anti-P21-Activated Kinase 6 (PAK6) Antibodies

PAK6 encodes a member of the p21-activated kinase (PAK) family. Additionally we are shipping P21-Activated Kinase 6 Proteins (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PAK6 56924 Q9NQU5
PAK6 214230 Q3ULB5
PAK6 296078  
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Top anti-P21-Activated Kinase 6 Antibodies at antibodies-online.com

Showing 10 out of 166 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB Western blot analysis of anti-PAK6 Pab (ABIN392439) in lysates from transiently transfected COS7 cells. Lane 1: negative control, Lane 2: PAK1-expressing cells, Lane 3: PAK2-expressing cells, Lane 4: PAK4-expressing cells, Lane 5: PAK5-expressing cells, and Lane 6: PAK6-expressing cells. PAK6 (arrow) was detected using purified polyclonal antibody. Data is kindly provided by Drs. Z.M. Jaffer and J. Chernoff from the Fox Chase Cancer Center (Philadelphia, PA). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IF, IHC (p), WB PAK6 Antibody (Center)  western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the PAK6 antibody detected the PAK6 protein (arrow). PAK6 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PAK6 Antibody (Center) for immunohistochemistry.  Clinical relevance has not been evaluated. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IP, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: PAK6 Antibody [NBP1-76632] - Raji cells with PAK6 antibody at 10 ug/ml. Immunocytochemistry/Immunofluorescence: PAK6 Antibody [NBP1-76632] - Immunofluorescence of PAK6 in Raji cells with PAK6 antibody at 10 ug/mL. 0.1 mg Log in to see 8 to 11 Days
$447.56
Details
Human Rabbit Un-conjugated WB Western blot analysis of PAK6 expression in HeLa (A), LOVO (B), mouse brain (C), rat brain (D) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-PAK6 antibody, IHC(P) IHC(P): Rat Brain Tissue 100 μg Log in to see 4 to 6 Days
$200.00
Details
Dog Rabbit Un-conjugated IHC (p) Immunohistochemistry-Paraffin: PAK6 Antibody [NLS6942] - Human Lung, Non-Small Cell Carcinoma. formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Immunohistochemistry-Paraffin: PAK6 Antibody [NLS6942] - Analysis of anti-PAK6 antibody with human brain, neurons and glia at 3.5 ug/ml. 0.05 mL Log in to see 10 to 13 Days
$447.56
Details
Human Rabbit Un-conjugated EIA, IF, IHC (p), WB   0.4 mL Log in to see 25 to 30 Days
$375.38
Details
Dog Rabbit Un-conjugated IHC (p) Anti-PAK6 antibody  ABIN1049227 IHC staining of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 7 to 9 Days
$451.00
Details
Human Rabbit Un-conjugated IHC (p) Anti-PAK6 antibody  ABIN1049228 IHC staining of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 7 to 9 Days
$451.00
Details

PAK6 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-P21-Activated Kinase 6 Antibodies

  1. Human Polyclonal PAK6 Primary Antibody for IHC, ELISA - ABIN1002959 : Jaffer, Chernoff: p21-activated kinases: three more join the Pak. in The international journal of biochemistry & cell biology 2002 (PubMed)
    Show all 3 Pubmed References

  2. Dog (Canine) Polyclonal PAK6 Primary Antibody for IHC (p) - ABIN4343483 : Kwek, Dao, Roy, Hou, Alajajian, Simko, Small, Fong: Diversity of antigen-specific responses induced in vivo with CTLA-4 blockade in prostate cancer patients. in Journal of immunology (Baltimore, Md. : 1950) 2012 (PubMed)

  3. Human Polyclonal PAK6 Primary Antibody for ELISA, ICC - ABIN4343485 : Raja, Sahasrabuddhe, Radhakrishnan, Syed, Solanki, Puttamallesh, Balaji, Nanjappa, Datta, Babu, Renuse, Patil, Izumchenko, Prasad, Chang, Rangarajan, Sidransky, Pandey, Gowda, Chatterjee: Chronic exposure to cigarette smoke leads to activation of p21 (RAC1)-activated kinase 6 (PAK6) in non-small cell lung cancer cells. in Oncotarget 2016 (PubMed)

