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Nuclear Factor, Interleukin 3 Regulated Proteins (NFIL3)

Expression of interleukin-3 (IL3\; MIM 147740) is restricted to activated T cells, natural killer (NK) cells, and mast cell lines. Additionally we are shipping NFIL3 Antibodies (88) and NFIL3 Kits (30) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NFIL3 4783 Q16649
Rat NFIL3 NFIL3 114519 Q6IMZ0
NFIL3 18030 O08750
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Top NFIL3 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$3,287.17
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$3,300.00
Details

NFIL3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

Top referenced NFIL3 Proteins

  1. Human NFIL3 Protein expressed in Wheat germ - ABIN1312476 : Ohno, Onishi, Ishida: A novel E4BP4 element drives circadian expression of mPeriod2. in Nucleic acids research 2007 (PubMed)

More Proteins for Nuclear Factor, Interleukin 3 Regulated (NFIL3) Interaction Partners

Human Nuclear Factor, Interleukin 3 Regulated (NFIL3) interaction partners

  1. E4BP4 and BIM (show BCL2L11 Proteins) regulation correlated with that of RCAN1 (show RCAN1 Proteins)-1. A putative GRE and four EBPREs were identified within 1500bp upstream from the transcription start site of RCAN1 (show RCAN1 Proteins)-1

  2. Results conclude that the transcriptional repressor E4BP4 plays a role in repressing epigenetically regulated SOSTDC1 (show SOSTDC1 Proteins) expression in breast cancer cells, which can be reverted by E4BP4 silencing.

  3. NFIL3 plays a neuroprotective role in neurons and constitutes a potential therapeutic target for neurodegeneration.

  4. Data indicate that E4BP4 can inhibit CD40L (show CD40LG Proteins) expression through epigenetic modifications in the promoter region of CD40L (show CD40LG Proteins).

  5. NFIL3 alters cancer cell behavior and FOXO (show FOXO3 Proteins) function by acting on chromatin to restrict the menu of FOXO (show FOXO3 Proteins) target genes

  6. The clock-regulated and immune system modulator transcription factor E4BP4/ NFIL3 likely regulates the expression of both appb in zebrafish and APP (show APP Proteins) in humans.

  7. G9a (show EHMT2 Proteins) mediates E4BP4-dependent suppression of hepatic Fgf21 (show FGF21 Proteins) by enhancing histone methylation (H3K9me2) of the Fgf21 (show FGF21 Proteins) promoter

  8. Conclude that E4BP4 plays as a survival factor in heart and E4BP4 is essential for proper embryonic heart development.

  9. This report demonstrates that GC-mediated upregulation of the bZIP transcriptional repressor gene, E4BP4, is dependent on [Ca2 (show CA2 Proteins)+]i levels, and correlates with GC-evoked apoptosis of GC-sensitive CEM-C7-14 cells.

  10. E4BP4 has a role as osteoblast transcriptional repressor in inhibiting both Runx2 (show RUNX2 Proteins) and Osterix (show SP7 Proteins) in myeloma bone disease

Zebrafish Nuclear Factor, Interleukin 3 Regulated (NFIL3) interaction partners

  1. Study shows that Nfil3 is enriched in the myeloid compartment of adult zebrafish including eosinophils.

  2. conclude that E4BP4/NIFL3 plays as a survival factor in heart and E4BP4 is essential for proper embryonic heart development.

Mouse (Murine) Nuclear Factor, Interleukin 3 Regulated (NFIL3) interaction partners

  1. removal of NFIL3 in vivo does not recapitulate the regeneration-promoting effects that were previously observed in vitro.

  2. These findings establish that NFIL3 directs the differentiation of a committed innate lymphoid cell precursor.

  3. These data identify an IL-27 (show IL27 Proteins)/NFIL3 signalling axis as a key regulator of effector T-cell responses via induction of Tim-3 (show HAVCR2 Proteins), IL-10 (show IL10 Proteins) and T-cell dysfunction.

  4. establish NFIL3 as a key regulator of common helper-like innate lymphoid cells progenitors as they emerge during early lymphopoiesis

  5. Iso-mediated induction of Nfil3 in osteoblasts regulates the expression of Ptgs2 (show PTGS2 Proteins) by driving the expression of circadian clock genes

  6. E4BP4 plays a crucial role in glucocorticoid -evoked apoptosis of osteoblasts by enabling induction of Bim (show BCL2L11 Proteins)

  7. Nfil3 is a key regulator of the development of innate lymphoid cell subsets essential for immune protection in the lung and gut (show GUSB Proteins).

  8. Nfil3 is critical for normal development of gut (show GUSB Proteins)-associated type 3 innate lymphoid cells. Nfil3 deficiency severely compromises intestinal innate immune defense against acute bacterial infection with Citrobacter rodentium and Clostridium difficile.

  9. signals transmitted by Ly49H and proinflammatory cytokines are sufficient to promote NK cell differentiation in the absence of Nfil3.

  10. E4bp4 is required for commitment to the natural killer (NK) lineage and promotes NK development by directly regulating the expression of the downstream transcription factors Eomes and Id2.

NFIL3 Protein Profile

Protein Summary

Expression of interleukin-3 (IL3\; MIM 147740) is restricted to activated T cells, natural killer (NK) cells, and mast cell lines. Transcription initiation depends on the activating capacity of specific protein factors, such as NFIL3, that bind to regulatory regions of the gene, usually upstream of the transcription start site (Zhang et al., 1995

Gene names and symbols associated with NFIL3

  • nuclear factor, interleukin 3 regulated (nfil3)
  • nuclear factor, interleukin 3 regulated (NFIL3)
  • nuclear factor, interleukin 3 regulated (Nfil3)
  • nuclear factor, interleukin 3, regulated (Nfil3)
  • nuclear factor, interleukin 3, regulated-like (LOC100345297)
  • AV225605 protein
  • E4BP4 protein
  • E4BP4-1 protein
  • IL3BP1 protein
  • MGC107826 protein
  • NF-IL3A protein
  • NFIL3 protein
  • NFIL3A protein
  • zgc:100867 protein

Protein level used designations for NFIL3

nuclear factor, interleukin 3 regulated , nuclear factor interleukin-3-regulated protein-like , E4 promoter-binding protein 4 , interleukin-3 promoter transcriptional activator , interleukin-3-binding protein 1 , nuclear factor interleukin 3 regulated protein , nuclear factor interleukin-3-regulated protein , transcriptional activator NF-IL3A , E4 promoter binding-protein 4 , E4 binding protein 4-1 , E4BP4 , ze4bp4-1 , bZIP protein E4BP4 , cE4BP4 protein , embryo implantation-related NFIL3/E4BP4-like transcription factor

GENE ID SPECIES
548427 Xenopus (Silurana) tropicalis
704757 Macaca mulatta
100395886 Callithrix jacchus
100440595 Pongo abelii
742792 Pan troglodytes
100554409 Anolis carolinensis
100587135 Nomascus leucogenys
4783 Homo sapiens
476347 Canis lupus familiaris
506097 Bos taurus
114519 Rattus norvegicus
445509 Danio rerio
447503 Xenopus laevis
395326 Gallus gallus
100726742 Cavia porcellus
100153822 Sus scrofa
100217409 Ovis aries
18030 Mus musculus
100345297 Oryctolagus cuniculus
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