kits) protein (SOX10 (show SOX10 ELISA Kits)) enhances nestin protein (NES) expression via directly binding to the promoter of NES.
Immunohistochemical assessment of nestin and INPP4b (show INPP4B ELISA Kits) provides an accurate, accessible and inexpensive tool to identify basal-like breast cancer subtype in the clinically problematic setting of weak oestrogen receptor positivity
Tumor expression of nestin might be a valuable prognostic factor for survival in patients with advanced ovarian cancer. With regard to its endothelial expression, nestin might be as reliable as CD34 (show CD34 ELISA Kits) for quantifying tumor angiogenesis.
Nestin regulates neural stem cell migration via controlling the cell contractility
demonstrate that following postnatal ablation of granule cell progenitors, Nestin-expressing progenitors, specified during mid-embryogenesis to produce astroglia and interneurons, switch their fate and generate granule neurons in mice.
The nestin(+) cells contribute to all subsets of the complex stromal populations that can be found in lymph nodes.
nestin may label progenitor cells during inner ear development and may not be a stem cell marker in the mature organ of Corti
Nestin(+) cells are one important type of progenitor cell in bone marrow and are associated with bone remodeling. These data indicate that DMP1 (show DMP1 ELISA Kits) plays negative roles in differentiation of Nestin(+) cells and bone formation.
Our findings show how Nestin drives hedgehog (show SHH ELISA Kits) pathway-driven cancers and the tumor-promoting effects of Nestin were mediated by binding to Gli3 (show GLI3 ELISA Kits), a zinc finger transcription factor (show OSR1 ELISA Kits) that negatively regulates hedgehog (show SHH ELISA Kits) signaling.
Based on a nestin-green fluorescent protein (NGFP) transgenic model, a histological inventory has been performed to deliver an overview of neuronal and glial markers for the various parts of the gastrointestinal tract in newborn (postnatal day 7) and adult mice under homeostatic conditions.
EGFR (show EGFR ELISA Kits) and Nestin showed to have vital role during mice development, and considered to be suitable markers for the study of skin stem cells.
Nestin was shown to affect cell number and was significantly enhanced in lungs early during development of pulmonary hypertension.
Chromatin Remodeling Factor (show ASH1L ELISA Kits) Brg1 (show SMARCA4 ELISA Kits) Supports the Early Maintenance and Late Responsiveness of Nestin-Lineage Adult Neural Stem and Progenitor Cells.
Nestin gene may serve as a marker for stem cells and proliferating precursors in the developing embryonic nervous system as well as in the postembryonic brain[Nestin]
Results suggest that nestin is essential for brain and eye development probably through control of progenitor cell apoptosis.
Cells expressing the two reporters display radial glial morphology, colocalize with the NSC marker Sox2 (show SOX2 ELISA Kits), undergo proliferation, and are capable of self-renewal within the matrix of distinct thickness in the telencephalon.
This gene encodes a member of the intermediate filament protein family and is expressed primarily in nerve cells.
, intermediate filament protein