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Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Additionally we are shipping Neurofilament Triplet M Protein Kits (22) and Neurofilament Triplet M Protein Proteins (11) and many more products for this protein.
Showing 10 out of 218 products:
Bird (Avian) Polyclonal NEFM Primary Antibody for ICC, IHC (fro) - ABIN152479
Skaat, Ziv-Polat, Shahar, Margel: Enhancement of the growth and differentiation of nasal olfactory mucosa cells by the conjugation of growth factors to functional nanoparticles. in Bioconjugate chemistry 2011
Show all 6 references for ABIN152479
Chicken Polyclonal NEFM Primary Antibody for ICC, IF - ABIN152562
Portmann-Lanz, Schoeberlein, Portmann, Mohr, Rollini, Sager, Surbek: Turning placenta into brain: placental mesenchymal stem cells differentiate into neurons and oligodendrocytes. in American journal of obstetrics and gynecology 2010
Show all 3 references for ABIN152562
Chicken Monoclonal NEFM Primary Antibody for WB - ABIN967356
Fernyhough, Gallagher, Averill, Priestley, Hounsom, Patel, Tomlinson: Aberrant neurofilament phosphorylation in sensory neurons of rats with diabetic neuropathy. in Diabetes 1999
Show all 2 references for ABIN967356
Chicken Polyclonal NEFM Primary Antibody for FACS, IF (cc) - ABIN672186
Gao, Bai, Xiong, Li, Shan, Huang, Ma, Guan: Isolation and characterization of chicken dermis-derived mesenchymal stem/progenitor cells. in BioMed research international 2013
Mouse (Murine) Polyclonal NEFM Primary Antibody for ELISA, WB - ABIN4339223
Levy, Liem, DEustachio, Cowan: Structure and evolutionary origin of the gene encoding mouse NF-M, the middle-molecular-mass neurofilament protein. in European journal of biochemistry 1987
Chicken Monoclonal NEFM Primary Antibody for IF, WB - ABIN371828
Harris, Ayyub, Shaw: A molecular dissection of the carboxyterminal tails of the major neurofilament subunits NF-M and NF-H. in Journal of neuroscience research 1992
Bird (Avian) Monoclonal NEFM Primary Antibody for ICC, IF - ABIN152480
Sikora, Leddy, Gulinello, Walkley: X-linked Christianson syndrome: heterozygous female Slc9a6 knockout mice develop mosaic neuropathological changes and related behavioral abnormalities. in Disease models & mechanisms 2016
All Species Monoclonal NEFM Primary Antibody for IF, IHC (p) - ABIN120651
Dráberová, Sulimenko, Kukharskyy, Dráber: Monoclonal antibody NF-09 specific for neurofilament protein NF-M. in Folia biologica 2000
Hamster Monoclonal NEFM Primary Antibody for IHC (fro), IF - ABIN112357
Bauwens, De Groot, Ramaekers, Veldman, Huizing: Expression of intermediate filament proteins in the adult human vestibular labyrinth. in The Annals of otology, rhinology, and laryngology 1992
Gene deletion studies demonstrated for the first time that lack of NFM (show CEBPB Antibodies) leads to changes of D1R (show DRD1 Antibodies)-mediated long-term potentiation and D1R (show DRD1 Antibodies)-mediated behavior
Data conclude that NF-H (show NEFH Antibodies) and NF-M (show CEBPB Antibodies) C-terminal domains do not normally regulate NF transport rates as previously proposed, but instead increase the proteolytic resistance of NF, thereby stabilizing the stationary neurofilament cytoskeleton along axons.
Computational modeling predicted that an expanded NF-M C terminus extended farther from the neurofilament core independent of lysine-serine-proline (KSP) phosphorylation.
results obtained in mouse model for leprous neuropathy indicate biochemical alterations in neurofilaments, i.e., hyperphosphorylation of NF-H (show NEFH Antibodies) and NF-M (show CEBPB Antibodies)
Data show that the tail domain of neurofilament subunit NF-M (show CEBPB Antibodies), with seven KSP motifs, is an essential target for the myelination-dependent outside-in signaling cascade that determines axonal caliber and conduction velocity of motor axons.
results demonstrate NF-M (show CEBPB Antibodies) tail-mediated interactions of neurofilaments, independent of NF transport rate, are critical determinants of the size and cytoskeletal architecture of axons and are mediated in part by the highly phosphorylated tail domain of NF-M (show CEBPB Antibodies)
NF-M regulates the association of NFs with kinesin.
Alpha-internexin (show INA Antibodies) coassembles with all 3 neurofilament proteins into a single network of filaments in quadruple-transfected cells. Deleting NF-M (show CEBPB Antibodies) alone or together with NF-H (show NEFH Antibodies) in mice reduces alpha-internexin (show INA Antibodies) transport & content in axons throughout the CNS.
data indicate that a blockade of NMDA receptors during development of cortical neurons increases the phosphorylation state and the solubility of NF-M (show CEBPB Antibodies), thereby favoring neurite outgrowth
Phosphorylation of NF-M (show CEBPB Antibodies) lysine-serine-proline (KSP) repeats is not an essential component for the acquisition of normal axonal caliber mediated by myelin-dependent outside-in signaling.
direct evidence that NF-M/H are hyperphosphorylated in Alzheimer disease
the importance of alpha-internexin (show INA Antibodies) and NF-L (show NEFL Antibodies) in regulating the conformations of NF-M and NF-H (show NEFH Antibodies)
To study if the increase of levels of neurofilament (NF)-M and NF-L (show NEFL Antibodies) in brain of Alzheimer's diseases (AD) is caused by increase of NF-M and NF-L (show NEFL Antibodies).
Two polymorphisms of neurofilament M(Ala475Thr and Gly697Arg) occurred at similar frequencies in PD patients and controls. A Pro725Gln substitution and a deletion of valine in position 829 were identified in two PD patients.
O-glycosylation of NF-M is highly dynamic and closely interwoven with phosphorylation cascades and may have a pathophysiological role.
variation in NEF3 influence rate of response to typical antipsychotic medication
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
neurofilament protein M
, neurofilament, medium polypeptide 150kDa
, neurofilament triplet M protein
, CCAAT box/enhancer binding protein beta
, CCAAT/enhancer-binding protein beta
, CCR protein
, c/EBP beta
, transcription factor NF-M
, 160 kDa neurofilament protein
, major neuronal intermediate filament subunit
, neurofilament 3
, neurofilament M subunit
, neurofilament medium polypeptide
, Neurofilament protein, middle polypeptide
, neurofilament 3, medium
, neurofilament-3 (150 kD medium)
, NF-M c-terminus
, NF-M protein
, neurofilament 3 (150kDa medium)
, middle molecular weight neurofilament protein NF-M(1)