NEFM antibody (AA 200-300)

Catalog No. ABIN7268865

The Rabbit Polyclonal anti-NEFM antibody (ABIN7268865) specifically detects NEFM in WB, IHC and IF. The antibody is reactive with Human samples.

Quick Overview for NEFM antibody (AA 200-300) (ABIN7268865)

Target: NEFM (Neurofilament Triplet M Protein (NEFM))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NEFM antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-NEFM Antibody

Binding Specificity: AA 200-300

Purpose: Neurofilament M Rabbit pAb

Sequence: EAAIRALRKD IEEASLVKVE LDKKVQSLQD EVAFLRSNHE EEVADLLAQI QASHITVERK DYLKTDISTA LKEIRSQLES HSDQNMHQAE EWFKCRYAKL T

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 200-300 of human Neurofilament M (NP_005373.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NEFM

Target: NEFM (Neurofilament Triplet M Protein (NEFM))

Alternative Name: NEFM

Background: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms.,NEF3,NF-M,NFM,NEFM,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Intermediate Filaments,Neuroscience,Cell Type Marker,Neurodegenerative Diseases,Neuron marker,NEFM

Molecular Weight: 59kDa/102kDa

Gene ID: 4741

UniProt: P07197

Pathways: Brown Fat Cell Differentiation