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Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis (By similarity).. Additionally we are shipping OIP5 Antibodies (18) and many more products for this protein.
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High OIP5 expression is associated with bladder cancer.
Mitofusin 2 (show MFN2 Proteins) knockdown altered Neisseria gonorrhoeae opacity-associated-interacting protein 5 (show CAPS Proteins) (OIP5) expression.
These findings suggest that OIP5 may be involved in hepatocellular carcinoma (HCC (show FAM126A Proteins)) growth and metastasis and that miR (show MLXIP Proteins)-15b-5p inhibits OIP5-mediated oncogenic signaling in HCC (show FAM126A Proteins).
the Mis18 complex contains dual CENP-C recognition motifs that are combinatorially required to generate robust centromeric localization that leads to CENP-A (show CENPA Proteins) deposition
OIP5 over-expression inhibited hsa (show CD24 Proteins)-miR (show MLXIP Proteins)-139-5p expression, antagonized its functions and led to the de-repression of its endogenous target NOTCH1 (show NOTCH1 Proteins), which was a core oncogene (show RAB1A Proteins) in promoting breast cancer progression.
Stable binding of Mis18alpha (show MIS18A Proteins)-Mis18beta heterotetramer to centromeres in telophase licenses them for CENP-A (show CENPA Proteins) deposition.
Over-expression of OIP5 was observed in breast tumors.
Mis18beta binds with and specifies the centromere localization of HJURP (show HJURP Proteins).
this study showed betaTrCP (show BTRC Proteins)-mediated regulation of Mis18beta stability is a mechanism to restrict centromere function of Mis18 complex from late mitosis to early G1 phase.
expression of AURKC (show AURKC Proteins), OIP5, PIWIL2 and TAF7L (show TAF7L Proteins) differed between patients with Acute myeloid leukemia (show BCL11A Proteins), myelodysplastic syndrome and healthy controls in a gender-dependent manner
Increase of Oip5 may associate with development of obesity.
Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis (By similarity).
, Opa interacting protein 5
, LAP2alpha interactor-25
, MIS18 kinetochore protein homolog B
, cancer/testis antigen 86
, opa-interacting protein 5
, opa-interacting protein 5 homolog