anti-Neutrophil Cytosolic Factor 2 (NCF2) Antibodies

NCF2 encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. Additionally we are shipping NCF2 Proteins (12) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NCF2 4688 P19878
NCF2 17970 O70145
NCF2 364018 A7E3N2
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-NCF2 Antibodies at antibodies-online.com

Showing 10 out of 50 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-NCF2 Antibody Titration: 1.0 ug/ml Positive Control: MCF7 Whole Cell 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated IF, WB Western blot analysis of p67 [phox] on a EB1 cell lysate (Human B lymphoblast, Burkitt's lymphoma, ATCC HTB-60). Lane 1: 1:500, lane 2: 1:1000, lane 3: 1:2000 dilution of the mouse anti-p67 [phox] antibody. Immunofluorescence staining of C3H/10T1/2 cells (Mouse embryonic fibroblasts, ATCC CCL-226). 50 μg Log in to see 6 to 8 Days
$154.07
Details
Human Rabbit Un-conjugated IHC (p), WB Human Spleen, Neutrophils (formalin-fixed, paraffin-embedded) stained with NCF2 antibody ABIN305776 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 7 to 9 Days
$676.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunofluorescence: p67phox/NOXA2 Antibody [NBP1-82542] - Immunofluorescent staining of human cell line A-431 shows positivity in cytoplasm. Western Blot: p67phox/NOXA2 Antibody [NBP1-82542] - Lane 1: Marker [kDa] 229, 112, 84, 48, 32, 27, 17.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp.Lane 4: Human plasma (IgG/HSA depleted) 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Rabbit Un-conjugated IC, IF, IP, IHC, WB Immunofluorescent analysis of p67 phox staining in Hela cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibo Immunohistochemical analysis of p67 phox staining in mouse heart formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with th 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated ICC, IHC, IP, WB 100 μg Log in to see 15 to 18 Days
$314.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IP, WB Immunohistochemistry of paraffin-embedded mouse heart using NCF2 antibody at dilution of 1:100 (400x lens). 100 μL Log in to see 16 Days
$323.13
Details
Mouse Rabbit Un-conjugated IHC, WB Immunofluorescence analysis of HeLa cell using NCF2 antibody. Blue: DAPI for nuclear staining. 100 μL Log in to see 13 to 14 Days
$302.50
Details
Mouse Rabbit Un-conjugated ICC, IHC, IP, WB 100 μg Log in to see 13 to 16 Days
$324.00
Details

NCF2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,
, ,
,
, , , , , , , , , , , , ,
Mouse (Murine) ,
,
,
, , , , , , , , , , , , ,
Rat (Rattus) ,


, , , , , , , , , , , , ,

Top referenced anti-NCF2 Antibodies

  1. Human Monoclonal NCF2 Primary Antibody for IF, WB - ABIN968245 : Ago, Nunoi, Ito, Sumimoto: Mechanism for phosphorylation-induced activation of the phagocyte NADPH oxidase protein p47(phox). Triple replacement of serines 303, 304, and 328 with aspartates disrupts the SH3 domain-mediated intramolecular interaction in p47(phox), thereby activating in The Journal of biological chemistry 1999 (PubMed)
    Show all 5 Pubmed References

  2. Human Monoclonal NCF2 Primary Antibody for IF, WB - ABIN968246 : Benna, Dang, Gaudry, Fay, Morel, Hakim, Gougerot-Pocidalo: Phosphorylation of the respiratory burst oxidase subunit p67(phox) during human neutrophil activation. Regulation by protein kinase C-dependent and independent pathways. in The Journal of biological chemistry 1997 (PubMed)
    Show all 5 Pubmed References

  3. Human Polyclonal NCF2 Primary Antibody for ICC, IF - ABIN4343179 : Lomnytska, Becker, Bodin, Olsson, Hellman, Hellström, Mints, Hellman, Auer, Andersson: Differential expression of ANXA6, HSP27, PRDX2, NCF2, and TPM4 during uterine cervix carcinogenesis: diagnostic and prognostic value. in British journal of cancer 2011 (PubMed)

More Antibodies against NCF2 Interaction Partners

Pig (Porcine) Neutrophil Cytosolic Factor 2 (NCF2) interaction partners

  1. analysis of NCF2, BCKDHB (show BCKDHB Antibodies) and BCKDHA (show BCKDHA Antibodies) in pig

Human Neutrophil Cytosolic Factor 2 (NCF2) interaction partners

  1. Phosphoinositol 3-phosphate regulates reactive oxygen species production by maintaining p40phox (show NCF4 Antibodies) and p67phox at the phagosomal membrane.

  2. TLR4 (show TLR4 Antibodies)- and TLR2 (show TLR2 Antibodies)-induced IRAK (show IRAK1 Antibodies)-ERK (show EPHB2 Antibodies) pathway cross-talks with p67phox-Nox-2 (show CYBB Antibodies) for reactive oxygen species generation, thus regulating IL-1beta (show IL1B Antibodies) transcription and processing in monocytic cells.

  3. Skeletal muscle protein expression of the NADPH oxidase (show NOX1 Antibodies) subunits p22(phox (show CYBA Antibodies)), p47(phox), and p67(phox) was increased in obese relative to lean subjects, where p22(phox (show CYBA Antibodies)) and p67(phox) expression was attenuated by exercise training in obese subjects.

