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PAX6 antibody (N-Term)

PAX6 Reactivity: Human, Mouse, Rat, Chicken WB, IF, FACS Host: Mouse Monoclonal PAX6-498 unconjugated
Catalog No. ABIN6940257
  • Target See all PAX6 Antibodies
    PAX6 (Paired Box 6 (PAX6))
    Binding Specificity
    • 26
    • 22
    • 16
    • 15
    • 10
    • 8
    • 6
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-300, N-Term
    Reactivity
    • 114
    • 71
    • 67
    • 14
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Chicken
    Host
    • 96
    • 38
    • 1
    Mouse
    Clonality
    • 86
    • 48
    Monoclonal
    Conjugate
    • 70
    • 8
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This PAX6 antibody is un-conjugated
    Application
    • 97
    • 49
    • 46
    • 40
    • 30
    • 26
    • 15
    • 14
    • 13
    • 9
    • 8
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
    Specificity
    Pax genes contain paired domains with strong homology to genes in Drosophila, which are involved in programming early development. Lesions in the Pax-6 gene account for most cases of aniridia, a congenital malformation of the eye, chiefly characterized by iris hypoplasia, which can cause blindness. Pax-6 is involved in other anterior segment malformations besides aniridia, such as Peters' anomaly, a major error in the embryonic development of the eye with corneal clouding with variable iridolenticulocorneal adhesions. The Pax-6 gene encodes a transcriptional regulator that recognizes target genes through its paired-type DNA-binding domain. The paired domain is composed of two distinct DNA-binding subdomains, the amino-terminal subdomain and the carboxy-terminal subdomain, which bind respective consensus DNA sequences. The human Pax-6 gene produces two alternatively spliced isoforms that have the distinct structure of the paired domain.
    Purification
    Purified by Protein A/G
    Immunogen
    Recombinant fragment (N-terminus, aa 1-300) of human PAX6 protein
    Clone
    PAX6-498
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product PAX6 Primary Antibody
  • Application Notes

    Positive Control: Pancreas or Cerebellum.

    Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Western Blot (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-80 °C
    Storage Comment
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Expiry Date
    24 months
  • Target
    PAX6 (Paired Box 6 (PAX6))
    Alternative Name
    PAX6 (PAX6 Products)
    Synonyms
    pax6 antibody, an2 antibody, mgda antibody, wagr antibody, pax-6 antibody, pax6a antibody, xpax6 antibody, XLPAX6 antibody, MGC52531 antibody, PAX-6 antibody, AN antibody, AN2 antibody, D11S812E antibody, MGDA antibody, WAGR antibody, Pax-6 antibody, pax6b antibody, 1500038E17Rik antibody, AEY11 antibody, Dey antibody, Gsfaey11 antibody, Sey antibody, PAXZF-A antibody, Pax6.1 antibody, cb280 antibody, fc20e07 antibody, pax-a antibody, pax[zf-a] antibody, paxzfa antibody, wu:fc20e07 antibody, zfpax-6a antibody, zfpax-6b antibody, paired box 6 antibody, paired box 6 L homeolog antibody, paired box 6 S homeolog antibody, paired box 6a antibody, PAX6 antibody, pax6 antibody, Pax6 antibody, pax6.L antibody, pax6.S antibody, pax6a antibody
    Molecular Weight
    47kDa
    Gene ID
    5080
    UniProt
    P26367
    Pathways
    Peptide Hormone Metabolism, Carbohydrate Homeostasis
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