anti-ORM1-Like 3 (S. Cerevisiae) (ORMDL3) Antibodies

Negative regulator of sphingolipid synthesis. Additionally we are shipping ORMDL3 Proteins (4) and ORMDL3 Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ORMDL3 94103 Q8N138
ORMDL3 66612 Q9CPZ6
ORMDL3 360618 Q6QI25
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Top anti-ORMDL3 Antibodies at antibodies-online.com

Showing 10 out of 24 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB ORMDL3 Antibody (Center) (ABIN654696) western blot analysis in mouse testis tissue lysates (35 µg/lane). This demonstrates the ORMDL3 antibody detected the ORMDL3 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of ORMDL3 Antibody (Center) in mouse testis tissue lysates (35ug/lane). This demonstrates the ORMDL3 antibody detected the ORMDL3 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB Western Blot: ORMDL3 Antibody [NBP1-98511] - Jurkat Cell Lysate 1.0ug/ml, Gel Concentration: 10-20% 100 μL Log in to see 8 to 11 Days
$447.56
Details
Human Rabbit Un-conjugated IHC (p), WB Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) 200 μL Log in to see 7 to 9 Days
$451.00
Details
Bat Rabbit Un-conjugated WB   50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated WB Western Blot at 1:1000 dilution Lane 1: Jurkat whole cell lysate Lane 2: mouse testis lysate Lysates/proteins at 20 ug per lane. 400 μL Log in to see 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated ELISA, WB   200 μL Log in to see 7 to 9 Days
$793.83
Details
Human Rabbit APC ELISA, WB   200 μL Log in to see 7 to 9 Days
$1,013.83
Details
Human Rabbit HRP ELISA, WB   200 μL Log in to see 7 to 9 Days
$1,013.83
Details

ORMDL3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human


, , , , ,
Mouse (Murine)


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Rat (Rattus)


Top referenced anti-ORMDL3 Antibodies

  1. Human Polyclonal ORMDL3 Primary Antibody for WB - ABIN654696 : Fransen, Visschedijk, van Sommeren, Fu, Franke, Festen, Stokkers, van Bodegraven, Crusius, Hommes, Zanen, de Jong, Wijmenga, van Diemen, Weersma: Analysis of SNPs with an effect on gene expression identifies UBE2L3 and BCL3 as potential new risk genes for Crohn's disease. in Human molecular genetics 2010 (PubMed)
    Show all 6 Pubmed References

More Antibodies against ORMDL3 Interaction Partners

Human ORM1-Like 3 (S. Cerevisiae) (ORMDL3) interaction partners

  1. These studies suggest that increased levels of ORMDL3 contribute to antiviral defense to rhinovirus infection in mice (hORMDL3(zp3 (show ZP3 Antibodies)-Cre) mice which have universal increased expression of human ORMDL3) through pathways that may include IFNs (IFN-alpha (show IFNA Antibodies), IFN-beta (show IFNB1 Antibodies), IFN-lambda), OAS (show SMOC1 Antibodies), and RNAse L (show RNASEL Antibodies).

  2. this study demonstrated the upregulation of (show ATF6 Antibodies) ORMDL3 (show BECN1 Antibodies)in patients with systemic lupus erythematosus

  3. ORMDL3 might influence de novo sphingolipid metabolism downstream of serine palmitoyltransferase

  4. modest changes (8-13%) in promoter methylation levels of ZPBP2 (show ZPBP2 Antibodies) and GSDMA (show GSDMA Antibodies) may cause substantial changes in RNA levels and allelic expression of ZPBP2 (show ZPBP2 Antibodies) and ORMDL3 is mediated by DNA methylation (show HELLS Antibodies)

  5. Decreased ORMDL3 expression increased levels of free sphingoid bases and sphingoid base phosphates, and also caused increases in cellular levels of ceramides.

  6. ORMDL3 overexpression is associated with asthma.

  7. The TT homozygote and the T allele of rs7216389 in ORMDL3 increased bronchiolitis risk. The rs7216389 polymorphism may be a predictor for identifying infants with predisposition to virus-induced wheezing to persistent asthma.

  8. Two single nucleotide polymorphisms regulating ORMDL3 expression (rs7216389 and rs9303277) significantly associated with atherosclerosis risk and the evidence of increased ORMDL3 expression in AS cases compared to controls.

  9. The SNP (rs7216389) of ORMDL3 does not influence the expression of OPN (show SPP1 Antibodies) and TGF-beta1 (show TGFB1 Antibodies), suggesting that it may not be associated with airway remodeling.

  10. ORMDL3 variants have been shown to be associated with Asthma in children with Rhinovirus infections -induced wheezing illnesses.

Mouse (Murine) ORM1-Like 3 (S. Cerevisiae) (ORMDL3) interaction partners

  1. ORMDL3 mediates the autophagy via the ATF 6 (show ATF6 Antibodies)-Beclin1 (show BECN1 Antibodies) autophagy pathway, and it facilitates the survival of splenic B cells via promoting autophagy and suppressing apoptosis

  2. ORMDL3 might influence de novo sphingolipid metabolism downstream of serine palmitoyltransferase

  3. inhibiting ORMDL3 in airway epithelial cells plays a significant role in induction of allergen-induced increases in airway hyperresponsiveness

  4. ORMDL3, an asthma susceptibility gene identified by genome-wide association studies, contributes to key pathways that promote changes in airway physiology during allergic immune responses.

  5. Mediated by GATA3 (show GATA3 Antibodies) through targeting promoter region of ORMDL3.

  6. Downregulation of ORMDL3 expression in mast cells enhances AKT (show AKT1 Antibodies) and NF-kappaB (show NFKB1 Antibodies)-directed signaling pathways and chemotaxis and contributes to the development of mast cell-mediated local inflammation in vivo.

  7. overexpression of ORMDL3 regulates ceramide homeostasis in cells in a complex manner and suggest that local FTY720 administration might be a useful therapeutic intervention for the control of allergic asthma.

  8. the contribution of ORMDL3 to asthma risk may involve changes in sphingolipid metabolism

  9. These studies provide evidence that ORMDL3 plays an important role in vivo in airway remodeling potentially through ATF6 (show ATF6 Antibodies) target genes.

  10. ORMDL3 promotes eosinophil trafficking and activation via regulation of CD18 (show ITGB2 Antibodies), CD49d, and CD48 (show CD48 Antibodies).

ORMDL3 Antigen Profile

Protein Summary

Negative regulator of sphingolipid synthesis. May indirectly regulate endoplasmic reticulum-mediated Ca(+2) signaling (By similarity).

Gene names and symbols associated with ORMDL3

  • ORM1-like 3 (S. cerevisiae) (ORMDL3) antibody
  • ORM1-like 3 (S. cerevisiae) (Ormdl3) antibody
  • 2810011N17Rik antibody
  • AI315223 antibody
  • LRRGT00183 antibody

Protein level used designations for ORMDL3

ORM1-like protein 3 , liver regeneration-related protein LRRGT00183

GENE ID SPECIES
94103 Homo sapiens
66612 Mus musculus
360618 Rattus norvegicus
615368 Bos taurus
100479284 Ailuropoda melanoleuca
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