  4. A novel homozygous mutation in NCF2.

  5. results reveal an essential role for the Cys (show DNAJC5 Antibodies)-Gly-Cys (show DNAJC5 Antibodies) triad in Nox2 (show CYBB Antibodies) in binding p67(phox), seconded by an additional binding region, comprising residues C terminal to Cys (show DNAJC5 Antibodies)-Gly-Cys (show DNAJC5 Antibodies). The 2 regions interact with distinct partner sites in p67(phox).

  6. This model assigns a central role to Arg-395 in the structure and stability of the quaternary NCF2/NCF4 (show NCF4 Antibodies)/VAV1 (show VAV1 Antibodies)/RAC1 NADPH oxidase (show NOX1 Antibodies) complex.

  7. Data indicate that arachidonic acid induces the direct interaction of Rac (show AKT1 Antibodies)-GTP (show AK3 Antibodies)-bound p67(phox) with the C-terminal cytosolic region of phagocyte NADPH oxidase (show NOX1 Antibodies) Nox2 (show CYBB Antibodies).

  8. Four novel mutations in the NCF1 (show NCF1 Antibodies), NCF2, and CYBB (show CYBB Antibodies) genees have been identified in chronic granulomatous disease patients in Morocco.

  9. Results not only establish allelic heterogeneity within NCF2 associated with SLE, but also emphasize the utility of multi-ethnic cohorts to identify predisposing variants explaining additional phenotypic variance of complex diseases like SLE.

  10. NCF2 in Asian populations shows a pattern of diversity characterized by a differentiated haplotype structure.

Mouse (Murine) Neutrophil Cytosolic Factor 2 (NCF2) interaction partners

  1. Just as patients with chronic granulomatous disease who lack NADPH oxidase (show NOX1 Antibodies) rarely develop SLE, NCF-2-null mice on a nonautoimmune background were susceptible to a chronic granulomatous disease-like opportunistic infection but did not develop lupus. In contrast, on a lupus-prone background, even haploinsufficiency of NCF-2 accelerated the development of full-blown lupus disease.

  2. p67(phox) binds to phosphoPrdx6 and inhibits its PLA2 (show PLA2G2A Antibodies) activity, an interaction that could function to terminate the PLA2 (show PLA2G2A Antibodies)-mediated NOX2 (show CYBB Antibodies) activation signal.

  3. The results of this study suggested that repeated stress promotes depressive behavior through the upregulation of NADPH (show FDXR Antibodies) oxidasesubunit (67kDa (show RPSA Antibodies)) and the resultant metabolic oxidative stress.

  4. Data suggest that a cytosolic source of reactive oxygen species, probably p67(phox) subunit of cardiac NADPH oxidase 2 (NOX2 (show CYBB Antibodies)), may contribute to the hypertrophic phenotype in glucose transporter 4 gene (GLUT4 (show SLC2A4 Antibodies)-/-) mice.

  5. This report evaluates neutrophil cytosolic factor 2 (Ncf2) as a candidate Salmonella susceptibility gene for Ity3.

  6. This study demonstrates the involvement of ROS (show ROS1 Antibodies) from NADPH oxidase (show NOX1 Antibodies) in mediating paraquat cytotoxicity in BV-2 microglial cells and this process is mediated through PKCdelta (show PKCd Antibodies)- and ERK (show EPHB2 Antibodies)-dependent pathways.

NCF2 Antigen Profile

Protein Summary

This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene names and symbols associated with NCF2

  • neutrophil cytosolic factor 2 (NCF2) antibody
  • neutrophil cytosolic factor 2 (ncf2) antibody
  • neutrophil cytosolic factor 2 (p67phox) antibody
  • neutrophil cytosol factor 2 (VDBG_06643) antibody
  • neutrophil cytosolic factor 2 (PGTG_05816) antibody
  • neutrophil cytosolic factor 2 (LOC100136240) antibody
  • neutrophil cytosolic factor 2 (Ncf2) antibody
  • MGC81877 antibody
  • Ncf-2 antibody
  • NOXA2 antibody
  • P67-PHOX antibody
  • P67PHOX antibody
  • zgc:158405 antibody

Protein level used designations for NCF2

neutrophil cytosolic factor 2 (65kDa, chronic granulomatous disease, autosomal 2) , neutrophil cytosolic factor 2 , neutrophil cytosol factor 2 , predicted neutrophil cytosolic factor 2 , p67phox , p67-phox , NADPH oxidase cytosolic protein p67phox , NADPH oxidase cytosolic protein , 67 kDa neutrophil oxidase factor , NADPH oxidase activator 2 , chronic granulomatous disease, autosomal 2 , neutrophil NADPH oxidase factor 2 , neutrophil cytosolic factor 2 (65kD, chronic granulomatous disease, autosomal 2) , NADPH oxidase subunit (67 kD) , NADPH oxidase subunit (67kDa) , NCF-2

GENE ID SPECIES
424445 Gallus gallus
444487 Xenopus laevis
457573 Pan troglodytes
480036 Canis lupus familiaris
562473 Danio rerio
619224 Ciona intestinalis
619367 Xenopus (Silurana) tropicalis
9537124 Verticillium alfalfae VaMs.102
10531323 Puccinia graminis f. sp. tritici CRL 75-36-700-3
100008802 Oryctolagus cuniculus
100136240 Oncorhynchus mykiss
100142665 Sus scrofa
100174692 Pongo abelii
100270811 Salmo salar
4688 Homo sapiens
17970 Mus musculus
364018 Rattus norvegicus
281346 Bos taurus
Selected quality suppliers for anti-NCF2 (NCF2) Antibodies
Did you look for something else?