More Antibodies against P21-Activated Kinase 6 Interaction Partners

Human P21-Activated Kinase 6 (PAK6) interaction partners

  1. RhoD recruits Pak6 to the plasma membrane to antagonize RhoC (show RHOC Antibodies) signaling during cell contraction and blebbing

  2. PAK6 localization to cell-cell adhesions is Cdc42 (show CDC42 Antibodies)-dependent

  3. p21-activated kinase 6 (PAK6) as a novel interactor of leucine-rich repeat kinase 2 (LRRK2 (show LRRK2 Antibodies)), a kinase involved in Parkinson's disease

  4. PAK6 is directly targeted by miR (show MLXIP Antibodies)-328. miR (show MLXIP Antibodies)-328 inhibits cell growth and promotes cell apoptosis in prostate cancer cells.

  5. negative correlation between PAK6 and EZH2 (show EZH2 Antibodies) expression was observed in hepatoma tissues from HCC (show FAM126A Antibodies) patients. These data identified the tumor suppressive role and potential underlying mechanism of PAK6 in hepatocarcinogenesis

  6. the results of the present study suggested that miR (show MLXIP Antibodies)-429 inhibits the migration and invasion of colon cancer cells, partly at least, by mediating the expression of PAK6, as well as the activity of cofilin (show CFL1 Antibodies) signaling

  7. we report that in colon cancer PAK6 promotes tumor progression and chemoresistance both in vitro and in vivo

  8. PAK6 is specifically required for carcinoma cell-cell dissociation downstream of hepatocyte growth factor (HGF (show HGF Antibodies)) for both DU145 prostate cancer and HT29 colon cancer cells.

  9. PAK5 plays an essential role in the initiation and progression of hepatocellular carcinoma.

  10. These results demonstrate that androgen-stimulated PAK6 activation is mediated through a direct interaction between AR and PAK6 and PAK6 activation promotes prostate cancer cells motility and invasion.

Mouse (Murine) P21-Activated Kinase 6 (PAK6) interaction partners

  1. p21-activated kinase 6 (PAK6) as a novel interactor of leucine-rich repeat kinase 2 (LRRK2 (show LRRK2 Antibodies)), a kinase involved in Parkinson's disease

  2. data suggest that PAK-6 p21 (show D4S234E Antibodies)-activated kinase plays a role in weight gain unrelated to exercise and caloric intake

  3. functional deficits in PAK5 (show PAK7 Antibodies), PAK6 and PAK5/PAK6 knockout mice

  4. Our results indicate that Pak5 (show PAK7 Antibodies) and Pak6 together are not required for viability, but are required for a normal level of locomotion and activity as well as for learning and memory.

P21-Activated Kinase 6 (PAK6) Antigen Profile

Protein Summary

This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with PAK6

  • p21 protein (Cdc42/Rac)-activated kinase 6b (pak6b) antibody
  • p21 protein (Cdc42/Rac)-activated kinase 6 (PAK6) antibody
  • p21-activated kinase 6 (LOC100348921) antibody
  • p21 protein (Cdc42/Rac)-activated kinase 6 (Pak6) antibody
  • 4732456M09 antibody
  • PAK5 antibody
  • pak6 antibody
  • si:ch211-158b22.3 antibody

Protein level used designations for PAK6

p21 protein (Cdc42/Rac)-activated kinase 6 , p21-activated kinase 6 , serine/threonine-protein kinase PAK 6 , PAK-6 , p21(CDKN1A)-activated kinase 6 , p21 (CDKN1A)-activated kinase 6

GENE ID SPECIES
567874 Danio rerio
100172971 Pongo abelii
100348921 Oryctolagus cuniculus
56924 Homo sapiens
539224 Bos taurus
214230 Mus musculus
296078 Rattus norvegicus
428837 Gallus gallus
487490 Canis lupus familiaris
100153981 Sus scrofa
100071463 Equus caballus
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