You are viewing an incomplete version of our website. Please click to reload the website as full version.

Paired-Like Homeodomain 1 Proteins (PITX1)

PITX1 encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. Additionally we are shipping PITX1 Antibodies (50) and PITX1 Kits (6) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PITX1 5307 P78337
PITX1 113983 Q99NA7
PITX1 18740 P70314
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top PITX1 Proteins at antibodies-online.com

Showing 6 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$2,812.33
Details
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$2,830.67
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,843.50
Details

PITX1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Rat (Rattus)

Mouse (Murine)

More Proteins for Paired-Like Homeodomain 1 (PITX1) Interaction Partners

Human Paired-Like Homeodomain 1 (PITX1) interaction partners

  1. PTP1B (show PTPN1 Proteins) dephosphorylates PITX1 to weaken its protein stability and the transcriptional activity for p120RasGAP (show RASA1 Proteins) gene expression

  2. To date, at least ten loci and four non-syndromic polydactyly-causing genes, including the GLI3 (show GLI3 Proteins) gene, the ZNF141 gene, the MIPOL1 (show MIPOL1 Proteins) gene and the PITX1 gene, have been identified. (Review)

  3. Low PITX1 expression is associated with lung metastasis in osteosarcoma.

  4. We discuss the genetic abnormality that causes Liebenberg syndrome, the genomic rearrangement at the PITX1 locus on chromosome 5.

  5. Down-regulation of PITX1 expression might contribute to the progression of cutaneous malignant melanoma via promoting cell proliferative activity

  6. PITX1 regulates HIF-1a (show HIF1A Proteins) activity by binding to HIF-1b and regulatingHIF recruitment to specific target promoters.

  7. DUX4 gene is activated in a small number of myonuclei, the DUX4 proteins diffuse to adjacent nuclei where they activate target genes such as PITX1.

  8. Lienberg syndrome results from a misexpression of PITX1 in upper extremities.

  9. A deletion in H2AFY (show H2AFY Proteins) gene and 190,428bp of its downstream region contains a regulatory sequence that suppresses the expression of PITX1 in the upper limb buds and causes Liebenberg syndrome.

  10. Identified two deletions and a translocation 5' of PITX1.

Mouse (Murine) Paired-Like Homeodomain 1 (PITX1) interaction partners

  1. Pitx1 influences hindlimb morphology both through the activation of hindlimb-specific enhancers as well as through the hindlimb-specific modulation of enhancers that are active in both sets of limbs

  2. The results suggest that PITX2 (show PITX2 Proteins) and PITX1 have overlapping roles in thyrotroph function and response to hypothyroidism.

  3. PITX1 haploinsufficiency may cause a developmental field defect preferentially affecting the lateral lower leg.

  4. It was shown that, firstly, Pitx1 influences hindlimb outgrowth by regulating Tbx4 (show TBX4 Proteins) expression levels and that, subsequently,Pitx1 shapes hindlimb bone and soft tissue morphology independently of Tbx4 (show TBX4 Proteins).

  5. These findings provide evidence that c-Abl (show ABL1 Proteins) participates in modulating Pitx1 expression in the apoptotic response to DNA damage.

  6. Thus, Pitx1 and Pitx2 (show PITX2 Proteins) genes are required for sustained hindlimb bud growth and formation of hindlimbs

  7. PITX1 autoregulation depends on DNA-binding and trans-activation domains of Pitx1 and it may be responsible for establishment and/or maintenance of the Pitx1 expression domain.

  8. Results suggest that pituitary homeobox 1 (Pitx-1) can direct transactivation of the mouse gonadotropin-releasing hormone receptor (show GNRHR Proteins) gene, in part by DNA binding and in part by an action of Pitx-1 as a cofactor for AP-1 (show JUN Proteins)

  9. Although PITX1 protein is present in expression pattern similar to PITX2 (show PITX2 Proteins) throughout pituitary development, it has less prominent role than PITX2 (show PITX2 Proteins).

  10. These results demonstrate that Pitx1, but not Tbx4 (show TBX4 Proteins), determines the morphological identity of hindlimb tissues.

Xenopus laevis Paired-Like Homeodomain 1 (PITX1) interaction partners

  1. Pitx1 is expressed in hindlimbs and expression is similar in both developing and regenerating limb buds.

PITX1 Protein Profile

Protein Summary

This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. Members of this family are involved in organ development and left-right asymmetry. This protein acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin.

Gene names and symbols associated with PITX1

  • paired-like homeodomain 1 (PITX1)
  • paired-like homeodomain 1 (pitx1)
  • paired-like homeodomain 1 (Pitx1)
  • paired-like homeodomain transcription factor 1 (pitx1)
  • paired-like homeodomain transcription factor 1 (Pitx1)
  • Pitx1 protein (pitx1)
  • Bft protein
  • CCF protein
  • LBNBG protein
  • MGC79589 protein
  • P-OTX protein
  • PITX1 protein
  • Potx protein
  • Ptx1 protein
  • X-PITX-1 protein
  • xPitx1 protein
  • zgc:136976 protein

Protein level used designations for PITX1

paired-like homeodomain 1 , paired-like homeodomain transcription factor 1 , pituitary homeobox 1 , Pitx2 , hindlimb expressed homeobox protein backfoot , hindlimb-expressed homeobox protein backfoot , homeobox protein PITX1 , pituitary homeo box 1 , pituitary otx-related factor , cPTX1 , homeobox protein P-OTX , pituitary OTX-related factor , xPitx1

GENE ID SPECIES
462072 Pan troglodytes
493226 Xenopus (Silurana) tropicalis
508754 Bos taurus
100009361 Oryctolagus cuniculus
5307 Homo sapiens
374201 Gallus gallus
481513 Canis lupus familiaris
113983 Rattus norvegicus
678598 Danio rerio
18740 Mus musculus
398122 Xenopus laevis
Selected quality suppliers for PITX1 Proteins (PITX1)
Did you look for something else?