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Neuronatin Proteins (NNAT)

The protein encoded by NNAT is a proteolipid that may be involved in the regulation of ion channels during brain development. Additionally we are shipping Neuronatin Antibodies (6) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NNAT 4826 Q16517
NNAT 18111 Q61979
NNAT 94270 Q62649
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Top Neuronatin Proteins at antibodies-online.com

Showing 7 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,115.67
Details
Yeast Mesocricetus auratus His tag   1 mg Log in to see 56 to 66 Days
$2,115.67
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$2,115.67
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,115.67
Details

NNAT Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for Neuronatin (NNAT) Interaction Partners

Human Neuronatin (NNAT) interaction partners

  1. Data suggest NNAT as a potential tumor suppressor in myxoid liposarcomas.

  2. Neuronatin gene: Imprinted and misfolded: Studies in Lafora disease, diabetes and cancer may implicate NNAT-aggregates as a common downstream participant in neuronal loss.

  3. indicate that Nnat is related to keratinocyte differentiation by up-regulating involucrin (show IVL Proteins) expression

  4. methylation status of a not-yet-described regulatory element within the NNAT locus that contains four potential CTCF (show CTCF Proteins) binding sites determines the expression level of NNAT

  5. Neuronatin-mediated aberrant calcium signaling and endoplasmic reticulum stress underlie neuropathology in Lafora disease

  6. Neuronatin in a subset of glioblastoma multiforme tumor progenitor cells is associated with increased cell proliferation and shorter patient survival.

  7. A stringent analysis identified NNAT as a key imprinted gene that was dysregulated in induced pluripotent stem cells.

  8. malin (show NHLRC1 Proteins) negatively regulates neuronatin and its loss of function in Lafora disease results in increased accumulation of neuronatin

  9. A putative role of Nnat in human energy homeostasis is further emphasized by a consistent association between single nuc (show LEP Proteins)leotide polymorphisms (SNPs) in the human Nnat gene and severe childhood and adult obesity

  10. Hypermethylation of the imprinted NNAT locus occurs frequently in pediatric acute leukemia

Mouse (Murine) Neuronatin (NNAT) interaction partners

  1. Nnat expression in hypothalamus is regulated by short-term nutrient availability, but unaltered by diet-induced obesity or calorie restriction.

  2. Neuronatin appears to be a novel regulator of browning and metabolic substrate disposal in white adipocytes.

  3. the Neuronatin locus employs the most basic mechanism for establishing allele-specific gene expression

  4. Data show that Nnat initiates neural induction in ESCs through increasing intracellular Ca(2+) ([Ca(2+) ](i)) by antagonizing Ca(2+) -ATPase isoform 2 (sarco/endoplasmic reticulum Ca(2+) -ATPase isoform 2) in the endoplasmic reticulum.

  5. Nnat mRNA expression is decreased in several key appetite regulatory hypothalamic nuclei in rodents with impaired leptin (show LEP Proteins) signaling and during fasting conditions

  6. In the present study, we identified Nnat as a target gene of BETA2 in the pancreas.

  7. Western blot analysis of the mouse brain showed reduced levels of calpastatin and rabaptin-5 and higher amount of neuronatin in PKU compared to the wild type.

  8. Nnatalpha and Nnatbeta were primarily localized in the endoplasmic reticulum (ER), and their expressions increased insulin (show INS Proteins) secretion by increasing intracellular calcium levels.

Pig (Porcine) Neuronatin (NNAT) interaction partners

  1. Findings demonstrated important roles of NNAT in placenta function.

  2. Cloning and sequencing of cDNA from porcine anterior pituitary cDNA library, encoding alpha- and beta-neuronatin, cloned as gene expressed by fetal developing brain. Relative amounts of alpha to beta type reversed just after birth.

  3. polymorphism-based approach was used to detect the imprinting status of NNAT and DIRAS3 (show DIRAS3 Proteins) genes in five heterozygous pigs (based on SNP) of Large White and Meishan F(1) hybrids

Neuronatin (NNAT) Protein Profile

Protein Summary

The protein encoded by this gene is a proteolipid that may be involved in the regulation of ion channels during brain development. The encoded protein may also play a role in forming and maintaining the structure of the nervous system. This gene is found within an intron of the BLCAP gene, but on the opposite strand. This gene is imprinted and is expressed only from the paternal allele. Two transcript variants encoding two different isoforms have been found for this gene.

Gene names and symbols associated with Neuronatin Proteins (NNAT)

  • neuronatin (LOC100340901)
  • neuronatin (NNAT)
  • neuronatin (Nnat)
  • 5730414I02Rik protein
  • AW107673 protein
  • Peg5 protein

Protein level used designations for Neuronatin Proteins (NNAT)

neuronatin , neuronatin alpha , neuronatin isoform alpha

GENE ID SPECIES
100340901 Oryctolagus cuniculus
458231 Pan troglodytes
609195 Canis lupus familiaris
700562 Macaca mulatta
4826 Homo sapiens
18111 Mus musculus
94270 Rattus norvegicus
353114 Bos taurus
449004 Sus scrofa
101833100 Mesocricetus auratus
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