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Ornithine Decarboxylase Antizyme 1 Proteins (OAZ1)

Ornithine decarboxylase catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. Additionally we are shipping OAZ1 Antibodies (25) and OAZ1 Kits (8) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
OAZ1 4946 P54368
OAZ1 18245 P54369
OAZ1 25502 P54370
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Top OAZ1 Proteins at antibodies-online.com

Showing 10 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Yeast Zebrafish His tag   1 mg Log in to see 56 to 66 Days
$2,530.00
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$2,531.83
Details
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$2,531.83
Details
Yeast Mesocricetus auratus His tag   1 mg Log in to see 56 to 66 Days
$2,552.00
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,566.67
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,566.67
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 3 to 4 Days
$382.86
Details

OAZ1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human

Mouse (Murine)

Rat (Rattus)

Top referenced OAZ1 Proteins

  1. Human OAZ1 Protein expressed in Escherichia coli (E. coli) - ABIN1098382 : Aoto, Miyake, Nakamura, Tajima: Genomic organization of the mouse AZ1 gene that encodes the protein localized to preacrosomes of spermatids. in Genomics 1997 (PubMed)
    Show all 2 references for ABIN1098382

More Proteins for Ornithine Decarboxylase Antizyme 1 (OAZ1) Interaction Partners

Human Ornithine Decarboxylase Antizyme 1 (OAZ1) interaction partners

  1. Data show the the interplay between the enzyme ornithine decarboxylase (ODC) and two regulatory proteins: antizyme (Az) and inhibitor (AzIN).

  2. Results show that ornithine decarboxylase antizyme 1 (OAZ1) simultaneously inhibits the proliferation and induces the differentiation of oral cancer cells.

  3. To further understand its functions in CML (show BCR Proteins) pathogenesis, OAZ1 was overexpressed, and PCR array analysis was used to monitor the expression of key genes commonly involved in leukemia development.

  4. Gene expression studies have identified altered expression of ornithine decarboxylase antizyme 1 in suicide completers with a history of mood disorders.

  5. In the absence of amino acids, mTORC1 is inhibited, whereas mTORC2 (show CRTC2 Proteins) is activated, leading to the inhibition of global protein synthesis and increased AZ1 synthesis via a cap-independent mechanism.

  6. AZ_95-176 is the minimal AZ peptide that is fully functioning in the binding of ODC (show ODC1 Proteins) and AZI and inhibition of their function.

  7. the differences in residues 125 and 140 in ODC and AZI are responsible for the differential antizyme-binding affinities

  8. Data show that OAZ promotes the removal of Mps1 (show IDUA Proteins) from centrosomes, and centrosome overproduction caused by reducing OAZ activity requires Mps1 (show IDUA Proteins).

  9. These data together demonstrate the existence of a c-Jun (show JUN Proteins)-dependent mechanism regulating the abundance of the antiapoptotic DNp73 in response to genotoxic stress.

  10. Human AZI is capable of acting as a general inhibitor for all members of the antizyme family.

Mouse (Murine) Ornithine Decarboxylase Antizyme 1 (OAZ1) interaction partners

  1. Interaction of polyamines and mTOR signaling in the synthesis of antizyme (AZ).

  2. we have generated transgenic mice overexpressing mouse antizyme 1 gene under its own regulatory sequences

  3. Ornithine decarboxylase antizyme expression reduces tumor incidence, multiplicity and size even in the absence of p53 (show TP53 Proteins).

  4. The activity of AZ1 was low in the virgin and involuting stages, but increased markedly during late pregnancy and early lactation.

  5. These data together demonstrate the existence of a c-Jun (show JUN Proteins)-dependent mechanism regulating the abundance of the antiapoptotic DNp73 in response to genotoxic stress.

  6. Testosterone treatment enhanced AZ1 and N1-SSAT (show SAT1 Proteins) mRNA levels in a time-dependent manner

  7. antizyme and glycosaminoglycans have roles in polyamine transport

  8. OAZ can alter the intensity and duration of the BMP4 (show BMP4 Proteins) stimulus through Smad6 (show SMAD6 Proteins)

  9. Az-1 has a central and meaningful role in modulation of polyamine homeostasis, and in regulating cellular proliferation and transformation properties.

  10. The data-driven docking results suggest that both proteins occupy the same binding site on Az1, with Az1 binding within a large groove in antizyme inhibitor (AzI) and Ornithine Decarboxylase (ODC (show ODC1 Proteins)).

Xenopus laevis Ornithine Decarboxylase Antizyme 1 (OAZ1) interaction partners

  1. antizyme expression requires programmed,+1 ribosomal frameshifting

OAZ1 Protein Profile

Protein Summary

Ornithine decarboxylase catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. The ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. Antizyme expression is auto-regulated by polyamine-enhanced translational frameshifting. The antizyme encoded by this gene inhibits ornithine decarboxylase and accelerates its degradation.

Gene names and symbols associated with OAZ1

  • ornithine decarboxylase antizyme 1 (OAZ1)
  • ornithine decarboxylase antizyme 1 (Oaz1)
  • ornithine decarboxylase antizyme 1 (oaz1)
  • ornithine decarboxylase antizyme 1a (oaz1a)
  • Antizyme protein
  • AZ-1 protein
  • AZ1 protein
  • AZI protein
  • AZS protein
  • oaz protein
  • oaz1 protein
  • ODC-Az protein
  • ODCAC protein

Protein level used designations for OAZ1

ODC-Az , antizyme 1 , ODC antizyme , ODC-Az-S , ornithine decarboxylase antizyme 1

GENE ID SPECIES
4946 Homo sapiens
18245 Mus musculus
25502 Rattus norvegicus
506973 Bos taurus
395746 Gallus gallus
379737 Xenopus laevis
101826304 Mesocricetus auratus
259192 Danio rerio
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