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Required to suppress inappropriate homologous recombination, thereby playing a central role DNA repair and in the maintenance of genomic stability (By similarity). Additionally we are shipping PARP1 Binding Protein Antibodies (23) and many more products for this protein.
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PARI inhibits homologous recombination in vivo, and its knockdown suppresses the UV sensitivity of RAD18 (show RAD18 Proteins)-depleted cells
PARI overexpression promotes genomic instability and pancreatic tumorigenesis.
Knockdown of C12orf48 by siRNA in HeLa cells significantly suppressed their growth
PARI suppresses inappropriate recombination events at mammalian replication forks.
Demonstrated that C12orf48 protein could directly interact with Poly(ADP-ribose) Polymerase-1 (PARP-1 (show PARP1 Proteins)). Knockdown of C12orf48 by siRNA in PDAC cells significantly suppressed their growth.
Parpbp(4930547N16Rik) is strongly co-expressed with known cancer-associated genes.
Required to suppress inappropriate homologous recombination, thereby playing a central role DNA repair and in the maintenance of genomic stability (By similarity).
PARP-1 binding protein
, PARP1-binding protein
, PCNA-interacting partner
, antisense RNA overlapping MCH gene protein