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anti-Paired Box 6 (PAX6) Antibodies

PAX6 encodes paired box gene 6, one of many human homologs of the Drosophila melanogaster gene prd. Additionally we are shipping PAX6 Proteins (10) and PAX6 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PAX6 25509 P63016
PAX6 5080 P26367
PAX6 18508 P63015
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Top anti-PAX6 Antibodies at antibodies-online.com

Showing 10 out of 240 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-PAX6 Antibody Titration: 0.2-1 ug/mlPositive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated IF, WB PAX6  western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the PAX6 antibody detected the PAX6  protein (arrow). Confocal immunofluorescent analysis of PAX6 Antibody (Ascites) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-mouse lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).DAPI was used to stain the cell nuclear (blue). 0.1 mL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated WB PAX6 Antibody  western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the PAX6 antibody detected the PAX6 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated FACS, IF, IHC (p), WB Western blot analysis of PAX6 Antibody (Center) (ABIN390916) in Hela cell line lysates (35 µg/lane). PAX6 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human brain tissue with PAX6 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of PAX6 Antibody (Center) in Hela cell line lysates (35ug/lane). PAX6 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, IF, WB Confocal immunofluorescent analysis of PAX6 Antibody(Cat#AP53180PU-N) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).DAPI was used to stain the cell nuclear (blue). PAX6 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PAX6 Antibody for immunohistochemistry. Clinical relevance has not been evaluated. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Mouse Goat Un-conjugated ELISA, WB ABIN190794 (0.5µg/ml) staining of Mouse Eye lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated IF, IHC (p), WB Western blot analysis of PAX6-T373 (ABIN652261) in Y79 cell line lysates (35 µg/lane). PAX6 (arrow) was detected using the purified polyclonal antibody. PAX6-T373 Antibody (ABIN652261) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IF, IHC (p), WB PAX6 Antibody (ABIN656844) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details

PAX6 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-PAX6 Antibodies

  1. Human Polyclonal PAX6 Primary Antibody for EIA, IF - ABIN954011 : Gosmain, Marthinet, Cheyssac, Guérardel, Mamin, Katz, Bouzakri, Philippe: Pax6 controls the expression of critical genes involved in pancreatic {alpha} cell differentiation and function. in The Journal of biological chemistry 2010 (PubMed)
    Show all 2 references for ABIN954011

  2. Human Polyclonal PAX6 Primary Antibody for IF, IHC (p) - ABIN656844 : Vuzman, Polonsky, Levy: Facilitated DNA search by multidomain transcription factors: cross talk via a flexible linker. in Biophysical journal 2010 (PubMed)
    Show all 2 references for ABIN656844

  3. Human Polyclonal PAX6 Primary Antibody for IF, IHC (p) - ABIN652261 : Zhang, Yamada, Fan, Bangaru, Lin, Yang: The beta subunit of voltage-gated Ca2+ channels interacts with and regulates the activity of a novel isoform of Pax6. in The Journal of biological chemistry 2010 (PubMed)

  4. Human Polyclonal PAX6 Primary Antibody for WB - ABIN374758 : von Holst, Egbers, Prochiantz, Faissner: Neural stem/progenitor cells express 20 tenascin C isoforms that are differentially regulated by Pax6. in The Journal of biological chemistry 2007 (PubMed)

  5. Human Polyclonal PAX6 Primary Antibody for EIA, WB - ABIN453253 : Firsova, Markitantova, Smirnova, Panova, Sukhikh, Zinovieva: Temporal and spatial distribution of PAX6 gene expression in the developing human eye. in Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections / translated from Russian 2009 (PubMed)

  6. Chicken Polyclonal PAX6 Primary Antibody for WB - ABIN2777559 : Kim, Noh, Ryu, Kim, Lee, Kim, Lee, Kim, Choi: Phosphorylation and transactivation of Pax6 by homeodomain-interacting protein kinase 2. in The Journal of biological chemistry 2006 (PubMed)

