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Oxysterols are byproducts of cholesterol that can have cytotoxic effects on many cell types. Additionally we are shipping OSBP2 Antibodies (40) and OSBP2 Kits (2) and many more products for this protein.
Showing 4 out of 4 products:
ORP4 promotes the survival of rapidly proliferating cells.
Inhibition of HCV replication by oxysterol-binding protein-related protein 4 (ORP4) through interaction with HCV NS5B and alteration of lipid droplet formation.
In preliminary results, significantly higher levels of OSBP2 and OSBPL-7 (show OSBPL7 Proteins) mRNA were seen in blood samples from cholangiocarcinoma patients than in healthy controls.
OSBP2 has a role in chronic myeloid leukemia (show BCL11A Proteins)
Thus the sterol-binding domain of ORP4 binds vimentin (show VIM Proteins), cholesterol and oxysterols, and interacts with the filamentous vimentin (show VIM Proteins) network.
a possible role of OSBP2 gene in the pathogenesis of oxidative damage to the macula induced by oxysterols in age-related macular degeneration patients.
ORP4 is essential for the postmeiotic differentiation of germ cells
Oxysterols are byproducts of cholesterol that can have cytotoxic effects on many cell types. The membrane-bound protein encoded by this gene contains a pleckstrin homology (PH) domain and an oxysterol-binding region. It binds oxysterols such as 7-ketocholesterol and may inhibit their cytotoxicity. Alternate transcriptional splice variants have been observed but have not been fully characterized.
oxysterol-binding protein 2
, OSBP-related protein 4
, oxysterol binding protein-like 1
, oxysterol binding protein-related protein 4
, oxysterol-binding protein-related protein 4