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Nitric Oxide Synthase 1, Neuronal Proteins (NOS1)

The protein encoded by NOS1 belongs to the family of nitric oxide synthases, which synthesize nitric oxide from L-arginine. Additionally we are shipping NOS1 Antibodies (285) and NOS1 Kits (48) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NOS1 4842 P29475
NOS1 24598 P29476
NOS1 18125 Q9Z0J4
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Top NOS1 Proteins at antibodies-online.com

Showing 10 out of 21 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$792.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 11 to 13 Days
$795.30
Details
HOST_Escherichia coli (E. coli) Rat His tag 100 μg Log in to see 11 to 13 Days
$827.20
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Sheep His tag   1 mg Log in to see 56 to 66 Days
$2,442.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$967.75
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 9 to 19 Days
$967.75
Details
HOST_Escherichia coli (E. coli) Rat Un-conjugated   100 μg Log in to see 9 to 19 Days
$999.22
Details

NOS1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Rat (Rattus)

Mouse (Murine)

More Proteins for Nitric Oxide Synthase 1, Neuronal (NOS1) Interaction Partners

Zebrafish Nitric Oxide Synthase 1, Neuronal (NOS1) interaction partners

  1. the dynamics of glial cell line-derived neurotrophic factor (gdnf (show GDNF Proteins)) and nitric oxide synthases (nos) mRNA expression in various regions of zebrafish brain

  2. NOS1 is a key regulator of motor axon ontogeny in the developing vertebrate spinal cord.

  3. The distribution pattern of nNOS gene expression showed the highest expression levels in the forebrain followed by the optic tectum, the brainstem and the spinal cord, whereas scarce expression was detected in the cerebellum.

Human Nitric Oxide Synthase 1, Neuronal (NOS1) interaction partners

  1. CoCl2 increased nNOS expression and NO production in human neuroblastoma (show ARHGEF16 Proteins) SK-N-SH cells by increasing HIF-1a (show HIF1A Proteins) expression and binding to a a hypoxia response element in the nNos promoter.

  2. DLC1 (show DYNLL1 Proteins) binding to nNOS-calmodulin (show CALM1 Proteins) complex does not affect the electron transport from the reductase to the oxygenase domain.

  3. We conclude that DNM2 (show DNM2 Proteins) is a novel negative regulator of NO production in mouse collecting ducts.

  4. analysis of the interaction between nNOS and dystrophin (show DMD Proteins) repeats 16 and 17

  5. This study first-time showed highest Red Blood Cell (RBC (show CACNA1C Proteins))-Nitric Oxide Synthase activation and nitric oxide production in old RBC (show CACNA1C Proteins).

  6. Results suggested a link between NOS1 gene polymorphism at rs3782206 and cognitive functions and their neural underpinnings at the right inferior frontal gyrus

  7. Tetrahydrobiopterin:dihydrobiopterin ratio is lower in tumor tissues and, as a consequence, NOS activity generates more peroxynitrite and superoxide anion than nitric oxide, resulting in important tumor growth-promoting and antiapoptotic signaling properties.

  8. Study found no significant differences either in the frequencies of the NOS1 rs7977109 and rs693534 genotypes or in the frequencies of the allelic variants of these SNPs in restless legs syndrome patients when compared with healthy controls

  9. Single nucleotide polymorphisms in nNOS, renalase (show RNLS Proteins), MTHFR (show MTHFR Proteins), CELSR1 and XYLB (show XYLB Proteins) genes were found significantly associated with ischemic stroke in Chinese patients.

  10. Studied and determined the localisation of neuronal NOS (nNOS) in human airway epithelium.

Cow (Bovine) Nitric Oxide Synthase 1, Neuronal (NOS1) interaction partners

  1. glutamate (show GRIN2A Proteins)-induced apoptosis was strongly reversed by nNOS inhibitors and weakly by iNOS (show NOS2 Proteins) inhibitors, thus indicating nNOS involvement in glutamate (show GRIN2A Proteins)-mediated apoptosis.

