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Transcription factor that plays a role in the regulation of embryonic heart and urogenital development (By similarity).. Additionally we are shipping OSR1 Proteins (8) and many more products for this protein.
Showing 10 out of 78 products:
Human Monoclonal OSR1 Primary Antibody for IF, IHC (p) - ABIN530633
Yang, Lo, Wu, Lin, Yeh, Chu, Sytwu, Uchida, Sasaki, Lin: SPAK-knockout mice manifest Gitelman syndrome and impaired vasoconstriction. in Journal of the American Society of Nephrology : JASN 2010
Show all 3 references for ABIN530633
Human Polyclonal OSR1 Primary Antibody for EIA - ABIN358502
Richardson, Rafiqi, Karlsson, Moleleki, Vandewalle, Campbell, Morrice, Alessi: Activation of the thiazide-sensitive Na+-Cl- cotransporter by the WNK-regulated kinases SPAK and OSR1. in Journal of cell science 2008
Show all 2 references for ABIN358502
Human Monoclonal OSR1 Primary Antibody for ELISA - ABIN566802
Takahashi, Mori, Nomura, Khan, Araki, Zeniya, Sohara, Rai, Sasaki, Uchida: WNK4 is the major WNK positively regulating NCC in the mouse kidney. in Bioscience reports 2014
Osr1/Osr2 normally repress bmp4 (show BMP4 Antibodies) expression in the lateral plate mesoderm prior to respiratory specification.
nephrogenic transcription factors (osr1, osr2, hnf1b (show HNF1B Antibodies), lhx1 (show LHX1 Antibodies), pax8 (show PAX8 Antibodies))play important role in nephrogenesis but have no pronephros induction potential upon overexpression; they activate transcription cascades reflecting activation by activin A (show INHBA Antibodies), retinoic acid
In summary, our study implicated a gene network involving Tbx5 (show TBX5 Antibodies), Osr1 (show OXSR1 Antibodies) and Pcsk6 (show PCSK6 Antibodies) interaction in second heart field for atrial septation, providing a molecular framework for understanding the role of Tbx5 (show TBX5 Antibodies) in congenital heart disease ontogeny.
SPAK (show STK39 Antibodies) and OSR1 (show OXSR1 Antibodies) are both stimulators of Kir2.1 (show KCNJ2 Antibodies) activity.
SPAK (show STK39 Antibodies) and OSR1 (show OXSR1 Antibodies) are powerful stimulators of the intestinal Na+-coupled phosphate co-transporter NaPi-IIb (show SLC34A2 Antibodies)
OSR1 (show OXSR1 Antibodies) protein has both the potential to up-regulate KCNQ1 (show KCNQ1 Antibodies)/E1 protein abundance in the cell membrane, an effect possibly participating in the regulation of cell volume, excitability, epithelial transport and metabolism.
SPAK (show STK39 Antibodies) and OSR1 (show OXSR1 Antibodies) are powerful negative regulators of the excitatory glutamate (show GRIN1 Antibodies) transporters EAAT1 (show SLC1A3 Antibodies) and EAAT2 (show SLC1A2 Antibodies).
SPAK (show STK39 Antibodies) and OSR1 (show OXSR1 Antibodies) are negative regulators of EAAT3 (show SLC1A1 Antibodies) activity
OSR1 (show OXSR1 Antibodies) has the capacity to downregulate the peptide transporters PEPT1 (show SLC15A1 Antibodies) and PEPT2 (show SLC15A2 Antibodies) by decreasing the carrier protein abundance in the cell membrane
Both, SPAK (show STK39 Antibodies) and OSR1 (show OXSR1 Antibodies), are negative regulators of the creatine transporter SLC6A8 (show SLC6A8 Antibodies)
SPAK (show STK39 Antibodies) and OSR1 (show OXSR1 Antibodies) are powerful negative regulators of the cell volume regulatory Cl- channel ClC-2 (show CLCN2 Antibodies)
The findings of the present study showed, for the first time, the role of the OSR1 (show OXSR1 Antibodies) rs12329305 polymorphism in the development of congenital malformations in cases of stillborn/neonatal death.
Tbx5 (show TBX5 Antibodies) and Osr1 interact to regulate posterior second heart field cell cycle progression for cardiac septation.
odd-skipped related 1 is involved in regulation of mammalian kidney development
ROMK1 (show KCNJ1 Antibodies) protein abundance and activity are down-regulated by SPAK (show STK39 Antibodies) and OSR1
study identifies a separation of functions for the WNK1 (show WNK1 Antibodies)-activated protein kinases OSR1 and SPAK (show STK39 Antibodies) in mediating proliferation, invasion, and gene expression in endothelial cells
WNK 1 (show WNK1 Antibodies), 3, 4, OSR1, and SPAK (show STK39 Antibodies) signaling system known to play a role in regulating the phosphorylation status, and hence activity of the CCCs in other tissues, is also present in the rat and human lenses.
Osr1 plays crucial roles in Six2 (show SIX2 Antibodies)-dependent maintenance of nephron progenitors during mammalian nephrogenesis.
Data indicate that Activin A (show INHBA Antibodies) and retinoic acid (RA) induced theto embryonic stem cells (mESCs) expression of marker genes and proteins for intermediate mesoderm, odd-skipped related 1 (Osr1) and Wilms Tumor 1 (Wt1 (show WT1 Antibodies)).
Odd-skipped related-1 controls neural crest chondrogenesis during tongue development.
OSR1 is expressed in proximal renal tubules and participates in the regulation of FGF23 (show FGF23 Antibodies) release and renal tubular phosphate transport.
WNK1 (show WNK1 Antibodies) activation of the OSR1 signaling cascade is an essential pathway that regulates angiogenesis and cardiac formation during mouse embryo development.
findings identify osr1 as a Nodal-induced, negative feedback regulator of Nodal signaling that acts at the earliest stages of endoderm differentiation to limit the number of endoderm progenitors.
Our results place osr1 in a framework of transcriptional regulators that control the expression of podocin and nephrin (show NPHS1 Antibodies) and thereby mediate podocyte differentiation.
The Osr1 and Osr2 genes act in the pronephric anlage downstream of retinoic acid signaling and upstream of Wnt2b (show WNT2B Antibodies) to maintain pectoral fin development.
osr1 reveals a novel role for endoderm in regulating kidney versus vascular cell fate.
Transcription factor that plays a role in the regulation of embryonic heart and urogenital development (By similarity).
odd-skipped related 1 (Drosophila)
, protein odd-skipped-related 1
, zinc finger transcription factor
, odd-skipped homolog
, oxidative-stress responsive 1