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anti-Neural Precursor Cell Expressed, Developmentally Down-Regulated 1 (NEDD1) Antibodies

Required for mitosis progression. Additionally we are shipping NEDD1 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NEDD1 121441 Q8NHV4
NEDD1 299730  
NEDD1 17997 P33215
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Top anti-NEDD1 Antibodies at antibodies-online.com

Showing 10 out of 56 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-NEDD1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:2500Positive Control: Human Spleen 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA, WB ABIN334442 (0.1µg/ml) staining of HeLa cell lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Goat Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to NEDD1 on formalin-fixed paraffin-embedded human placenta. [antibody concentration 0.75 ug/ml] NEDD1 monoclonal antibody (M05), clone 7D10 Western Blot analysis of NEDD1 expression in Hela NE 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB Anti-NEDD1 in Western Blot using Immunochemical Anti-NEDD1 Antibody shows detection of a 73 kDa band corresponding to endogenous NEDD1 in lysates of S phase HeLa cells silenced for either control Luciferase or NEDD1. In right lane (NEDD1i): lysates from sh-NEDD1 RNAi-treated lentivirus-infected cells. In left lane (GLi): lysates from sh-Luciferase lentivirus-infected cells as control. Anti-NEDD1 Antibody was used at 1:10,000. Molecular weight estimation was made by comparison by prestained MW markers. ECL was used for detection. 25 μL Log in to see 2 to 3 Days
$135.00
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Mouse Un-conjugated WB NEDD1 monoclonal antibody (M05), clone 7D10 Western Blot analysis of NEDD1 expression in Hela NE on formalin-fixed paraffin-embedded human placenta (antibody concentration 0.75 µg/mL). 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 8 to 10 Days
$610.50
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB 100 μg Log in to see 8 to 10 Days
$537.17
Details

NEDD1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-NEDD1 Antibodies

  1. Human Monoclonal NEDD1 Primary Antibody for IHC (p), ELISA - ABIN566771 : Zhu, Coppinger, Jang, Yates, Fang: FAM29A promotes microtubule amplification via recruitment of the NEDD1-gamma-tubulin complex to the mitotic spindle. in The Journal of cell biology 2008 (PubMed)
    Show all 8 references for ABIN566771

  2. Chicken Polyclonal NEDD1 Primary Antibody for WB - ABIN2785241 : Haren, Remy, Bazin, Callebaut, Wright, Merdes: NEDD1-dependent recruitment of the gamma-tubulin ring complex to the centrosome is necessary for centriole duplication and spindle assembly. in The Journal of cell biology 2006 (PubMed)

More Antibodies against NEDD1 Interaction Partners

Xenopus laevis Neural Precursor Cell Expressed, Developmentally Down-Regulated 1 (NEDD1) interaction partners

  1. This study identifies TPX2 as the only direct RanGTP target and NEDD1 as the only Aurora A (show AURKA Antibodies) substrate essential for the activation of the RanGTP-dependent microtubule nucleation pathway.

Human Neural Precursor Cell Expressed, Developmentally Down-Regulated 1 (NEDD1) interaction partners

  1. One important function of Aurora A (show AURKA Antibodies) in mitotic cells is to promote microtubule nucleation around the chromatin by phosphorylating NEDD1, and thereby to promote functional spindle assembly.

  2. The mice treated with small interfering (si) RNA targeting NEDD1 by the atelocollagen-mediated delivery system showed a significantly prolonged survival in a xenograft model of human gastric cancer.

  3. Data suggest that the NEDD1/gamma-tubulin (show TUBG1 Antibodies) interaction is finely tuned by multiple phosphorylation events in the S557-S574 region and is critical for spindle assembly.

  4. Nek9 (show NEK9 Antibodies) phosphorylates NEDD1 on Ser377 driving its recruitment and thereby that of gamma-tubulin (show TUBG1 Antibodies) to the centrosome in mitotic cells.

  5. a direct interaction with NEDD1 regulates gamma-tubulin (show TUBG1 Antibodies) recruitment to the centrosome

  6. GCP-WD (NEDD1) broadly mediates targeting of the gamma-tubulin (show TUBG1 Antibodies) ring complex to sites of microtubule nucleation and to the mitotic spindle, which is essential for spindle formation.

  7. FAM29A (show HAUS6 Antibodies) promotes microtubule amplification via recruitment of the NEDD1-gamma-tubulin (show TUBG1 Antibodies) complex to the mitotic spindle.

  8. Data propose NEDD1 may be a promising target for controlling cell proliferation, in particular if targeted in combination with Plk1 (show PLK1 Antibodies) inhibitors.

  9. Data suggest that sequential phosphorylation of Nedd1 by Cdk1 (show CDK1 Antibodies) and Plk1 (show PLK1 Antibodies) plays a role in targeting gamma tubulin (show TUBG1 Antibodies) ring complex to the centrosome by promoting the interaction of Nedd1 with the gammaTuRC component gamma-tubulin (show TUBG1 Antibodies), during mitosis.

Mouse (Murine) Neural Precursor Cell Expressed, Developmentally Down-Regulated 1 (NEDD1) interaction partners

  1. The mice treated with small interfering (si) RNA targeting NEDD1 by the atelocollagen-mediated delivery system showed a significantly prolonged survival.

  2. Disrupting the centrosome in early-passage mouse embryonic fibroblasts by depletion of NEDD1 also resulted in centrosomal fragmentation and subsequent premature entry into senescence.

  3. a direct interaction with NEDD1 regulates gamma-tubulin (show TUBG1 Antibodies) recruitment to the centrosome

  4. NEDD1 is an essential component of acentriolar oocyte MTOCs, which functions in the regulation of meiotic spindle stability

  5. the localization of Nedd1 and the centrosome during important processes in mouse embryogenesis and provides a basis for further study into its role in development.

NEDD1 Antigen Profile

Protein Summary

Required for mitosis progression. Promotes the nucleation of microtubules from the spindle (By similarity). May play an important role during the embryonic development and differentiation of the central nervous system.

Gene names and symbols associated with NEDD1

  • neural precursor cell expressed, developmentally down-regulated 1 (nedd1) antibody
  • neural precursor cell expressed, developmentally down-regulated 1 (NEDD1) antibody
  • neural precursor cell expressed, developmentally down-regulated 1 (Nedd1) antibody
  • neural precursor cell expressed, developmentally down-regulated gene 1 (Nedd1) antibody
  • GCP-WD antibody
  • MGC81767 antibody
  • MGC145237 antibody
  • TUBGCP7 antibody

Protein level used designations for NEDD1

neural precursor cell expressed, developmentally down-regulated 1 , NEDD-1 , neural precursor cell expressed developmentally down-regulated protein 1 , protein NEDD1 , neural precursor cell expressed, developmentally down-regulated gene 1

GENE ID SPECIES
447718 Xenopus laevis
779911 Xenopus (Silurana) tropicalis
100548421 Meleagris gallopavo
121441 Homo sapiens
417922 Gallus gallus
482616 Canis lupus familiaris
519463 Bos taurus
299730 Rattus norvegicus
17997 Mus musculus
Selected quality suppliers for anti-NEDD1 (NEDD1) Antibodies
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