  2. The expression, localization, and distribution of 3 nitric oxide synthase enzymes through the estrous cycle in bovien fallopian tubes are reported.

  3. Lys842 in neuronal nitric-oxide synthase enables the autoinhibitory insert to antagonize calmodulin (show KRIT1 Proteins) binding, increase FMN (show FMN1 Proteins) shielding, and suppress interflavin electron transfer

Rabbit Nitric Oxide Synthase 1, Neuronal (NOS1) interaction partners

  1. findings indicate that spinal transection affects nNOS and parvalbumin (show PVALB Proteins) in different neuronal circuits

  2. amyloid and oxidative stress-related disease proteins like NOS 1 is increased in expression and form localized accumulations in diabetic muscle in this rabbit model of diabetes.

  3. Motoneurons in the ventral horns respond more sensitively to ischemia/reperfusion than do neurons localized in the other spinal cord regions. Changes in cNOS (show NOS3 Proteins) activity may also influence the axonal conductance in the white matter.

  4. Distribution pattern of the enzyme responsible for the synthesis of NO, nitric oxide synthase, in the population of primary afferent neurons of the trigeminal ganglion and mesencephalic trigeminal nucleus of the rabbit.

  5. The regional distribution of nitric oxide synthase activity and neuronal nitric oxide synthase immunoreactivity, measured segment by segment shows that nitric oxide may play a significant role in the stepping cycle in the quadrupeds.

  6. NOS via Nitric oxide production may play a neuroprotective role in ischemic/reperfusion injury.

Guinea Pig Nitric Oxide Synthase 1, Neuronal (NOS1) interaction partners

  1. form-deprivation myopia upregulates the expression of NMDAR1 (show GRIN1 Proteins) and ncNOS and increases cGMP content in the retina. NMDAR1 (show GRIN1 Proteins)/NO-cGMP pathway may contribute to abnormal visual signals during myopic progression.

Pig (Porcine) Nitric Oxide Synthase 1, Neuronal (NOS1) interaction partners

  1. This study demonstrated for the first time a strong expression of NGF, TrkA, CGRP, nNOS and neuronal specific enolase in the majority of esophageal enteric nervous system components.

  2. Our results suggest that the presence of low mycotoxin doses in feed slows down the mRNA expression of nitric oxide synthase-1 and nitric oxide synthase-2 genes which probably lowers the concentrations of nitric oxide, a common precursor of inflammation.

  3. nNOS is an important regulator of renal hemodynamics in the newborn kidney, but not in the adult.

  4. Data suggest that pig sperm contain bNOS, iNOS (show NOS2 Proteins), and eNOS (show NOS3 Proteins); up-regulation of NOS by leptin (show LEP Proteins) during acrosome reaction and inhibition of acrosome reaction by inhibitors of nitric oxide synthases suggests these enzymes are involved in acrosome reaction.

  5. Periodic acceleration (pGz) acutely increases endothelial and neuronal nitric oxide synthase expression in endomyocardium of normal swine.

  6. Regional difference in blood flow has no effect on nNOS protein content in different sized conduit arteries.

  7. study concludes that in the cerebral cortex of newborn piglets, the mechanism of hypoxia-induced increased tyrosine phosphorylation of nNOS is mediated by nNOS-derived nitric oxide.

  8. Data suggest that angiotensin II regulates nNOS and eNOS expression and NOS activity in afferent arterioles of the developing kidney via angiotensin 1 and 2 receptors.

Mouse (Murine) Nitric Oxide Synthase 1, Neuronal (NOS1) interaction partners

  1. 14. These findings indicated that an upregulation of nNOS and iNOS (show NOS2 Proteins) in the spinal cord is associated with bone cancer pain and suggests that exogenously administered L-NMMA may have beneficial effects to alleviate bone cancer pain.