More Antibodies against PAX6 Interaction Partners

Xenopus laevis Paired Box 6 (PAX6) interaction partners

  1. signaling via Pax6 expression through Shp2-binding sites of XFrs3 is necessary for the eye development in Xenopus laevis

  2. Our results show that the expression of Pax6 and Pax7 (show PAX7 Antibodies) is widely maintained in the adult brain of Xenopus

Human Paired Box 6 (PAX6) interaction partners

  1. findings suggest that PAX6+/- is associated with smaller pineal size, lower melatonin secretion and greater parental report of sleep disturbances in children; further studies are needed to explore the potential use of melatonin replacement for improving sleep quality in patients with PAX6+/-

  2. In post-mortem substantia nigra from Parkinson's disease patients, a reduced number of PAX6 expressing cells were found.

  3. We analyzed the PAX6 gene in a Bosma arrhinia microphthalmia syndrome patient but found no variation or mutation that could constitute or establish a causal association in our patient

  4. Variants in TRIM44 (show TRIM44 Antibodies) Cause Aniridia by Impairing PAX6 Expression

  5. MicroRNA-7 inhibits the malignant phenotypes of nonsmall cell lung cancer in vitro by targeting Pax6

  6. ChIP experiments confirmed that Pdx1 (show PDX1 Antibodies) activates the expression of the downstream transcription factors, Ngn3 (show NEUROG3 Antibodies) and Pax6, by combined with the promoter regions of insulin (Insulin (show INS Antibodies)-P), Ngn3 (Ngn3 (show NEUROG3 Antibodies)-P), and Pax6 (Pax6-P).

  7. we reported the results of the clinical and molecular evaluation of a threegeneration Chinese family with aniridia and identified a rare heterozygous M1K mutation in PAX6.

  8. Trans-placental BPA (show DST Antibodies) exposure down-regulated gene expression of Sox2 (show SOX2 Antibodies) and Pax6 potentially underlying the adverse effect on childhood neuronal development. [Meta-analysis]

  9. Molecular analysis identified two compound heterozygous TYR (show TYR Antibodies) mutations known to cause OCAIA (show TYR Antibodies) and cosegregate with oculocutaneous albinism. In addition, we identified a novel heterozygous PAX6 mutation confirming the atypical aniridia phenotype.

  10. SOX4, SOX11 (show SOX11 Antibodies), and PAX6 were significant for tumor type.

Cow (Bovine) Paired Box 6 (PAX6) interaction partners

  1. Some polymorphisms in PAX6 are associated with growth traits at some ages, and may be used as candidates for marker-assisted selection in beef cattle breeding program.

Mouse (Murine) Paired Box 6 (PAX6) interaction partners

  1. c.718C>T transitional mutation of PAX6 has been found to underlie the aniridia, which showed an autosomal dominant inheritance pattern in this northeastern Chinese family

  2. novel mutation in the PAX6 gene has been identified in a Chinese family affected with aniridia

  3. the Pax6 paired domain has roles in neural tube patterning and peripheral nervous system development

  4. This study demonstrated that Pax6 is expressed in astrocytes and binds to the GLT-1 promoter in vitro and in vivo.

  5. Pax6 inactivation in the adult pancreas reveals ghrelin (show GHRL Antibodies) as endocrine cell maturation marker.

  6. results indicate that Pax6 is required by thalamic progenitors for the normal molecular patterning of the thalamic neurons that they generate

  7. Pax6 expression is essential for horizontal basal cells to differentiate into neuronal cells during regeneration.

  8. Upper-layer neuron production was increased in double-transgenic mouse embryos with sustained Pax6 expression in the neurogenic lineage. Increased basal progenitors existed in the subventricular zone and the intermediate zone of the neocortex.

