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NETO1 encodes a predicted transmembrane protein containing two extracellular CUB domains followed by a low-density lipoprotein class A (LDLa) domain. Additionally we are shipping NETO1 Antibodies (17) and NETO1 Kits (2) and many more products for this protein.
Showing 6 out of 9 products:
Human NETO1 Protein expressed in Human Cells - ABIN2004373
Stöhr, Berger, Fröhlich, Weber: A novel gene encoding a putative transmembrane protein with two extracellular CUB domains and a low-density lipoprotein class A module: isolation of alternatively spliced isoforms in retina and brain. in Gene 2002
Results suggested that the extracellular N-terminal region including the two CUB domains was largely responsible for the distinct regulatory effects of Neto1 and Neto2 (show NETO2 Proteins) on the desensitization properties of GluK1 (show GRIK1 Proteins) homomeric receptors
Neto1 is concluded to be a component of amyloid precursor protein (show APP Proteins) /NMDA receptor trafficking complexes
no evidence for the association of NETO1 with schizophrenia in the Japanese population
Mouse neto1 plays a critical role in spatial learning and memory through the regulation of NMDAR subunit abundance at synapses.
These results confirm that Neto protein interactions regulate synaptic localization of NMDA and kainate receptor subunits at mossy fiber-CA3 (show CA3 Proteins) pyramidal cell synapses.
This study demonistrated that Neto1 to regulate both NMDARs and KARs (show KARS Proteins) reveals a unique dual role in controlling synaptic transmission by serving as an auxiliary protein for these two classes of ionotropic glutamate (show GRIN1 Proteins) receptors in a synapse-specific fashion.
The results of this study indicated that two distinctive properties of native kainate receptors, their high-affinity binding pattern in the brain and slow kinetics at postsynapses, are conferred by the kainate receptors auxiliary subunit Neto1.
Assembly with NETO1 and NETO2 (show NETO2 Proteins) differentially modifies homomeric glutamate (show GRIN1 Proteins) K1 (GluK1 (show GRIK1 Proteins)) kainate receptor gating.
Data describe the isolation and characterization of a novel gene, Btcl1 (brain-specific (show CALY Proteins) transmembrane protein containing two CUB and an LDLa (show LDLR Proteins) domains), which has significant homology with neuropilin-1 (show NRP1 Proteins) and -2 in their CUB domains. [Btcl1]
Neto1 regulates NMDA receptor-dependent synaptic plasticity and cognition.
Focuses mainly on human NETO1 but also describes identification of mouse Neto1.
This gene encodes a predicted transmembrane protein containing two extracellular CUB domains followed by a low-density lipoprotein class A (LDLa) domain. A similar gene in mice encodes a protein that plays a critical role in spatial learning and memory by regulating the function of synaptic N-methyl-D-aspartic acid receptor complexes in the hippocampus. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1
, neuropilin and tolloid-like protein 1