  2. Results suggest a new role of neuronal nitric-oxide synthase at the intercalated discs for the cGMP-dependent nitric oxide pathway and the maintenance of intercalated discs morphology.

  3. Studied the specific role of NOS1 in the striatum in situations of nicotine sensitization and stress

  4. A fundamental role for NOS1-derived nitric oxide in regulating TLR4 (show TLR4 Proteins)-mediated inflammatory gene transcription.NOS1-derived nitric oxide promotes NF-kappaB (show NFKB1 Proteins) transcriptional activity through inhibition of Socs1 (show SOCS1 Proteins).

  5. Data indicate that neuronal nitric oxide synthase (nNOS) is a key molecule for pathogenesis of N-methyl-N-nitrosourea (MNU)-induced photoreceptor cell death.

  6. Data show that the number of S-nitrosocysteine sites was significantly reduced in the brains lacking endothelial nitric oxide synthase (eNOS (show NOS3 Proteins)(-/-)) or neuronal nitric oxide synthase (nNOS(-/-)).

  7. Homer1a (show HOMER1 Proteins) may be a key neuroprotective endogenous molecule that protects against NMDA-induced neuronal injury by disassembling NR2B (show GRIN2B Proteins)-PSD95 (show DLG4 Proteins)-nNOS complexes and reducing the membrane distribution of NR2B (show GRIN2B Proteins).

  8. We conclude that age-dependently upregulated NOS1 induces NADPH (show FDXR Proteins) oxidases

  9. Data indicate that a reduced mitochondrial connexin 43 (Cx43 (show GJA1 Proteins)) content is associated with a switch of the mitochondrial nitric oxide synthases iNOS (show NOS2 Proteins) and nNOS isoform and the respective mitochondrial rate of nitric oxide formation.

  10. Nitric oxide synthase deficiency has differential effects on ADAM12 (show ADAM12 Proteins) expression in growing mouse brain.

NOS1 Protein Profile

Protein Summary

The protein encoded by this gene belongs to the family of nitric oxide synthases, which synthesize nitric oxide from L-arginine. Nitric oxide is a reactive free radical, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities. In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter, and has been implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. This protein is ubiquitously expressed, with high level of expression in skeletal muscle. Multiple transcript variants that differ in the 5' UTR have been described for this gene but the full-length nature of these transcripts is not known. Additionally, alternatively spliced transcript variants encoding different isoforms (some testis-specific) have been found for this gene.

Gene names and symbols associated with NOS1

  • nitric oxide synthase 1 (neuronal) (nos1)
  • nitric oxide synthase 1 (neuronal) (NOS1)
  • nitric oxide synthase (NNOS)
  • nitric oxide synthase 1 (neuronal) (Nos1)
  • nitric oxide synthase 1, neuronal (Nos1)
  • 2310005C01Rik protein
  • bNOS protein
  • IHPS1 protein
  • N-NOS protein
  • NC-NOS protein
  • nNOS protein
  • NO protein
  • NOS protein
  • Nos-1 protein
  • NOS-I protein
  • NOS1 protein

Protein level used designations for NOS1

nitric oxide synthase, brain , nitric oxide synthase 1 (neuronal) , Nitric oxide synthase, brain , NOS type I , constitutive NOS , neuronal NOS , peptidyl-cysteine S-nitrosylase NOS1 , N-NOS , NC-NOS , bNOS , nNOS , neuronal nitric oxide synthase , nitric oxidase synthase

GENE ID SPECIES
60658 Danio rerio
467139 Pan troglodytes
100597250 Nomascus leucogenys
443533 Ovis aries
4842 Homo sapiens
536132 Bos taurus
100009243 Oryctolagus cuniculus
100729682 Cavia porcellus
477498 Canis lupus familiaris
100520934 Sus scrofa
427721 Gallus gallus
101100342 Felis catus
24598 Rattus norvegicus
18125 Mus musculus
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