  9. NFIA (show NFIA Antibodies) and NFIB (show NFIB Antibodies) are endogenously expressed in gradients with high caudo-medial to low rostro-lateral expression ... this expression pattern deviates from that of PAX6, suggesting that PAX6 does not drive Nfi (show NFIC Antibodies) expression

  10. The expression dynamics shows that Pax6 localizes at XY body during meiotic prophase I, especially in the mid-phase of pachytene spermatocytes which suggests that Pax6 may have some function in inactivation of sex chromosomes during meiosis.

Zebrafish Paired Box 6 (PAX6) interaction partners

  1. Pax6 has an evolutionarily conserved function in establishing the temporospatial expression of Shh (show SHH Antibodies) in the mid-diencephalic organizer in vertebrates.

  2. loss of Pax6b or Hb9 (show MNX1 Antibodies) independently results in the loss of insulin (show INS Antibodies) expression, the data reveal a novel cross-talk between the two essential regulators of early beta-cell differentiation.

  3. The results suggest that decreased Pax6 expression is permissive for axon regeneration and extensive searching, while higher levels of Pax6 are associated with restoration of topography.

  4. This study supports the hypothesis that the Pax6 transcription factor is also a signaling molecule with direct non-cell autonomous activity.

  5. following a postulated whole-genome duplication event in an ancestral teleost, duplicates pax6a and pax6b encode transcription factors required for eye, brain, olfactory system, and pancreas development

  6. Pax6 interacts with itself via both the paired domain and the homeodomain. Pax6 interaction with itself superactivates Pax6 mediated transactivation.

PAX6 Antigen Profile

Protein Summary

This gene encodes paired box gene 6, one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as aniridia and Peter's anomaly. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with anti-Paired Box 6 (PAX6) Antibodies

  • paired box 6 (PAX6) antibody
  • paired box 6 (pax6) antibody
  • paired box 6 (Pax6) antibody
  • paired box 6 (pax6-a) antibody
  • paired box 6 (pax6-b) antibody
  • paired box gene 6 (Pax6) antibody
  • paired box gene 6a (pax6a) antibody
  • 1500038E17Rik antibody
  • AEY11 antibody
  • AN antibody
  • AN2 antibody
  • cb280 antibody
  • D11S812E antibody
  • Dey antibody
  • fc20e07 antibody
  • Gsfaey11 antibody
  • MGC52531 antibody
  • MGDA antibody
  • Pax-6 antibody
  • pax-a antibody
  • pax6 antibody
  • Pax6.1 antibody
  • pax6a antibody
  • pax6b antibody
  • PAXZF-A antibody
  • paxzfa antibody
  • pax[zf-a] antibody
  • Sey antibody
  • WAGR antibody
  • wu:fc20e07 antibody
  • XLPAX6 antibody
  • xpax6 antibody
  • zfpax-6a antibody
  • zfpax-6b antibody

Protein level used designations for anti-Paired Box 6 (PAX6) Antibodies

paired box protein Pax-6 , paired box 6 , paired box gene 6 , oculorhombin , paired box homeotic gene 6 , paired box gene 6 a , aniridia type II protein , paired box homeotic gene-6 , paired box gene 6 (aniridia, keratitis) , paired box protein PAX6 , paired box gene 6 b , paired domain transcription factor variant B , paired-type homeodomain Pax-6 protein , Dickie's small eye , small eye , etID309716.25 , paired box protein Pax[Zf-a] , pax-6

GENE ID SPECIES
100146390 Equus caballus
695746 Macaca mulatta
100303503 Saccoglossus kowalevskii
100552301 Anolis carolinensis
100590220 Nomascus leucogenys
554264 Ovis aries
25509 Rattus norvegicus
379100 Xenopus laevis
395943 Gallus gallus
5080 Homo sapiens
483441 Canis lupus familiaris
286857 Bos taurus
100009018 Oryctolagus cuniculus
100337586 Xenopus laevis
18508 Mus musculus
30567 Danio rerio
Selected quality suppliers for anti-PAX6 (PAX6) Antibodies
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