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may act as a transcriptional regulator of gene expression during Schwann cell differentiation and myelination [RGD, Feb 2006].. Additionally we are shipping POU3F1 Antibodies (69) and POU3F1 Kits (3) and many more products for this protein.
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Combined high OATP1A2/high OCT6 may be a potential predictor of response to anthracycline/taxane-based chemotherapy in breast cancer
CpG island hypermethylation contributes to down-regulation of Oct-6 mRNA expression in hepatocellular carcinoma.
Our results suggest that Tst-1 (show CCDC6 Proteins) and Skn-1a (show POU2F3 Proteins) regulate expression of MMPs in keratinocytes and effect both the expression and activation of these proteolytic enzymes.
Strict control of Pou3f1 transgene expression is critical to proper myelination, and factors responsible for Pouf31 downregulation during myelination may play important roles in the development of peripheral neuropathies.
The expression of the zebrafish Oct-6 protein is consistent with the notion that it functions as a 'competence factor' in promyelin cells to execute the myelination program.
Oct6 predominantly forms homodimers on MORE cis (show CISH Proteins) elements in NS5 (show RAF1 Proteins) mouse neural stem cells
Pou3f1 promotes the neural fate commitment of pluripotent stem cells through a dual role, activating internal neural induction programs and antagonizing extrinsic neural inhibitory signals
Oct-6 and Oct-11 contribute to the regulation of loricrin gene transcription via interaction with AP-1 factors and Sp1/Sp3.
Crystal structure of the dimeric Oct6 POU domain bound to palindromic MORE motif DNA
POU3F1, but not POU5F1, is an intrinsic regulator of GDNF-induced survival and self-renewal of mouse spermatogonial stem cells.
A cell type-specific allele of the POU gene Oct-6 reveals Schwann cell autonomous function in nerve development and regeneration
Brn-2 function largely overlaps with that of Oct-6 in driving the transition from promyelinating to myelinating Schwann cells
Data show that Oct-6 normally represses Wnt1 expression in the early diencephalon and replacement by Brn-1 as a weaker inhibitor is no longer sufficient to maintain the necessary level of repression in the mouse mutant.
may act as a transcriptional regulator of gene expression during Schwann cell differentiation and myelination
, POU domain transcription factor SCIP
, POU domain, class 3, transcription factor 1
, octamer-binding protein 6
, octamer-binding transcription factor 6
, octoamer transcription factor-6
, suppressed cAMP-inducible POU
, POU class 3 homeobox 1
, POU domain gene 50
, POU domain protein ZP-50
, octamer binding factor oct6