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PMS1 encodes a protein belonging to the DNA mismatch repair mutL/hexB family. Additionally we are shipping PMS1 Proteins (3) and many more products for this protein.
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Genome-wide association study identifies variants in PMS1 associated with serum ferritin (show FTL Antibodies) in a Chinese population.
These studies establish that the Mlh1 (show MLH1 Antibodies)-Pms1 endonuclease is required for MMR (show MRC1 Antibodies) in a previously uncharacterized Exo1 (show EXO1 Antibodies)-independent MMR (show MRC1 Antibodies) pathway.
PMS1 is most likely deregulated by post-transcriptional modification in oral squamous cell carcinoma.
The expression of hMLH1 (show MLH1 Antibodies) and hPMS1 was significantly low in some large B-cell lymphomas and in mantle cell lymphomas of the blastoid type and may be related to the natural history of these neoplasms.
Data show that DNA damage induces the accumulation of hPMS1, hPMS2, and hMLH1 (show MLH1 Antibodies) through ataxia-telangiectasia-mutated (ATM (show ATM Antibodies))-mediated protein stabilization.
hPMS1 may be useful as CD4 (show CD4 Antibodies)+ helper T cell antigens for immunotherapy of pancreatic cancer patients.
This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome.
PMS1 protein homolog 1
, postmeiotic segregation 1
, PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
, PMS1 postmeiotic segregation increased 1
, PMS1 protein homolog 1-like
, postmeiotic segregation increased 1
, DNA mismatch repair protein PMS1
, human homolog of yeast mutL
, mismatch repair gene PMSL1
, rhabdomyosarcoma antigen MU-RMS-40.10B
, rhabdomyosarcoma antigen MU-RMS-40.10E